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Congressionally Directed Medical Research Programs

Congressionally Directed Medical Research Programs

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-10-09NCT07076498
Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory FailureLung Injury, acute lung injury, lung disorder, respiratory system disorderNot yet recruitingPhase 22026-10-08NCT07779642
Vestibular Rehabilitation App for Adults With Dizziness Related to mTBIBrain Concussion, Brain Injuries, Traumatic, Concussion, Mild, Craniocerebral Trauma, Dizziness, Head Injuries, Closed, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, Wounds, Nonpenetrating, brain disorder, brain injury, central nervous system disorder, injury, nervous system disorder, nervous system injuryRecruitingNot applicable2026-10-08NCT06222450
Deployment of a Novel National Institute of Neurological Disorders and Stroke Clinical, Biomarker, Imaging, and Modifiers (CBI-M) Classification Framework for Emergency Department Patients With Glasgow Coma Scale 15 Traumatic Brain Injury (PIONEER-Prognosis)Brain Injuries, Traumatic, Craniocerebral Trauma, brain disorder, brain injury, central nervous system disorder, injury, nervous system disorder, nervous system injuryNot yet recruitingNot stated2026-10-07NCT07858266
Social Determinants of Migrant Health Factors Impacting Prostate Cancer Care and Survivorship Among Sub-Saharan African and Caribbean Immigrant MenGenital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate carcinoma, prostate disorderEnrolling by invitationNot stated2026-10-07NCT06472817
Monitoring, Detoxifying, and Rebalancing Metals During Acute Myeloid Leukemia (AML) Therapy, a Phase 2 Randomized StudyHemic and Lymphatic Diseases, Neoplasms by Histologic Type, acute myeloid leukemia, hematologic disorder, leukemia, myeloid leukemia, neoplasmRecruitingPhase 22026-10-06NCT06811233
Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade GliomaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroepithelial neoplasm, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder, primitive neuroectodermal tumorNot yet recruitingPhase 22026-10-05NCT07521657
LMN-201 for Prevention of C. Difficile Infection RecurrenceBacterial Infections and Mycoses, Clostridium difficile Infections, Clostridium infectious disease, Infections, bacterial infectious disease, gram-positive bacterial infectionsActive, not recruitingPhase 2 / Phase 32026-10-05NCT05330182
Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord InjuryDigestive System Diseases, Fecal Incontinence, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system disorder, digestive system disorder, injury, intestinal disorder, nervous system disorder, nervous system injury, palsy, paraplegia, quadriplegia, rectal disorder, spinal cord disorder, spinal cord injuryRecruitingNot applicable2026-10-01NCT05626816
Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black MenGenital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate carcinoma, prostate disorderRecruitingNot applicable2026-09-29NCT06541210
SAINT in Postpartum Depression (PPD)Female Urogenital Diseases and Pregnancy Complications, Urogenital Diseases, depressive disorder, mood disorder, postpartum depression, pregnancy disorder, psychiatric disorder, puerperal disorderRecruitingNot applicable2026-09-28NCT07210255
A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black MenGenital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate carcinoma, prostate disorderRecruitingNot applicable2026-09-25NCT07126548
Pregnenolone to Target Concurrent PTSD and Stress Induced Alcohol Use in Veterans: A Dose Finding StudyChemically-Induced Disorders, Stress Disorders, Traumatic, acute stress disorder, alcohol-related disorders, post-traumatic stress disorder, psychiatric disorder, substance-related disorderNot yet recruitingPhase 22026-09-21NCT06580444
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient StudyChemically-Induced Disorders, Stress Disorders, Traumatic, acute stress disorder, alcohol-related disorders, post-traumatic stress disorder, psychiatric disorder, substance-related disorderRecruitingPhase 12026-09-21NCT06335407
Targeted Plasticity Therapy for PTSDStress Disorders, Traumatic, acute stress disorder, combat disorder, post-traumatic stress disorder, psychiatric disorderRecruitingNot applicable2026-09-16NCT06266364
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord InjuryInsulin Resistance, Nutritional and Metabolic Diseases, central nervous system disorder, glucose metabolism disease, hyperinsulinism, injury, metabolic disease, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injuryRecruitingPhase 12026-09-15NCT07384052
mSCI: Mobile Health App for Veterans With SCI and Caregiverscentral nervous system disorder, injury, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injuryRecruitingNot stated2026-09-15NCT07269977
Adaptation and Feasibility Testing of a Fatigue Intervention in Adults With TBIBrain Injuries, Traumatic, Craniocerebral Trauma, brain disorder, brain injury, central nervous system disorder, injury, nervous system disorder, nervous system injuryNot yet recruitingNot applicable2026-09-09NCT07798245
Early BOTOX After Spinal Cord InjuryFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Urinary Bladder, Neurogenic, Urogenital Diseases, autonomic dysreflexia, autonomic nervous system disorder, central nervous system disorder, injury, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injury, urinary bladder disorder, urinary system disorderEnrolling by invitationEarly phase 12026-09-09NCT06793683
Confirmatory Trial for Alleviating Fatigue in Multiple SclerosisCNS demyelinating autoimmune disease, Fatigue, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, demyelinating disease, immune system disorder, multiple sclerosis, nervous system disorderEnrolling by invitationNot applicable2026-09-04NCT06441617
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterizationcentral nervous system disorder, injury, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injuryRecruitingPhase 1 / Phase 22026-09-03NCT06596291
A Study of Oral MBQ-167 in Participants With Advanced Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingPhase 12026-08-31NCT06075810
Prosthetic Limb Movement Feedback for Upper and Lower Extremity AmputeesAmputation; Prosthesis UserEnrolling by invitationNot applicable2026-08-26NCT03135847
Supported Online Self-Help for Veterans With Depression in Primary Caredepressive disorderNot yet recruitingNot applicable2026-08-24NCT07781228
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic TraumaRib Fractures, Thoracic Injuries, bone fracture, injuryEnrolling by invitationNot applicable2026-08-24NCT06069154