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Replimune, Inc.

Replimune, Inc.

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Neoadjuvant RP2 + Nivolumab in Patients With MelanomaNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, retinitis pigmentosa 2, skin disorder, skin neoplasmNot yet recruitingPhase 22026-10-07NCT07862530
Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for AngiosarcomaNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, angiosarcoma, neoplasm, sarcoma, vascular cancerRecruitingPhase 22026-09-01NCT06898970
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]Advanced MelanomaRecruitingPhase 32026-07-15NCT06264180
Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinomaesophageal adenocarcinoma, gastric adenocarcinoma, gastroesophageal junction adenocarcinomaNot yet recruitingPhase 22026-06-05NCT07059611
Phase II Study of RP2 as Immunoprevention in High-Risk Oral Precancerous DiseaseHigh-Risk Oral Precancerous DiseaseRecruitingPhase 22026-04-23NCT06623110
Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin MalignanciesDNA Virus Infections, Infections, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Tumor Virus Infections, adenocarcinoma, basal cell carcinoma, basal cell neoplasm, cancer, carcinoma, cutaneous neuroendocrine carcinoma, epithelial neoplasm, neoplasm, neuroendocrine carcinoma, neuroendocrine neoplasm, polyomavirus infectious disease, primitive neuroectodermal tumor, skin disorder, skin neoplasm, viral infectious diseaseActive, not recruitingPhase 1 / Phase 22026-04-22NCT04349436
RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node MetastasisNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasmRecruitingEarly phase 12026-04-13NCT06216938
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal MelanomaNeoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, Uveal Neoplasms, eye disorder, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, ocular cancer, primitive neuroectodermal tumor, skin disorder, skin neoplasm, uveal disorder, uveal melanomaRecruitingPhase 2 / Phase 32026-04-02NCT06581406
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCCBiliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, biliary tract cancer, biliary tract disorder, carcinoma, epithelial neoplasm, hepatocellular carcinoma, liver disorder, neoplasmRecruitingPhase 22026-04-02NCT05733598
Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid TumoursAdvanced Solid TumorActive, not recruitingPhase 12026-02-27NCT04735978
Study of RP2 Monotherapy and RP2 in Combination With Nivolumab in Patients With Solid TumorsDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Thoracic Neoplasms, Uveal Neoplasms, breast disorder, breast neoplasm, cancer, digestive system disorder, digestive system neoplasm, eye disorder, lung disorder, lung neoplasm, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, ocular cancer, primitive neuroectodermal tumor, respiratory system disorder, respiratory tract neoplasm, skin disorder, uveal disorder, uveal melanomaActive, not recruitingPhase 12026-02-27NCT04336241
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Non-Melanoma Skin Neoplasms, Skin and Connective Tissue Diseases, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, cutaneous melanoma, lung disorder, lung neoplasm, melanocytic neoplasm, melanoma, mismatch repair cancer syndrome 1, neoplasm, neuroendocrine neoplasm, non-small cell lung carcinoma, primitive neuroectodermal tumor, respiratory system disorder, respiratory tract neoplasm, skin disorder, skin neoplasmActive, not recruitingPhase 22026-02-13NCT03767348
A Study to Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, adenocarcinoma, carcinoma, epithelial neoplasm, hepatocellular carcinoma, liver disorder, melanocytic neoplasm, melanoma, metastatic melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasmRecruitingNot stated2026-01-12NCT06887348
Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin CancerNeoplasms by Histologic Type, carcinoma, epithelial neoplasm, neoplasm, skin squamous cell carcinoma, squamous cell carcinoma, squamous cell neoplasmActive, not recruitingPhase 22025-01-27NCT04050436