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National Institute of Neurological Disorders and Stroke (NINDS)

National Institute of Neurological Disorders and Stroke (NINDS)

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Dynamic Magnetic Resonance Imaging of Human Subarachnoid Space Using Intrathecal Gadolinium ContrastHealthy VolunteersNot yet recruitingPhase 12026-10-09NCT07796360
Neuromodulation to Overcome Severe Restless Legs SyndromeDyssomnias, Parasomnias, Sleep Disorders, Intrinsic, nervous system disorder, psychiatric disorder, restless legs syndrome, sleep-wake disorderNot yet recruitingNot applicable2026-10-09NCT07780032
Longitudinal Natural History Protocol for PRKN- and PINK1-Linked PDPARKINSON DISNot yet recruitingNot stated2026-10-09NCT07613112
Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I)COVID-19, Chronic Disease, Coronaviridae Infections, Disease Attributes, Infections, Nidovirales infectious disease, Orthocoronavirinae infectious disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, RNA Virus Infections, long COVID-19, lung disorder, pneumonia, respiratory system disorder, respiratory tract infectious disorder, viral infectious disease, viral pneumoniaNot yet recruitingPhase 12026-10-09NCT07388550
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological TechniquesDyskinesias, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Tics, nervous system disorderRecruitingNot stated2026-10-09NCT07137442
Telerehabilitation In The Home After Strokebrain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, nervous system disorder, stroke disorder, vascular disorderRecruitingNot applicable2026-10-09NCT06682429
EDAS Revascularization for Symptomatic Intracranial Atherosclerotic Steno-occlusive Disease, Phase IIbArterial Occlusive Diseases, Intracranial Atherosclerosis, arteriosclerosis disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, intracranial arterial disease, intracranial arteriosclerosis, ischemic stroke, nervous system disorder, stroke disorder, vascular disorderNot yet recruitingNot applicable2026-10-08NCT07864649
Low-Dose Naltrexone For ME/CFS: Dose-FindingChronic Disease, Disease Attributes, Neuroinflammatory Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, encephalomyelitis, muscle tissue disorder, musculoskeletal system disorder, myalgic encephalomeyelitis/chronic fatigue syndrome, nervous system disorder, neuromuscular diseaseNot yet recruitingPhase 22026-10-08NCT07285473
Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI StudyParkinson disease, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot stated2026-10-08NCT06960096
Rehabilitation of Airway Protection in Parkinson's DiseaseDeglutition Disorders, Digestive System Diseases, Parkinson disease, Pharyngeal Diseases, basal ganglia disorder, brain disorder, central nervous system disorder, digestive system disorder, esophageal disorder, movement disorder, nervous system disorder, neurodegenerative disease, otorhinolaryngologic disease, parkinsonian disorder, synucleinopathyRecruitingPhase 22026-10-08NCT05700825
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular AtherostenosisArterial Occlusive Diseases, arteriosclerosis disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, intracranial arterial disease, intracranial arteriosclerosis, nervous system disorder, stroke disorder, vascular disorderActive, not recruitingPhase 32026-10-08NCT05047172
Study of Direct Brain Recording and Stimulation for Memory EnhancementNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, nervous system disorder, visual epilepsyEnrolling by invitationNot stated2026-10-08NCT04095026
Deep Brain Stimulation Therapy in Movement DisordersCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Parkinson disease, Tourette syndrome, basal ganglia disorder, brain disorder, central nervous system disorder, essential tremor, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, neurodevelopmental disorder, parkinsonian disorder, psychiatric disorder, synucleinopathy, tic disorderRecruitingNot applicable2026-10-08NCT02119611
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Databasebrain disorder, central nervous system disorder, epilepsy, nervous system disorderRecruitingNot stated2026-10-08NCT02107989
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteersmotor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular diseaseRecruitingNot applicable2026-10-08NCT01900132
Thinking and Memory Problems in People With HIVBlood-Borne Infections, Genital Diseases, HIV Seropositivity, HIV infectious disease, Infections, RNA Virus Infections, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted diseaseRecruitingNot stated2026-10-08NCT01875588
Deep Brain Stimulation Surgery for Movement DisordersDyskinesias, Neurologic Manifestations, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, dystonic disorder, essential tremor, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyRecruitingNot applicable2026-10-08NCT01581580
Evaluation and Treatment of Neurosurgical DisordersNeoplasms by Site, Parkinson disease, Pituitary Neoplasms, basal ganglia disorder, brain disorder, central nervous system cancer, central nervous system disorder, endocrine system disorder, epilepsy, hypothalamic disorder, hypothalamic neoplasm, malignant endocrine neoplasm, movement disorder, neoplasm, nervous system disorder, neurodegenerative disease, parkinsonian disorder, pituitary gland disorder, spinal cord disorder, spinal cord neoplasm, supratentorial cancer, synucleinopathyRecruitingNot stated2026-10-08NCT00060541
Study of New Magnetic Resonance Imaging Methods of the BrainAdult; Brain Mapping; Healthy; Healthy Volunteer; Magnetic Resonance Imaging; fMRIRecruitingNot stated2026-10-08NCT00004577
Botulinum Toxin for the Treatment of Involuntary Movement Disorderscentral nervous system disorder, movement disorder, nervous system disorderRecruitingNot stated2026-10-08NCT00001208
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, frontotemporal dementia with motor neuron disease, metabolic disease, motor neuron disorder, movement disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, tauopathyRecruitingNot stated2026-10-07NCT04363684
Investigating Epilepsy: Screening and EvaluationEpileptic Syndromes, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, focal epilepsy, nervous system disorder, temporal lobe epilepsy, visual epilepsyRecruitingNot stated2026-10-07NCT03478852
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant EpilepsyNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, nervous system disorder, visual epilepsyRecruitingPhase 12026-10-07NCT02531880
Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral NeuropathyInflammation, Neuroinflammatory Diseases, Neurologic Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorder, neuralgia, neuromuscular disease, peripheral nervous system disorderRecruitingNot applicable2026-10-06NCT07822932
Pharmacological Modulation of Brain Oscillations in Memory ProcessingCognition Disorders, Cognitive Dysfunction, Memory Disorders, Memory Loss, Mild Cognitive Impairment, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, epilepsy, nervous system disorder, psychiatric disorder, visual epilepsyRecruitingEarly phase 12026-10-05NCT05594017