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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE TrialNeoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderRecruitingPhase 22026-10-01NCT05222620
Genetic Testing in Guiding Treatment for Patients With Brain MetastasesNeoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 22026-09-28NCT03994796
Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain MetastasesNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 12026-09-25NCT02015117
Single Fraction Stereotactic Radiosurgery or Three to Five Fraction Stereotactic Radiosurgery in Treating Patients With Brain Metastasis That Has Been Removed by SurgeryNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 32026-09-17NCT04114981
Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain MetastasesNeoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 32026-09-16NCT01592968
A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain MetastasesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, acral lentiginous melanoma, brain disorder, central nervous system cancer, central nervous system disorder, melanocytic neoplasm, melanoma, metastatic malignant neoplasm in the brain, metastatic melanoma, neoplasm, nervous system disorder, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasmRecruitingPhase 22026-09-15NCT04511013
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the BrainFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, brain disorder, breast disorder, breast neoplasm, bronchial neoplasm, bronchogenic carcinoma, carcinoma, central nervous system cancer, central nervous system disorder, epithelial neoplasm, kidney cancer, kidney disorder, lung disorder, lung neoplasm, melanocytic neoplasm, melanoma, metastatic malignant neoplasm in the brain, metastatic melanoma, neoplasm, nervous system disorder, neuroendocrine neoplasm, non-small cell lung carcinoma, primitive neuroectodermal tumor, renal cell carcinoma, respiratory system disorder, respiratory tract neoplasm, skin disorder, skin neoplasm, urinary system disorderActive, not recruitingPhase 32026-09-14NCT06500455
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-OncologyLeptomeningeal Neoplasms, Neoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, tumor of meningesRecruitingNot stated2026-09-14NCT04988009
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking AbilityNeoplasms by Site, Thoracic Neoplasms, brain disorder, bronchial neoplasm, bronchogenic carcinoma, central nervous system cancer, central nervous system disorder, lung disorder, lung neoplasm, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, respiratory system disorder, respiratory tract neoplasm, small cell lung carcinomaActive, not recruitingPhase 32026-09-14NCT04804644
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain MetastasisNeoplasms by Site, Thoracic Neoplasms, brain disorder, bronchial neoplasm, bronchogenic carcinoma, central nervous system cancer, central nervous system disorder, lung disorder, lung neoplasm, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, respiratory system disorder, respiratory tract neoplasm, small cell lung carcinomaActive, not recruitingPhase 22026-09-14NCT04516070
Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous SystemNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, cranial nerve neuropathy, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderRecruitingPhase 22026-09-14NCT03270059
Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain MetastasesNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 32026-09-10NCT05438212
Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain MetastasesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, brain disorder, central nervous system cancer, central nervous system disorder, melanocytic neoplasm, melanoma, metastatic malignant neoplasm in the brain, metastatic melanoma, neoplasm, nervous system disorder, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasmActive, not recruitingPhase 22026-08-20NCT01644591
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain TumorsNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderRecruitingPhase 32026-08-19NCT03750227
Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System LesionsNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioblastoma, glioma, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot applicable2026-08-18NCT04047264
Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain MetastasesNeoplasms by Site, Thoracic Neoplasms, brain disorder, bronchial neoplasm, bronchogenic carcinoma, central nervous system cancer, central nervous system disorder, lung disorder, lung neoplasm, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmActive, not recruitingPhase 22026-08-13NCT02971501
A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving PembrolizumabNeoplasms by Site, Thoracic Neoplasms, brain disorder, bronchial neoplasm, bronchogenic carcinoma, central nervous system cancer, central nervous system disorder, lung disorder, lung neoplasm, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 12026-08-12NCT07619599
HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal MetastasesNeoplasms by Site, Skin and Connective Tissue Diseases, brain disorder, breast cancer, breast disorder, breast neoplasm, cancer, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, neoplastic meningitis, nervous system disorder, skin disorder, tumor of meningesActive, not recruitingPhase 12026-08-12NCT03696030
Mind-Body Intervention in Glioma CouplesNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, epithelial neoplasm, glioblastoma, glioma, grade III glioma, low grade glioma, malignant glioma, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingNot applicable2026-08-12NCT03244995
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain MetastasesNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 32026-08-11NCT00950001
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain MetastasesNeoplasms by Site, brain disorder, cancer, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingPhase 32026-08-10NCT03741673
Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction CancersDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, brain disorder, carcinoma, central nervous system cancer, central nervous system disorder, digestive system disorder, digestive system neoplasm, epithelial neoplasm, esophageal adenocarcinoma, esophageal disorder, esophageal squamous cell carcinoma, gastric cardia adenocarcinoma, metastatic malignant neoplasm in the brain, neoplasm, neoplastic meningitis, nervous system disorder, squamous cell carcinoma, squamous cell neoplasm, tumor of meningesActive, not recruitingPhase 12026-07-31NCT04460937
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, brain disorder, breast disorder, breast neoplasm, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, skin disorder, triple-negative breast carcinomaRecruitingPhase 22026-07-21NCT04348747
nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor CortexNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorderActive, not recruitingNot applicable2026-07-16NCT04062305
An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain MetastasisNeoplasms by Site, Skin and Connective Tissue Diseases, brain disorder, breast disorder, breast neoplasm, central nervous system cancer, central nervous system disorder, metastatic malignant neoplasm in the brain, neoplasm, nervous system disorder, skin disorderRecruitingPhase 42026-07-01NCT05376878