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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Phase II Study of SKB264 + SKB118 in Nsq-NSCLC After EGFR-TKI FailureNon-Squamous Non-Small Cell Lung CancerNot yet recruitingPhase 22026-10-02NCT07854509
Toripalimab Plus Sacituzumab Tirumotecan as Neoadjuvant Therapy for Resectable NSCLCNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmNot yet recruitingPhase 22026-09-15NCT07819578
SKB118 Injection in Advanced Solid TumorsAdvanced Solid TumorsRecruitingPhase 1 / Phase 22026-09-11NCT07586943
A Multicenter, Open-label, Phase II Umbrella Study to Evaluate the Efficacy and Safety of the Investigational Product in Participants With Advanced or Metastatic Pancreatic CancerDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, endocrine system disorder, malignant endocrine neoplasm, malignant pancreatic neoplasm, neoplasm, pancreas disorder, pancreatic neoplasmNot yet recruitingPhase 22026-09-10NCT07814066
A Randomized, Phase Ib, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of SKB575 (HBM7575) in Participants With AsthmaHypersensitivity, Immediate, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Respiratory Hypersensitivity, asthma, bronchial disorder, disease, immune system disorder, lung disorder, obstructive lung disease, respiratory system disorderRecruitingPhase 12026-09-10NCT07732023
A Phase II Study to Evaluate the Efficacy and Safety of SKB571 in Recurrent or Metastatic HNSCC ParticipantsHead and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, neoplasm, squamous cell carcinomaRecruitingPhase 22026-09-09NCT07668154
SKB565 for Injection in Advanced Solid TumorsAdvanced Solid TumorsRecruitingPhase 1 / Phase 22026-09-03NCT07545265
A Study of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer (NSCLC)Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 22026-09-02NCT07622186
SKB500 Combinations in Patients With Esophageal Squamous Cell CarcinomaDigestive System Diseases, Digestive System Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, carcinoma, digestive system disorder, digestive system neoplasm, epithelial neoplasm, esophageal disorder, esophageal squamous cell carcinoma, neoplasm, squamous cell carcinoma, squamous cell neoplasmRecruitingPhase 22026-08-26NCT07700667
Phase II Study of Sacituzumab Tirumotecan in Combination With Osimertinib for Neoadjuvant Treatment in Patients With Resectable Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 22026-08-20NCT07329322
Study of SKB103 in HER2-negative Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderNot yet recruitingPhase 1 / Phase 22026-08-19NCT07774624
SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancernon-small cell lung carcinomaRecruitingPhase 22026-08-12NCT07697586
Sacituzumab Tirumotecan in Participants With Locally Advanced or Metastatic Thymic CarcinomaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Thymus Neoplasms, lymphatic system disorder, mixed neoplasm, neoplasm, thymomaRecruitingPhase 22026-08-12NCT07324629
A Study of SKB571 in Participants With Gastrointestinal TumorsDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, neoplasmRecruitingPhase 22026-08-04NCT07564466
A Phase II Clinical Study of SKB571 as Monotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With MET AbnormalitiesNon-small Lung CancerRecruitingPhase 22026-07-30NCT07308106
Sacituzumab Tirumotecan in Previously Treated TROP2-Positive Advanced Biliary Tract CancerBiliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, biliary tract disorder, neoplasmNot yet recruitingPhase 22026-07-14NCT07701122
A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmActive, not recruitingPhase 32026-07-10NCT06670196
A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmActive, not recruitingPhase 32026-07-08NCT06711900
Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OCAdnexal Diseases, Carcinoma, Ovarian Epithelial, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, carcinoma, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, malignant endocrine neoplasm, neoplasm, ovarian cancer, ovarian disorderActive, not recruitingPhase 22026-06-01NCT07341100
SKB315 in Combination Therapy in Patients With Advanced or Metastatic GC/ GEJ Adenocarcinomagastroesophageal junction adenocarcinomaNot yet recruitingPhase 22026-05-27NCT07609667
SKB103 for Injection in Advanced Solid TumorsAdvanced Solid TumorsRecruitingPhase 1 / Phase 22026-05-18NCT07459998
A Study of SKB518 as Monotherapy or Combination Therapy in Patients With Advanced Gynecological Malignant TumorsAdvanced Gynecological MalignanciesRecruitingPhase 22026-05-12NCT07448922
A Phase II Study of SKB571 in Patients With Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 22026-05-12NCT07230405
SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 22026-05-12NCT05351788
A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis ParticipantsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypersensitivity, Immediate, Skin Diseases, Eczematous, Skin and Connective Tissue Diseases, atopic eczema, dermatitis, hereditary disease, hereditary skin disorder, immune system disorder, skin disorderRecruitingPhase 12026-05-08NCT07488065