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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT)Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-10-07NCT07796061
A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset EpilepsyFocal Epilepsy With Secondary Generalization; Partial Seizures With Secondary GeneralizationActive, not recruitingNot applicable2026-10-07NCT03417297
MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal NeuralgiaStomatognathic Diseases, cranial nerve neuropathy, facial nerve disorder, facial neuralgia, mouth disorder, nervous system disorder, trigeminal nerve disorder, trigeminal neuralgiaActive, not recruitingNot applicable2026-07-20NCT04579692
Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorderActive, not recruitingPhase 12026-07-14NCT07193953
Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated GlioblastomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-05-06NCT07343986
LIFU for Chronic PainChronic Pain, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and SymptomsEnrolling by invitationNot applicable2026-03-31NCT06628180
Ultrasound Neuromodulation in Essential Tremorcentral nervous system disorder, essential tremor, movement disorder, nervous system disorderRecruitingNot applicable2026-03-06NCT06610877
MRgFUS Pallidotomy for the Treatment of Task Specific Focal Hand Dystonia (TSFD)dystonia, focal, task-specificRecruitingNot applicable2026-02-27NCT06367608
Stereotactic MRI-guided Focused Ultrasound MesencephalotomyCancer Pain, Head and Neck Neoplasms, Neoplasms by Site, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, neoplasmRecruitingNot applicable2026-02-12NCT07405645
FUS Etoposide for DMGNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, diffuse midline glioma, H3 K27M-mutant, epithelial neoplasm, glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-01-28NCT05762419
Use of the Neurolyser XR for the Treatment of Low Back Pain Related to SacroiliitisSacroiliitis, arthritic joint disease, arthropathy, musculoskeletal system disorderRecruitingNot applicable2025-05-22NCT06053255
Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid OsteomasNeoplasms by Histologic Type, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, connective tissue neoplasm, neoplasm, osteoid osteoma, osteomaRecruitingPhase 32025-02-19NCT02923011
Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomycentral nervous system disorder, essential tremor, movement disorder, nervous system disorderActive, not recruitingNot applicable2021-02-24NCT03560622