Lexicon Pharmaceuticals
Lexicon Pharmaceuticals
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Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy | Cardiomyopathy, Hypertrophic Obstructive, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Phase 3 | 2026-08-26 | NCT06481891 | |
| Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes | Nutritional and Metabolic Diseases, autoimmune disease, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, metabolic disease, type 1 diabetes mellitus | Active, not recruiting | Phase 1 / Phase 2 | 2026-06-15 | NCT05696366 | |
| Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes | Nutritional and Metabolic Diseases, autoimmune disease, cardiovascular disorder, diabetes mellitus, endocrine system disorder, glucose metabolism disease, heart disorder, heart failure, immune system disorder, metabolic disease, type 1 diabetes mellitus | Recruiting | Phase 2 | 2026-04-06 | NCT06435156 | |
| Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease | Chronic Disease, Diabetes Complications, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, autoimmune disease, cardiovascular disorder, chronic renal failure syndrome, diabetes mellitus, diabetic kidney disease, endocrine system disorder, glucose metabolism disease, heart disorder, heart failure, immune system disorder, kidney disorder, kidney failure, metabolic disease, type 1 diabetes mellitus, urinary system disorder | Recruiting | Phase 3 | 2026-03-24 | NCT06217302 | |
| CKM For Safe Use of SGLT2i in Type 1 Diabetes | Nutritional and Metabolic Diseases, autoimmune disease, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, metabolic disease, type 1 diabetes mellitus | Not yet recruiting | Phase 3 | 2025-10-08 | NCT07211802 | |
| Comparison of Antiplatelet Effects of Sotagliflozin to FDA-approved Antiplatelet Drugs | Platelet Function and Reactivity Tests | Recruiting | Early phase 1 | 2025-09-15 | NCT06933056 |