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National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Pain Phenotyping of Rheumatic Diseases - An Observational StudyAxial Spondyloarthritis, Infections, Neuroinflammatory Diseases, Sjogren syndrome, Skin and Connective Tissue Diseases, Spondylarthritis, Spondylarthropathies, Stomatognathic Diseases, Xerostomia, ankylosing spondylitis, ankylosis, arthritic joint disease, arthropathy, autoimmune disease, autoimmune disorder of the nervous system, bone disorder, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system infectious disorder, central nervous system lupus, central nervous system vasculitis, cerebrovascular disorder, connective tissue disorder, dry eye syndrome, encephalitis, eye disorder, immune system disorder, lacrimal apparatus disorder, meningitis, meningoencephalitis, mouth disorder, musculoskeletal system disorder, nervous system disorder, rheumatic disorder, rheumatoid arthritis, salivary gland disorder, spondylitis, systemic lupus erythematosus, vascular disorder, vasculitis, vertebral column disorder, viral infection of central nervous systemNot yet recruitingNot stated2026-10-09NCT07829497
Study of Systemic Lupus ErythematosusFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, nephritis, systemic lupus erythematosus, urinary system disorderRecruitingNot stated2026-10-09NCT00001372
Combined Anabolic TherapyBone Diseases, Metabolic, Nutritional and Metabolic Diseases, bone disorder, metabolic disease, musculoskeletal system disorder, osteoporosisRecruitingPhase 42026-10-08NCT06558188
Frequency and Complications of Major Orthopedic Procedures in Medicare BeneficiariesAxial Spondyloarthritis, Skin and Connective Tissue Diseases, Spondylarthritis, Spondylarthropathies, ankylosing spondylitis, ankylosis, arthritic joint disease, arthropathy, autoimmune disease, bone disorder, connective tissue disorder, immune system disorder, musculoskeletal system disorder, rheumatic disorder, rheumatoid arthritis, spondylitis, vertebral column disorderActive, not recruitingNot stated2026-10-08NCT02281747
Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic VasculitisAortic Arch Syndromes, Cartilage Diseases, Skin and Connective Tissue Diseases, Takayasu arteritis, anti-neutrophil cytoplasmic antibody-associated vasculitis, aortic disorder, arteritis, autoimmune disease, autoimmune disorder of the nervous system, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system vasculitis, cerebrovascular disorder, connective tissue disorder, immune system disorder, musculoskeletal system disorder, necrotizing vasculitis, nervous system disorder, polyarteritis nodosa, relapsing polychondritis, skin disorder, skin vascular disease, temporal arteritis, vascular disorder, vasculitisRecruitingNot stated2026-10-08NCT02257866
Natural History and Development of SpondyloarthritisAxial Spondyloarthritis, Sacroiliitis, Skin and Connective Tissue Diseases, Spondylarthritis, Spondylarthropathies, ankylosing spondylitis, ankylosis, arthritic joint disease, arthropathy, autoimmune disease, bone disorder, connective tissue disorder, immune system disorder, juvenile idiopathic arthritis, musculoskeletal system disorder, rheumatic disorder, spondylitis, vertebral column disorderRecruitingNot stated2026-10-08NCT01422694
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related ConditionsBody Temperature Changes, Fever, Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Skin and Connective Tissue Diseases, adult-onset Still disease, arthritic joint disease, arthropathy, autoimmune disease, autoinflammatory syndrome, connective tissue disorder, immune system disorder, musculoskeletal system disorder, rheumatic disorder, rheumatoid arthritisRecruitingNot stated2026-10-06NCT03510442
Self-regulation of Real-time fMRI Brain Activity in Chronic Painfibromyalgia, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, rheumatic disorderRecruitingNot applicable2026-10-05NCT07023523
Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic DiseaseBone Diseases, Developmental, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hyperostosis, musculoskeletal system disorder, osteochondrodysplasia, osteosclerosis, rheumatic disorderRecruitingNot stated2026-10-02NCT02504879
Studies of the Natural History of Rheumatic DiseasesSkin and Connective Tissue Diseases, arthritic joint disease, arthropathy, connective tissue disorder, musculoskeletal system disorder, rheumatic disorderRecruitingNot stated2026-10-02NCT00024479
Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by QuestionnairesAdnexal Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, endocrine system disorder, female reproductive system disorder, gonadal disorder, immune system disorder, kidney disorder, nephritis, ovarian disorder, primary ovarian failure, systemic lupus erythematosus, urinary system disorderRecruitingNot stated2026-09-28NCT05567198
Effects of Treatments on Atopic DermatitisCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypersensitivity, Immediate, Skin Diseases, Eczematous, Skin and Connective Tissue Diseases, atopic eczema, dermatitis, hereditary disease, hereditary skin disorder, immune system disorder, skin disorderRecruitingPhase 22026-09-28NCT01631617
Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)Skin and Connective Tissue Diseases, arteritis, autoimmune disease, autoimmune disorder of the nervous system, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system vasculitis, cerebrovascular disorder, immune system disorder, nervous system disorder, skin disorder, skin vascular disease, temporal arteritis, vascular disorder, vasculitisRecruitingNot stated2026-09-25NCT05865054
Natural History of Inflammatory Muscle DiseasesSkin and Connective Tissue Diseases, connective tissue disorder, dermatomyositis, muscle tissue disorder, musculoskeletal system disorder, myositis disease, nervous system disorder, neuromuscular disease, polymyositis, skin disorderRecruitingNot stated2026-09-24NCT05738824
Nutrition Optimization and Community Upliftment for Postpartum RecoveryBody Weight, Female Urogenital Diseases and Pregnancy Complications, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Pregnancy in Obesity, Signs and Symptoms, Urogenital Diseases, diabetes mellitus, endocrine system disorder, gestational diabetes, glucose metabolism disease, metabolic disease, nutritional disorder, obesity disorder, overnutrition, pregnancy disorderRecruitingNot applicable2026-09-22NCT06445530
Studies of Dermatologic Diseases Biospecimen Acquisition ProtocolDNA Virus Infections, Infections, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Tumor Virus Infections, adenocarcinoma, carcinoma, cutaneous neuroendocrine carcinoma, epithelial neoplasm, neoplasm, neuroendocrine carcinoma, neuroendocrine neoplasm, polyomavirus infectious disease, primitive neuroectodermal tumor, skin disorder, viral infectious diseaseRecruitingNot stated2026-09-22NCT02471352
The Role of Vitamin K on Knee Osteoarthritis OutcomesOsteo Arthritis KneeActive, not recruitingPhase 1 / Phase 22026-09-21NCT06385275
Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal InjuriesFractures, Open, Leg Injuries, bone fracture, injuryNot yet recruitingNot applicable2026-09-18NCT07828613
The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVDSkin and Connective Tissue Diseases, autoimmune disease, cardiovascular disorder, connective tissue disorder, immune system disorder, systemic lupus erythematosusRecruitingPhase 22026-09-18NCT05440422
Autologous Bone Marrow Aspirate Treatment for Early-Stage OsteonecrosisLegg-Calve-Perthes disease, Necrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, avascular necrosis of femoral head, primary, 1, bone disorder, familial avascular necrosis of femoral head, musculoskeletal system disorder, osteonecrosisRecruitingNot applicable2026-09-17NCT06123481
Natural History Study of Mitochondrial MyopathyFatigue, Muscle Weakness, Neurologic Manifestations, Neuromuscular Manifestations, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, metabolic disease, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular diseaseRecruitingNot stated2026-09-17NCT05250375
Algorithm-informed Decision-making to Advance Pain TreatmentChronic Low-back PainRecruitingNot applicable2026-09-15NCT07731750
ACL Reconstruction Rehabilitation With Exercise and Psychological SupportAnterior Cruciate Ligament Reconstruction RehabilitationRecruitingNot applicable2026-09-15NCT06991192
Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL ReconstructionAnterior Cruciate Ligament Injuries, Knee Injuries, Leg Injuries, injuryRecruitingNot applicable2026-09-15NCT06529692
The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) StudyFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, nephritis, systemic lupus erythematosus, urinary system disorderRecruitingPhase 22026-09-14NCT05538208