7 results · Page 1 of 1

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Phase 1 Study of HCB303 in Participants With Advanced MalignanciesAdvanced MalignanciesNot yet recruitingPhase 12026-10-05NCT07859228
A Phase I/II Trial of HCB101 in Combination With Pembrolizumab for Patients With Platinum-Refractory, Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (SirH&N Trial)Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, neoplasm, squamous cell carcinomaRecruitingPhase 1 / Phase 22026-07-06NCT07136545
Phase Ib/IIa Open-label Study, to Evaluate Safety, Tolerability, and Antitumor Activity of HCB101 in Combination With Multiple Agents in Subjects With Advanced Gastric or Gastro-esophageal (GEJ) AdenocarcinomaGC/GEJCNot yet recruitingPhase 1 / Phase 22026-07-02NCT07680569
An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced TumorsBone Diseases, Developmental, Camurati-Engelmann disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Hodgkins lymphoma, Neoplasms by Histologic Type, bone disorder, hereditary disease, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, musculoskeletal system disorder, neoplasm, osteochondrodysplasiaRecruitingPhase 12026-04-13NCT06487624
Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid TumorsSolid CancerActive, not recruitingPhase 1 / Phase 22026-02-04NCT06771622
A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological TumorsHemic and Lymphatic Diseases, Neoplasms by Histologic Type, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasmRecruitingPhase 12026-02-04NCT05892718
The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancercolorectal carcinomaRecruitingPhase 1 / Phase 22025-10-02NCT07204574