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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Targeted Pediatric High-Grade Glioma TherapyNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, diffuse midline glioma, H3 K27M-mutant, epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-09-08NCT05839379
Study of Olutasidenib and Temozolomide in HGGNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, diffuse midline glioma, H3 K27M-mutant, epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumor, spinal cord disorder, spinal cord neoplasmRecruitingPhase 22026-09-01NCT06161974
Mind-Body Intervention in Glioma CouplesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioblastoma, glioma, grade III glioma, low grade glioma, malignant glioma, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingNot applicable2026-08-12NCT03244995
Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain TumorsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot applicable2026-07-20NCT04479696
Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic oligoastrocytoma, anaplastic oligodendroglioma, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, oligoastrocytoma, oligodendroglioma, primitive neuroectodermal tumorRecruitingPhase 22026-07-16NCT04623931
Safety and Effectiveness Evaluation of Temozolomide (Amitzo, NanoAlvand) in Patients With Grade III and IV Glioma TumorsNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioma, grade III glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-06-30NCT07675070
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK FusionNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingEarly phase 12026-06-29NCT06333899
Combination Therapy for the Treatment of Diffuse Midline GliomasNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, diffuse midline glioma, H3 K27M-mutant, epithelial neoplasm, glioma, grade III glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 22026-06-26NCT05009992
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young AdultsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingPhase 12026-06-15NCT04323046
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutantNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, diffuse midline glioma, H3 K27M-mutant, epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 22026-05-29NCT05843253
Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, grade II glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-04-29NCT04540107
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV GliomasNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, low grade glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingPhase 12026-03-13NCT03749187
Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade III glioma, malignant glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingPhase 12026-02-04NCT03389230
Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingNot applicable2026-01-27NCT03251027
Implantable Microdevice In Primary Brain TumorsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic oligodendroglioma, astrocytoma (excluding glioblastoma), brain oligodendroglioma, epithelial neoplasm, glioblastoma, glioma, grade II glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumorRecruitingEarly phase 12025-07-23NCT04135807
Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) ProgressionNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic astrocytoma, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, grade III glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot applicable2025-05-16NCT06975332