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Translational Breast Cancer Research Consortium

Translational Breast Cancer Research Consortium

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Niraparib + Dostarlimab In BRCA Mutated Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 22026-09-24NCT04584255
Evolutionary Clinical Trial for Novel Biomarker-Driven TherapiesNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaRecruitingPhase 22026-09-18NCT07340541
PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)Neoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, hormone receptor-positive breast cancer, neoplasm, skin disorderRecruitingPhase 22026-08-26NCT07222215
TReatment of ADC-Refractory Breast CancEr With Dato-DXd or T-DXd: TRADE DXdNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingPhase 22026-08-26NCT06533826
ETHAN - ET for Male BCNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, hormone receptor-positive breast cancer, male breast carcinoma, neoplasm, skin disorderRecruitingPhase 22026-08-24NCT05501704
Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 22026-08-13NCT01937117
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingPhase 22026-08-06NCT06439693
STOP-HER2: Stopping Trastuzumab in HER2+ MBCNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 22026-08-06NCT05721248
Sac-TMT for Active TNBC Brain MetastasesNeoplasms by Site, Skin and Connective Tissue Diseases, brain disorder, breast disorder, breast neoplasm, central nervous system cancer, central nervous system disorder, neoplasm, nervous system disorder, skin disorder, triple-negative breast carcinomaNot yet recruitingPhase 22026-07-24NCT07458113
Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD)Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaActive, not recruitingPhase 22026-07-13NCT04443348
QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast CancerHER2-positive Metastatic Breast CancerRecruitingNot stated2026-07-08NCT06551116
Male Breast Cancer: Understanding the Biology for Improved Patient CareNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingNot stated2026-05-12NCT01101425
PREDICT-RD: ctDNA Surveillance in TNBC With Residual DiseaseNeoplasm, Residual, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaRecruitingPhase 22026-04-22NCT07069595
Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, invasive breast carcinoma, neoplasm, skin disorder, triple-negative breast carcinomaActive, not recruitingPhase 22026-04-17NCT03971409
Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast CancerNeoplasm, Residual, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingPhase 22026-04-09NCT04841148
Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast CancerHER2 positive breast carcinoma, Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 1 / Phase 22026-01-23NCT03368729
Prospective Registry of ADC as First- and Second-line Treatment for Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaRecruitingNot stated2025-12-18NCT06774027
MARGetuximab Or Trastuzumab (MARGOT)Neoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 22025-11-18NCT04425018
Extension Study of Lapatinib Plus Herceptin With or Without Endocrine TherapyNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 22025-03-12NCT00999804