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National Center for Advancing Translational Sciences (NCATS)

National Center for Advancing Translational Sciences (NCATS)

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Depression (Trial 2 of 3)In-person Visits; Remote Visits; Remote vs. In-PersonNot yet recruitingNot applicable2026-10-09NCT07854301
In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE TrialFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Non-Muscle Invasive Bladder Neoplasms, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, carcinoma, epithelial neoplasm, neoplasm, urinary bladder disorder, urinary bladder neoplasm, urinary system disorderRecruitingPhase 1 / Phase 22026-10-08NCT06704191
Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma CellsNeoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), epithelial neoplasm, glioblastoma, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 1 / Phase 22026-10-08NCT06059690
Biomarkers in Friedreich's AtaxiaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Friedreich ataxia, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spinocerebellar Degenerations, atactic disorder, non-human animal, brain disorder, central nervous system disorder, cerebellar disorder, hereditary disease, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, spinal cord disorderRecruitingNot stated2026-10-06NCT02497534
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)Acid-Base Imbalance, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cerebral Small Vessel Diseases, Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Ear Diseases, MELAS syndrome, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, Tremor, acidosis disorder, anxiety disorder, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, cognitive disorder, dystonic disorder, eye disorder, headache disorder, hearing disorder, hearing loss disorder, hereditary disease, hypnic headache, inborn errors of metabolism, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, lactic acidosis, metabolic disease, migraine disorder, mitochondrial encephalomyopathy, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, otorhinolaryngologic disease, psychiatric disorder, vascular disorder, vision disorder, visual epilepsyNot yet recruitingPhase 1 / Phase 22026-10-05NCT06792500
Investigating Metabolic and Psychological Adaptations in a Clinical TrialBody Weight, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, diabetes mellitus, endocrine system disorder, glucose metabolism disease, metabolic disease, nutritional disorder, obesity disorder, overnutrition, type 2 diabetes mellitusActive, not recruitingNot applicable2026-10-02NCT06800794
Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy InfantsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, disease susceptibility, hereditary disease, inherited disease susceptibilityActive, not recruitingNot applicable2026-10-02NCT05161169
Prevention of Ototoxicity in NTM Patients Treated With IV AmikacinChemically-Induced Disorders, Drug-Induced Ototoxicity, Drug-Related Side Effects and Adverse Reactions, Ear Diseases, Neurologic Manifestations, Ototoxicity, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Sensation Disorders, Signs and Symptoms, hearing disorder, hearing loss disorder, injury, nervous system disorder, otorhinolaryngologic disease, radiation injuryRecruitingPhase 22026-10-01NCT05730283
Ketamine & Crisis Response Plan for Suicidal Ideation in the EDDisease Attributes, Emergencies, Pathologic Processes, Pathological Conditions, Signs and SymptomsRecruitingPhase 2 / Phase 32026-09-30NCT05696691
A Fully Remote Feasibility Trial of Phenylbutyrate for SLC6A1-Related DisordersEpilepsies, Myoclonic, Epilepsy, Generalized, Epileptic Syndromes, brain disorder, central nervous system disorder, epilepsy, nervous system disorderRecruitingPhase 22026-09-29NCT07847918
Music Therapy to Improve Dental Procedure Tolerance and Reduce Distress in Adults With Intellectual and Developmental DifferencesDental Anxiety; Intellectual and Developmental DifferencesNot yet recruitingNot applicable2026-09-25NCT07806201
A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older AdultsLethargy, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nervous system disorderRecruitingNot applicable2026-09-25NCT06919094
fMRI in Postural Tachycardia Syndromeautonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomiaActive, not recruitingNot applicable2026-09-24NCT04137757
Nutrition for Precision Health, Powered by the All of UsDietary Habits; Health; NutritionRecruitingNot applicable2026-09-23NCT05701657
Digital Mind Body Intervention Among Black and Hispanic Patients Living With Inflammatory Bowel DiseaseCrohn disease, Digestive System Diseases, colitis, colonic disorder, digestive system disorder, gastroenteritis, inflammatory bowel disease, intestinal disorder, ulcerative colitisNot yet recruitingNot applicable2026-09-14NCT06510296
A Home-Based Exercise Intervention (CAREFit-BMT) in Improving Heart Function Among Patients With High Risk Acute Myeloid Leukemia Undergoing Stem Cell TransplantHemic and Lymphatic Diseases, Neoplasms by Histologic Type, acute myeloid leukemia, hematologic disorder, leukemia, myeloid leukemia, neoplasmRecruitingNot applicable2026-09-11NCT07616921
Feasibility of a First-Line Physical Activity Intervention After Strokebrain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, hemorrhagic stroke, ischemic stroke, nervous system disorder, stroke disorder, vascular disorderActive, not recruitingNot applicable2026-09-10NCT06679803
Personalized Perioperative Analgesia Platform (PPAP) for Cesarean SectionCesarean Section Complications; Opioid UseRecruitingNot applicable2026-09-10NCT05380531
Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)Polymerase proofreading-related adenomatous polyposisRecruitingNot applicable2026-09-10NCT05367609
A Decision Support Tool for Pancreatic Cancer Screening -Aim 2Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, endocrine system disorder, malignant endocrine neoplasm, malignant pancreatic neoplasm, neoplasm, pancreas disorder, pancreatic neoplasmNot yet recruitingNot applicable2026-09-09NCT07808671
Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional HypoxemiaChronic Disease, Disease Attributes, Hypoxemia, Hypoxia, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, chronic obstructive pulmonary disease, interstitial lung disease, lung disorder, obstructive lung disease, respiratory system disorderEnrolling by invitationNot applicable2026-09-09NCT07512687
Improving Outcomes for Early Postpartum Mothers in Outpatient MOUD TreatmentParenting; Perinatal Substance Use; Substance Use TreatmentRecruitingNot applicable2026-09-09NCT07071766
Investigating Basal Ganglia-Cortical Physiology During Sleep and Its Modulation by Adaptive Deep Brain Stimulation in Parkinson DiseaseParkinson disease, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, synucleinopathyActive, not recruitingNot applicable2026-09-08NCT07808346
Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating Mutationsimmune system disorder, inborn error of immunityNot yet recruitingPhase 1 / Phase 22026-09-08NCT07670156
Aim 3: Pilot Study of a Serious Game to Promote Transition Readiness SkillsCardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorderActive, not recruitingNot applicable2026-09-08NCT07042334