Alzheimer's Therapeutic Research Institute | ClinicalTrials HQ

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Trial	Conditions	Status	Phase	Updated	More info	NCT ID
The Progressive Supranuclear Palsy Clinical Trial Platform	Neurologic Manifestations, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, tauopathy	Recruiting	Phase 2	2026-10-09		NCT07173803
Alzheimer's Disease Neuroimaging Initiative 4	Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Enrolling by invitation	Not stated	2026-09-29		NCT05617014
Alzheimer's Tau Platform: Regimen A - AADvac1	Alzheimer disease, Frontotemporal Lobar Degeneration, Pick disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Enrolling by invitation	Phase 2	2026-09-08		NCT07167966
Alzheimer's Tau Platform: Master Protocol	Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Nerve Degeneration, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Recruiting	Phase 2	2026-09-08		NCT06957418
Alzheimer's Plasma Extension	Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Enrolling by invitation	Not stated	2026-08-18		NCT06416072
The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1	Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, proteostasis deficiencies, psychiatric disorder, tauopathy	Enrolling by invitation	Phase 2	2026-08-13		NCT07217665
The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31	Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, metabolic disease, movement disorder, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, proteostasis deficiencies, psychiatric disorder, tauopathy	Enrolling by invitation	Phase 2	2026-08-12		NCT07264283
Longitudinal Early-onset Alzheimer's Disease Study Protocol	Alzheimer Disease, Early Onset, Alzheimer disease, Cognition Disorders, Cognitive Dysfunction, Frontotemporal Lobar Degeneration, Mild Cognitive Impairment, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pick disease, Plaque, Amyloid, brain disorder, central nervous system disorder, cognitive disorder, dementia, frontotemporal dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Active, not recruiting	Not stated	2026-07-29		NCT03507257
Trial-Ready Cohort-Down Syndrome (TRC-DS)	Abnormalities, Multiple, Alzheimer disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Neurobehavioral Manifestations, Neurologic Manifestations, brain disorder, central nervous system disorder, chromosomal disorder, cognitive disorder, dementia, hereditary disease, intellectual disability, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Recruiting	Not stated	2026-05-18		NCT04165109
Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation	Abnormalities, Multiple, Alzheimer disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Plaque, Amyloid, brain disorder, central nervous system disorder, chromosomal disorder, cognitive disorder, dementia, hereditary disease, intellectual disability, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Not yet recruiting	Phase 4	2026-05-15		NCT06911944
Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study	Alzheimer Disease, Early Onset, Alzheimer disease, brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, neurodegenerative disease, psychiatric disorder, tauopathy	Recruiting	Not applicable	2026-05-06		NCT05573490
Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project	depressive disorder, major depressive disorder, mood disorder, psychiatric disorder	Recruiting	Not stated	2025-11-25		NCT02434393