North American Consortium for Histiocytosis | ClinicalTrials HQ

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Trial	Conditions	Status	Phase	Updated	More info	NCT ID
Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders	Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, respiratory system disorder	Active, not recruiting	Phase 2	2026-06-23		NCT02425904
Use Of A Response-Adapted Ruxolitinib-Containing Regimen For The Treatment Of Hemophagocytic Lymphohistiocytosis	Disease Attributes, Hemic and Lymphatic Diseases, Lymphohistiocytosis, Hemophagocytic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, histiocytosis, lymphatic system disorder, non-Langerhans cell histiocytosis	Active, not recruiting	Phase 1 / Phase 2	2026-04-24		NCT04551131
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis	Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, histiocytosis, interstitial lung disease, lung disorder, lymphatic system disorder, respiratory system disorder	Active, not recruiting	Phase 2 / Phase 3	2026-04-09		NCT02205762
Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders	Erdheim-Chester disease, Hemic and Lymphatic Diseases, Histiocytosis, Langerhans-Cell, Neoplasms by Histologic Type, Skin and Connective Tissue Diseases, histiocytic sarcoma, histiocytosis, interstitial lung disease, juvenile xanthogranuloma, lung disorder, lymphatic system disorder, malignant histiocytosis, neoplasm, non-Langerhans cell histiocytosis, respiratory system disorder, sinus histiocytosis with massive lymphadenopathy, skin disorder	Recruiting	Phase 2	2025-09-18		NCT04079179