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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
VISTA: Valproic Acid, Irinotecan, and Simvastatin for Recurrent GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 22026-09-21NCT07831369
A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational BurdenNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingPhase 22026-08-31NCT04145115
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 2, astrocytoma, IDH-mutant, grade 3, astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, follicular lymphoma, glioblastoma, glioma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumorRecruitingPhase 32026-08-28NCT05303519
Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade GliomasHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, anaplastic oligodendroglioma, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 3, astrocytoma, IDH-mutant, grade 4, diffuse astrocytoma, epithelial neoplasm, follicular lymphoma, glioblastoma, glioma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, malignant glioma, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumorRecruitingPhase 1 / Phase 22026-06-24NCT07468136
Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade GliomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorEnrolling by invitationPhase 12025-06-26NCT06896110
Extensive Resection of Malignant Brain Tumors Using Advanced Imaging TechniquesNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot applicable2024-10-02NCT06623565