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Children's National Research Institute

Children's National Research Institute

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
UltraTrac Clinical Pilot StudyHemodynamic MonitoringNot yet recruitingNot stated2026-10-08NCT07864714
Study of Mycobacterial InfectionsActinomycetales infectious disease, Bacterial Infections and Mycoses, Infections, Mycobacterium Infections, Nontuberculous, Mycobacterium avium complex disease, bacterial infectious disease, gram-positive bacterial infections, mycobacterial infectious diseaseRecruitingNot stated2026-10-08NCT00018044
Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT)Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-10-07NCT07796061
Cooperative Assessment of Late Effects for SCD Curative TherapiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Male Urogenital Diseases, Urogenital Diseases, anemia, cardiovascular disorder, familial hemolytic anemia, heart disorder, hematologic disorder, hemolytic anemia, hereditary disease, inherited hemoglobinopathy, kidney disorder, lung disorder, respiratory system disorder, sickle cell disease, urinary system disorderActive, not recruitingNot stated2026-10-06NCT05153967
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Acid-Base Imbalance, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cerebral Small Vessel Diseases, Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Ear Diseases, MELAS syndrome, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, Tremor, acidosis disorder, anxiety disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, cognitive disorder, dystonic disorder, eye disorder, headache disorder, hearing disorder, hearing loss disorder, hereditary disease, hypnic headache, inborn errors of metabolism, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, lactic acidosis, metabolic disease, migraine disorder, mitochondrial encephalomyopathy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, otorhinolaryngologic disease, psychiatric disorder, vascular disorder, vision disorder, visual epilepsyNot yet recruitingPhase 1 / Phase 22026-10-05NCT06792500
Ultra-Rapid Profiling and Drug Screening for Treatment Selection in Patients With Relapsed or Recurrent Rare Brain TumorsBCOR ITD sarcoma, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, central nervous system cancer, central nervous system disorder, central nervous system sarcoma, epithelial neoplasm, mesenchymal cell neoplasm, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumorNot yet recruitingNot applicable2026-10-01NCT07851636
Boosting Resources for Tracheostomy Care at HomeCaregiver Burden; TracheostomyEnrolling by invitationNot applicable2026-09-30NCT06283953
Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, anemia, familial hemolytic anemia, hematologic disorder, hemolytic anemia, hereditary disease, inherited hemoglobinopathy, sickle cell disease, thalassemiaRecruitingEarly phase 12026-09-28NCT06313398
Cool Prime Comparative Effectiveness Study for Mild HIEHypoxia, Hypoxia, Brain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, brain disorder, brain hypoxia - ischemia, brain ischemia, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, nervous system disorder, vascular disorderRecruitingNot stated2026-09-25NCT04621279
Study of Proteus Syndrome and Related Congenital DisordersAbnormalities, Multiple, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cowden disease, Limb Deformities, Congenital, Musculoskeletal Abnormalities, Neoplasms, Multiple Primary, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Proteus syndrome, bone disorder, hamartoma, hereditary endocrine growth disease, musculoskeletal system disorder, neoplasmRecruitingNot stated2026-09-22NCT00001403
Unstuck-Early Childhood Effectiveness & Implementation Trialdevelopmental disability, neurodevelopmental disorder, psychiatric disorderNot yet recruitingNot applicable2026-09-21NCT07832344
Impact of AI Care Summaries on Caregiver ComprehensionComprehension; Health Literacy; Patient SatisfactionRecruitingNot applicable2026-09-21NCT07831018
Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Status Epilepticus, nervous system disorder, visual epilepsyRecruitingPhase 32026-09-17NCT06907173
EMPoWER Study - Strengths-based Behavioral Intervention for Youth With Type 1 DiabetesNutritional and Metabolic Diseases, autoimmune disease, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, metabolic disease, type 1 diabetes mellitusActive, not recruitingNot applicable2026-09-14NCT06014879
NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain TumorsNeoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, mixed neoplasm, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumor, rhabdoid tumorRecruitingPhase 12026-09-09NCT07664176
BBD Longitudinal Study of Osteogenesis ImperfectaBone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, brittle bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta, osteogenesis imperfecta type 5RecruitingNot stated2026-09-01NCT02432625
Pre-pubertal Low Dose Transdermal Estradiol in Turner SyndromeAdnexal Diseases, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Sex Chromosome Disorders, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, cardiovascular disorder, chromosomal disorder, congenital heart disease, disorder of sexual differentiation, endocrine system disorder, female reproductive system disorder, gonadal disorder, gonadal dysgenesis, heart disorder, hereditary disease, ovarian disorder, primary ovarian failure, sex chromosome disorder of sex developmentNot yet recruitingPhase 22026-08-25NCT07784582
Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling CathetersFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Urinary Bladder, Neurogenic, Urogenital Diseases, nervous system disorder, urinary bladder disorder, urinary system disorderActive, not recruitingPhase 22026-08-21NCT04323735
Multi-antigen T Cell Infusion Against Neuro-oncologic DiseaseNeoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, neoplasm, nervous system disorderActive, not recruitingPhase 12026-08-14NCT03652545
Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic MalignanciesDisease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, acute myeloid leukemia, hematologic disorder, hematopoietic and lymphoid system neoplasm, leukemia, myeloid leukemia, neoplasmRecruitingPhase 12026-08-14NCT02203903
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ewing sarcoma, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Myosarcoma, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Urogenital Diseases, Urogenital Neoplasms, Wilms tumor, benign urinary system neoplasm, connective tissue neoplasm, epithelial neoplasm, hereditary disease, hereditary neoplastic syndrome, kidney cancer, kidney disorder, mixed neoplasm, myomatous neoplasm, neoplasm, neuroblastoma, neuroepithelial neoplasm, osteosarcoma, primitive neuroectodermal tumor, rhabdomyosarcoma, sarcoma, urinary system disorderRecruitingPhase 12026-08-13NCT07172958
Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With MedulloblastomaNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, epithelial neoplasm, glioma, medulloblastoma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 12026-08-07NCT06514898
International Rare Brain Tumor RegistryBCOR ITD sarcoma, Disease Attributes, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, astroblastoma, central nervous system sarcoma, epithelial neoplasm, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingNot stated2026-08-07NCT05697874
T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell TransplantationInfections, viral infectious diseaseActive, not recruitingPhase 12026-08-07NCT03180216
Pupillary Dilation Reflex in Healthy VolunteersHealthy ParticipantsRecruitingNot stated2026-08-04NCT07746167