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National Heart, Lung, and Blood Institute (NHLBI)

National Heart, Lung, and Blood Institute (NHLBI)

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label DevicesVentricular Outflow Obstruction, Ventricular Outflow Obstruction, Left, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosisNot yet recruitingNot applicable2026-10-09NCT07806149
Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 InhibitorB-cell chronic lymphocytic leukemia, Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, B-Cell, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoproliferative syndrome, neoplasmNot yet recruitingPhase 22026-10-09NCT07796373
Immune Dysregulation During Sepsis: A Natural History CohortInfections, Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sepsis, Shock, Systemic Inflammatory Response Syndrome, toxic shock syndromeNot yet recruitingNot stated2026-10-09NCT07735741
Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaDyslipidemias, Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, hyperlipidemia, hypertriglyceridemia, metabolic diseaseNot yet recruitingNot applicable2026-10-09NCT07715890
Remote Evaluation and Surveillance of Patients With Interstitial Lung Disease: Transforming ILD Care Delivery With Remote MonitoringFibrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, idiopathic pulmonary fibrosis, interstitial lung disease, lung disorder, pulmonary fibrosis, respiratory system disorderRecruitingNot applicable2026-10-09NCT07673237
EDEN Intracardiac Electrogram Recording and Classifying SystemVentricular ArrhythmiaEnrolling by invitationNot applicable2026-10-09NCT07137455
Polygenic Risk Score Implementation and Stratification for Managing Blood PressureArterial Occlusive Diseases, Disease Attributes, Genetic Risk Score, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, atherosclerotic cardiovascular disease, cardiovascular disorder, disease susceptibility, hypertensive disorder, inherited disease susceptibility, vascular disorderRecruitingNot applicable2026-10-09NCT06962488
Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesLung TransplantationRecruitingPhase 12026-10-09NCT06948097
VINTAGE (Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms) Using Commercial Off-The-Shelf (COTS) CathetersVentricular ArrhythmiaEnrolling by invitationNot applicable2026-10-09NCT06940752
Effect of Sacubitril-Valsartan on Cardiac Structure and FunctionCardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorderRecruitingPhase 32026-10-09NCT06693674
Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)cardiovascular disorder, heart disorder, heart failureEnrolling by invitationNot stated2026-10-09NCT06280820
Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)Nutritional and Metabolic Diseases, cardiovascular disorder, diabetes mellitus, endocrine system disorder, glucose metabolism disease, hypertensive disorder, metabolic disease, vascular disorderActive, not recruitingNot applicable2026-10-09NCT05524987
NHLBI-Emory Advanced Cardiac CT Reconstructioncardiovascular disorder, heart disorderNot yet recruitingNot stated2026-10-09NCT05372627
Technical Development of Cardiovascular Magnetic Resonance Imagingcardiovascular disorder, heart disorder, heart failureRecruitingNot stated2026-10-09NCT04927429
eCPAP Follow-up at School AgeFemale Urogenital Diseases and Pregnancy Complications, Obstetric Labor Complications, Obstetric Labor, Premature, Premature Birth, Urogenital Diseases, pregnancy disorderNot yet recruitingNot stated2026-10-08NCT07860931
Inspiratory Muscle Strength Training in Adults With Type 1 DiabetesNutritional and Metabolic Diseases, autoimmune disease, cardiovascular disorder, diabetes mellitus, endocrine system disorder, glucose metabolism disease, hypertensive disorder, immune system disorder, metabolic disease, type 1 diabetes mellitus, vascular disorderNot yet recruitingNot applicable2026-10-08NCT07859943
COPD Resources, Education, and Activity Designed for You StudyChronic Disease, Disease Attributes, Infections, Pathologic Processes, Pathological Conditions, Signs and Symptoms, bronchial disorder, bronchitis, chronic bronchitis, chronic obstructive pulmonary disease, lung disorder, obstructive lung disease, pulmonary emphysema, respiratory system disorder, respiratory tract infectious disorderRecruitingNot applicable2026-10-08NCT07125053
Peer Support for Adolescents and Emerging Adults With Sickle Cell PainCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Neurobehavioral Manifestations, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, agnosia, anemia, familial hemolytic anemia, hematologic disorder, hemolytic anemia, hereditary disease, inherited hemoglobinopathy, nervous system disorder, perceptual disorders, sickle cell diseaseRecruitingNot applicable2026-10-08NCT06374238
Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Sickle Cell Trait, anemia, familial hemolytic anemia, hematologic disorder, hemolytic anemia, hereditary disease, inherited hemoglobinopathy, sickle cell diseaseRecruitingPhase 12026-10-08NCT05904093
Natural History Study of CADASILbrain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, nervous system disorder, stroke disorder, vascular disorderRecruitingNot stated2026-10-08NCT05072483
Data Collection of Standard Care and Evaluation of NHLBI Patients and DonorsHemic and Lymphatic Diseases, hematologic disorder, neoplasmEnrolling by invitationNot stated2026-10-08NCT04450927
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy Volunteerscardiovascular disorderRecruitingPhase 12026-10-08NCT04216342
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, Undiagnosed Diseases, cardiovascular disorderRecruitingNot stated2026-10-08NCT02543996
Quantitative Measurement and Correlates of the Latent HIV Reservoir in Virally Suppressed UgandansHIVRecruitingNot stated2026-10-08NCT02154035
Spironolactone for Pulmonary Arterial Hypertensionlung disorder, pulmonary arterial hypertension, pulmonary hypertension, respiratory system disorderRecruitingPhase 22026-10-08NCT01712620