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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Seizure Control as a New Metric in Assessing Efficacy of Tumor Treatment in Patients With Low Grade GliomaNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, epilepsy, low grade glioma, neoplasm, nervous system disorderActive, not recruitingNot stated2026-10-07NCT04553757
A Study to Assess a Medicine Called Tovorafenib in Japanese Children and Young Adults With Brain Tumourslow grade gliomaActive, not recruitingPhase 12026-10-01NCT07441707
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGGNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingEarly phase 12026-09-22NCT05555550
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade GliomaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, low grade glioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder, primitive neuroectodermal tumorActive, not recruitingPhase 1 / Phase 22026-09-21NCT01089101
SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade GliomaNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, central neurocytoma, epithelial neoplasm, ganglioglioma, glioma, low grade glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumorRecruitingPhase 1 / Phase 22026-09-11NCT04923126
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Gliomalow grade gliomaRecruitingPhase 32026-09-11NCT04166409
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomaslow grade gliomaRecruitingPhase 22026-09-03NCT07110246
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid TumorsHead and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Thoracic Neoplasms, brain disorder, bronchial neoplasm, bronchogenic carcinoma, cancer, central nervous system cancer, central nervous system disorder, differentiated thyroid carcinoma, endocrine system disorder, epithelial neoplasm, glioma, low grade glioma, lung disorder, lung neoplasm, malignant endocrine neoplasm, malignant glioma, melanocytic neoplasm, melanoma, neoplasm, nervous system disorder, neuroendocrine neoplasm, neuroepithelial neoplasm, non-small cell lung carcinoma, primitive neuroectodermal tumor, respiratory system disorder, respiratory tract neoplasm, skin disorder, skin neoplasm, thyroid gland disorder, thyroid tumorActive, not recruitingPhase 12026-09-01NCT05538130
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, low grade glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-08-18NCT04485559
A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade GliomaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, low grade glioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, optic pathway glioma, peripheral nervous system disorderActive, not recruitingPhase 32026-08-13NCT03871257
Mind-Body Intervention in Glioma CouplesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioblastoma, glioma, grade III glioma, low grade glioma, malignant glioma, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingNot applicable2026-08-12NCT03244995
A Phase I Study of Mebendazole for the Treatment of Pediatric GliomasNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), brain disorder, brain stem glioma, brainstem cancer, central nervous system cancer, central nervous system disorder, cranial nerve neoplasm, cranial nerve neuropathy, diffuse intrinsic pontine glioma, epithelial neoplasm, eye disorder, glioblastoma, glioma, gliosarcoma, low grade glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, optic nerve disorder, optic nerve glioma, optic nerve neoplasm, peripheral nervous system neoplasm, pilocytic astrocytoma, pilomyxoid astrocytoma, primitive neuroectodermal tumorActive, not recruitingPhase 1 / Phase 22026-08-06NCT01837862
Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, low grade glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorNot yet recruitingPhase 22026-07-30NCT07735819
Niraparib In Recurrent IDH 1/2 GliomasNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingEarly phase 12026-07-24NCT05406700
Neurocognitive Assessment CNSL and LGGCognition Disorders, Cognitive Dysfunction, Neoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, cognitive disorder, low grade glioma, neoplasm, nervous system disorder, primary central nervous system lymphoma, psychiatric disorderNot yet recruitingNot applicable2026-07-17NCT07710131
Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade GliomasCognition Disorders, Cognitive Dysfunction, cognitive disorder, low grade glioma, psychiatric disorderRecruitingNot applicable2026-07-14NCT03948490
MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric GliomasNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 1 / Phase 22026-07-10NCT06712875
A Study of Avutometinib for People With Solid Tumor CancersNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, low grade glioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, neurofibroma, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder, peripheral nervous system neoplasm, plexiform neurofibroma, primitive neuroectodermal tumor, refractory malignant neoplasmActive, not recruitingPhase 12026-06-15NCT06104488
Low-grade Gliomas in Argentina: Incidence, Survival, and Therapeutic StrategiesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioma, low grade glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-06-08NCT07631338
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)Noonan syndrome 5, low grade gliomaActive, not recruitingPhase 32026-05-14NCT05566795
Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, low grade glioma, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder, peripheral nervous system neoplasm, plexiform neurofibroma, primitive neuroectodermal tumorActive, not recruitingPhase 22026-04-24NCT03363217
Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Gliomachildhood malignant neoplasm, low grade glioma, neoplasmRecruitingNot applicable2026-04-01NCT07506239
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV GliomasNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingPhase 12026-03-13NCT03749187
Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS TrialNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, brain cancer, brain disorder, central nervous system cancer, central nervous system disorder, low grade glioma, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerRecruitingPhase 22026-02-10NCT06132685
A Living Tissue Bank of Patient-Derived Organoids From Glioma TumorsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-01-27NCT04865315