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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Study of AK157D1 for Injection in Advanced Solid TumorsAdvanced Solid TumorsNot yet recruitingPhase 12026-09-29NCT07847281
Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ AdenocarcinomaDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, digestive system disorder, digestive system neoplasm, gastric neoplasm, neoplasm, stomach disorderRecruitingPhase 32026-09-29NCT07700979
A Study to Evaluate the Efficacy and Safety of AK139 in Participants With Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis With Nasal Polyps (CRSwNP)Not yet recruitingPhase 22026-08-10NCT07755371
SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal CancerDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal cancer, rectal disorder, rectal neoplasmRecruitingPhase 22026-08-07NCT07162714
A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Non-Small Cell Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 1 / Phase 22026-07-29NCT07623356
AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLCResectable Non-small Cell Lung CancerActive, not recruitingPhase 22026-07-29NCT05247684
Phase III Study of AK112 for NSCLC PatientsNon-Squamous Non-small Cell Lung CancerActive, not recruitingPhase 32026-07-28NCT06396065
A Phase II Study of AK146D1 Combined With AK112 in Advanced Breast CancerAdvanced Breast CancerRecruitingPhase 22026-07-22NCT07591090
A Phase II Study of AK146D1 in Combination With AK112 in Advanced Non-Small Cell Lung CancerAdvanced Non Small Cell Lung Cancer (NSCLC)RecruitingPhase 22026-07-14NCT07669779
A Phase II Study of AK146D1 Mono or Combined With AK112 in Advanced Urothelial CarcinomaNeoplasms by Histologic Type, carcinoma, epithelial neoplasm, neoplasm, transitional cell carcinomaNot yet recruitingPhase 22026-06-09NCT07636772
Anlotinib+Cadonilimab+PULSAR in Advanced Biliary Tract CancerBiliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, biliary tract cancer, biliary tract disorder, neoplasmActive, not recruitingPhase 22026-06-09NCT07635290
A Study to Evaluate the PK Similarity of AK104 in Healthy Chinese Male ParticipationsHealthy Male Adults ParticipantsNot yet recruitingPhase 12026-06-01NCT07619001
A Phase I Clinical Study of AK150 in Advanced Malignant Solid TumorAdvanced Malignant Solid TumorsNot yet recruitingPhase 12026-05-05NCT07566247
A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorderNot yet recruitingPhase 1 / Phase 22026-04-30NCT07560124
A Long-term Follow-up Study of Subjects Enrolled in Clinical Trials of Cadonilimab (AK104)Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, digestive system disorder, digestive system neoplasm, gastric neoplasm, neoplasm, stomach disorderRecruitingNot stated2026-04-23NCT07547787
A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid TumorsAdvanced Solid TumorsActive, not recruitingPhase 1 / Phase 22026-04-23NCT05951608
Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon CancerMSI-H/dMMR Colorectal Cancer; Resectable Colon CancerRecruitingPhase 32026-04-22NCT07412613
Ivonescimab in Combination With Docetaxel in Advanced Non-Small Cell Lung CancerNeoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 32026-04-09NCT06928389
A Study to Evaluate the Efficacy and Safety of AK139 in Patients With Moderate-to-severe Atopic DermatitisModerate-to-Severe Atopic DermatitisNot yet recruitingPhase 22026-03-30NCT07502222
Study of AK119 Combined With AK112 in Patients With Advanced Solid TumorsSolid Tumor, AdultRecruitingPhase 1 / Phase 22026-03-18NCT05689853
A Phase II Clinical Study of AK104/AK112 in Combination With TT-00420 Tablet for Advanced HCC.Digestive System Diseases, Digestive System Neoplasms, Liver Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, carcinoma, epithelial neoplasm, hepatocellular carcinoma, liver disorder, neoplasmRecruitingPhase 22026-03-16NCT07052253
AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaRecruitingPhase 32026-03-16NCT06767527
A Study of AK117/AK112 in Metastatic Triple-Negative Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaActive, not recruitingPhase 22026-03-16NCT05227664
A Study to Evaluate the PK Similarity of AK112 in Healthy Chinese Male SubjectsHealthy Male SubjectsActive, not recruitingPhase 12026-03-09NCT07340476
ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)Neoplasm, Residual, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 22026-03-09NCT06951646