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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Natural History and Genotype-Phenotype Correlations in Mitochondrial LeukoencephalopathiesLeukoencephalopathies, Nutritional and Metabolic Diseases, brain disorder, central nervous system disorder, inborn mitochondrial metabolism disorder, metabolic disease, nervous system disorderRecruitingNot stated2026-10-09NCT07868796
Italian Trigeminal Autonomic Cephalalgias Assessment Studybrain disorder, central nervous system disorder, cluster headache syndrome, headache disorder, hemicrania continua, hypnic headache, nervous system disorder, paroxysmal Hemicrania, trigeminal autonomic cephalalgiaRecruitingNot stated2026-09-22NCT07812740
High-Density EEG-MEG-wearable EEG: Comparison of Quantitative Electroencephalographic Indicators as Neurophysiological Markers of Effectiveness of Mindfulness Therapy in Addition to Standard Treatment in Patients With High-frequency Episodic Migrainebrain disorder, central nervous system disorder, headache disorder, hypnic headache, migraine disorder, nervous system disorderRecruitingNot stated2026-09-01NCT06938178
Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cerebral Amyloid Angiopathy, Familial, Cerebral Small Vessel Diseases, Cognition Disorders, Cognitive Dysfunction, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Infarction, Necrosis, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, amyloidosis, brain disorder, brain infarction, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebral amyloid angiopathy, cerebral arterial disease, cerebral infarction, cerebrovascular disorder, cognitive disorder, dementia, hereditary amyloidosis, hereditary disease, inborn errors of metabolism, intracranial arterial disease, ischemic disease, metabolic disease, nervous system disorder, proteostasis deficiencies, psychiatric disorder, stroke disorder, vascular dementia, vascular disorderRecruitingNot stated2026-09-01NCT06933212
Home Rehabilitation as Continuity of Care in MSCNS demyelinating autoimmune disease, autoimmune disease, autoimmune disorder of the nervous system, demyelinating disease, immune system disorder, multiple sclerosis, nervous system disorderActive, not recruitingNot applicable2026-09-01NCT06699095
Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASILCerebral Small Vessel Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Infarction, Necrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, brain infarction, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebral arterial disease, cerebral infarction, cerebrovascular disorder, dementia, disease, hereditary disease, intracranial arterial disease, ischemic disease, nervous system disorder, stroke disorder, vascular dementia, vascular disorderRecruitingNot stated2026-08-31NCT06938100
Clinical Significance of Liquid Biopsy in Brain Tumor Patients: a 5-ALA Guided ApproachNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorActive, not recruitingNot stated2026-08-28NCT07420543
Epigenetic Profiling and Liquid Biopsy: Perspectives for Personalized Medicine in Meningioma Patients - MINDNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Nerve Tissue, central nervous system cancer, meningioma, neoplasm, nervous system disorder, tumor of meninges, vascular cancerActive, not recruitingNot stated2026-08-28NCT07282470
Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical ApproachesFrontotemporal Lobar Degeneration, Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, intracranial hypertension, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, pseudotumor cerebri, psychiatric disorder, spinal cord disorderActive, not recruitingNot stated2026-08-28NCT06856850
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body DiseaseLewy body dementia, Parkinson disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cognitive disorder, dementia, disease, familial cylindromatosis, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, psychiatric disorder, synucleinopathy, vascular disorderActive, not recruitingNot stated2026-08-28NCT06846658
Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project)Arterial Occlusive Diseases, Moyamoya disease, Nutritional and Metabolic Diseases, amyloidosis, brain disorder, cardiovascular disorder, carotid artery disorder, central nervous system disorder, cerebral amyloid angiopathy, cerebral arterial disease, cerebrovascular disorder, intracranial arterial disease, metabolic disease, nervous system disorder, proteostasis deficiencies, stroke disorder, vascular disorderRecruitingNot applicable2026-08-28NCT06714097
Cross-cultural Adaptation and Multicenter Validation of the Italian Versions of the Brief Evaluation of Receptive Aphasia (BERA) and SWallowing Assessment in Disorders of Consciousness (SWADOC)Aphasia, Wernicke, Consciousness Disorders, Craniocerebral Trauma, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, aphasia, brain disorder, brain injury, central nervous system disorder, cognitive disorder, communication disorder, injury, language disorder, nervous system disorder, nervous system injury, psychiatric disorder, speech disorderNot yet recruitingNot stated2026-07-17NCT07711119
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive VariablesAlzheimer disease, Cognition Disorders, Cognitive Dysfunction, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathyNot yet recruitingNot stated2026-06-11NCT07533084
RimegepAnt effectIvenesS and tolErability as Migraine Preventive TreatmentHeadache, Headache Disorders, Secondary, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, headache disorder, hypnic headache, migraine disorder, migraine with aura, migraine without aura, nervous system disorderRecruitingNot stated2026-06-11NCT06409832
Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy ComparedNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-04-23NCT07547163
Study for the Diagnosis and Treatment of Drug-resistant Focal Epilepsiesbrain disorder, central nervous system disorder, epilepsy, nervous system disorderRecruitingNot stated2026-04-01NCT06794606
Neurosurgical Outcome NetworkAneurysm, Arterial Occlusive Diseases, Cardiovascular Abnormalities, Chiari malformation type I, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniocerebral Trauma, Craniofacial Pain, Drug Resistant Epilepsy, Dyskinesias, Facial Pain, Hematoma, Hematoma, Epidural, Spinal, Hematoma, Subdural, Hemorrhage, Intracranial Hemorrhage, Traumatic, Intracranial Hemorrhages, Moyamoya disease, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Stomatognathic Diseases, Tremor, anxiety disorder, arteriovenous hemangioma/malformation, brain disorder, cardiovascular disorder, carotid artery disorder, central nervous system disorder, cerebral arterial disease, cerebrovascular disorder, cranial nerve neuropathy, depressive disorder, dystonic disorder, epilepsy, facial nerve disorder, facial neuralgia, hydrocephalus, injury, intracranial arterial disease, mouth disorder, movement disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, nervous system injury, neuralgia, neuromuscular disease, normal pressure hydrocephalus, obsessive-compulsive disorder, peripheral nervous system disorder, psychiatric disorder, subarachnoid hemorrhage, trigeminal nerve disorder, trigeminal neuralgia, vascular disorder, vascular malformationRecruitingNot stated2026-03-30NCT06724029
Multimodal Investigation of Cortico-Basal Ganglia-Thalamo-Cortical Network Dynamics in Dystonic Patients With Deep Brain StimulationDyskinesias, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system disorder, dystonic disorder, movement disorder, nervous system disorderRecruitingNot stated2026-03-30NCT06716983
SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA)Nutritional and Metabolic Diseases, amyloidosis, brain disorder, cardiovascular disorder, central nervous system disorder, cerebral amyloid angiopathy, cerebral arterial disease, cerebrovascular disorder, intracranial arterial disease, metabolic disease, nervous system disorder, proteostasis deficiencies, vascular disorderRecruitingNot stated2026-03-30NCT04204642
Italian NCL Registry: a Registry for NCL as an Integration Tool for Future Therapeutic StrategiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Neuronal Ceroid-Lipofuscinoses, Nutritional and Metabolic Diseases, hereditary disease, inborn errors of metabolism, inherited neurodegenerative disorder, lysosomal lipid storage disorder, metabolic disease, nervous system disorder, neurodegenerative diseaseRecruitingNot stated2026-03-27NCT06844877
This Three-year Observational Study Involves Patients of All Ages Undergoing Endovascular Treatment for Various Cerebral or Spinal Vascular Conditions. It Aims to Assess Pre- and Post-operative Clinical Conditions, Report Complications, and Identify Preoperative Indicators of Treatment Outcomes. PatAneurysm, brain aneurysm, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, intracranial arterial disease, nervous system disorder, vascular disorderRecruitingNot stated2026-03-27NCT06805721
Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)autonomic nervous system disorder, basal ganglia disorder, brain disorder, cardiovascular disorder, central nervous system disorder, hypotensive disorder, movement disorder, multiple system atrophy, nervous system disorder, primary dysautonomia, supranuclear palsy, progressive, 1, vascular disorderActive, not recruitingNot applicable2026-03-27NCT05792332
Toward Molecular Profiling of Parkinson's Disease in Easily Accessible Biological MatricesAlzheimer disease, Nutritional and Metabolic Diseases, Parkinson disease, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, dementia, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, proteostasis deficiencies, psychiatric disorder, synucleinopathy, tauopathyActive, not recruitingNot applicable2026-03-18NCT07480187
Studying Nerve Function and Structure in Charcot-Marie-Tooth Disease, Anti-MAG Neuropathy and CIDPCharcot-Marie-Tooth disease, Charcot-Marie-Tooth disease X-linked dominant 1, Charcot-Marie-Tooth disease type 1A, Charcot-Marie-Tooth disease type 4B2, Charcot-Marie-Tooth disease type 4D, Chronic Disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, central nervous system malformation, chronic inflammatory demyelinating polyradiculoneuropathy, demyelinating disease, hereditary disease, hereditary motor and sensory neuropathy, immune system disorder, inherited neurodegenerative disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, polyneuropathy, polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG, polyradiculoneuropathyRecruitingNot stated2026-03-10NCT07461896
Heart Rate Variability and Processed EEG Features as Predictors of Postoperative Outcomes After Cranial NeurosurgeryCranial NeurosurgeryRecruitingNot stated2026-03-10NCT07443072