ALS Association
ALS Association
Explore linked clinical trials.8 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD | Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, psychiatric disorder, spinal cord disorder | Active, not recruiting | Phase 2 | 2026-08-20 | NCT04220021 | |
| Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS) | Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, communication disorder, language disorder, locked-in syndrome, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, palsy, proteostasis deficiencies, quadriplegia, speech disorder, spinal cord disorder | Not yet recruiting | Not applicable | 2026-07-13 | NCT07698496 | |
| Phenotype, Genotype & Biomarkers in ALS and Related Disorders | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Frontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, brain disorder, central nervous system disorder, central nervous system malformation, cognitive disorder, dementia, frontotemporal dementia, hereditary disease, hereditary motor and sensory neuropathy, hereditary spastic paraplegia, inherited neurodegenerative disorder, lateral sclerosis, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, progressive muscular atrophy, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, spinal muscular atrophy | Active, not recruiting | Not stated | 2026-06-15 | NCT02327845 | |
| A Study of Ranolazine in ALS | Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder | Recruiting | Phase 2 | 2026-06-08 | NCT06527222 | |
| Adenosine 2A Receptor Antagonism and AIH in ALS | Hypoxia, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Respiratory Aspiration, Signs and Symptoms, Signs and Symptoms, Respiratory, amyotrophic lateral sclerosis, respiratory system disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-03-27 | NCT05377424 | |
| The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study | Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, frontotemporal dementia with motor neuron disease, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder | Recruiting | Not stated | 2026-03-20 | NCT00317616 | |
| Clinical Research in ALS Study | Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder | Recruiting | Not stated | 2026-03-20 | NCT00136500 | |
| Metagenomic Characterization of the Intestinal Microbiota in ALS Patients and Association With Clinical Phenotypes | Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder | Not yet recruiting | Not stated | 2025-07-03 | NCT06771414 |