Early phase 1 trials
Early phase 1 trials
Explore registered studies and their research locations.1,832 results · Page 1 of 74
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial | Cognition Disorders, Cognitive Dysfunction, Fatigue, Mental Fatigue, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, cognitive disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia, psychiatric disorder | Not yet recruiting | Early phase 1 | 2026-10-09 | NCT07757555 | |
| Ivabradine for Heart Rate Reduction During Exercise in Healthy Adults | Healthy Adult | Recruiting | Early phase 1 | 2026-10-09 | NCT07717710 | |
| Predictors & Mechanisms of Adolescent PTSD | Stress Disorders, Traumatic, acute stress disorder, post-traumatic stress disorder, psychiatric disorder | Not yet recruiting | Early phase 1 | 2026-10-09 | NCT07537764 | |
| Causal Mechanisms of Odor-Guided Behavior in Humans | Normal Physiology | Not yet recruiting | Early phase 1 | 2026-10-09 | NCT07099092 | |
| Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making | Normal Physiology | Recruiting | Early phase 1 | 2026-10-09 | NCT06561828 | |
| Reducing Fatigue With CoQ10 Supplementation in Patients With Crohn's Disease Study | Crohn disease, Digestive System Diseases, digestive system disorder, gastroenteritis, inflammatory bowel disease, intestinal disorder | Active, not recruiting | Early phase 1 | 2026-10-09 | NCT06419335 | |
| Simplifying Hepatitis C Pathways for People Who Inject Drugs in Armenia, Georgia, and Tanzania | Blood-Borne Infections, Digestive System Diseases, Flaviviridae infectious disease, Infections, RNA Virus Infections, hepatitis, hepatitis C virus infection, infectious disease, liver disorder, viral hepatitis, viral infectious disease | Recruiting | Early phase 1 | 2026-10-09 | NCT06159504 | |
| Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint Pain | Sacro-iliac Joint Pain | Recruiting | Early phase 1 | 2026-10-09 | NCT06081101 | |
| Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries. | Neurologic Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Postoperative Pain, Signs and Symptoms | Active, not recruiting | Early phase 1 | 2026-10-08 | NCT07866508 | |
| Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke Patients | Disease Attributes, Healthcare-Associated Pneumonia, Infections, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pneumonia, Ventilator-Associated, iatrogenic disease, lung disorder, nosocomial infection, pneumonia, respiratory system disorder, respiratory tract infectious disorder | Not yet recruiting | Early phase 1 | 2026-10-08 | NCT07865871 | |
| A Study of CA9-Targeted CAR Macrophage Therapy in Advanced Clear Cell Renal Cell Carcinoma | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, carcinoma, clear cell renal carcinoma, epithelial neoplasm, kidney cancer, kidney disorder, neoplasm, renal cell carcinoma, urinary system disorder | Not yet recruiting | Early phase 1 | 2026-10-08 | NCT07865832 | |
| Proof-of-Concept Clinical Pharmacology Trial for HIV Antigen Presentation Therapeutic Biologic Mix | AIDS, Blood-Borne Infections, Genital Diseases, HIV infectious disease, Infections, RNA Virus Infections, Slow Virus Diseases, Urogenital Diseases, immune system disorder, inborn error of immunity, infectious disease, lentivirus infection, sexually transmitted disease, uterine carcinosarcoma, viral infectious disease, viral sexually transmitted disease | Active, not recruiting | Early phase 1 | 2026-10-08 | NCT07182838 | |
| Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, brain disorder, central nervous system cancer, central nervous system disorder, cervix disorder, female reproductive system disorder, female reproductive system neoplasm, neoplasm, nervous system disorder, uterine disorder | Active, not recruiting | Early phase 1 | 2026-10-08 | NCT05047913 | |
| Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide | Chronic Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Hemic and Lymphatic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, X-linked disease, chronic granulomatous disease, graft versus host disease, hematologic disorder, hereditary disease, immune system disorder, inborn error of immunity, leukocyte disorder, phagocyte bactericidal dysfunction | Active, not recruiting | Early phase 1 | 2026-10-08 | NCT03910452 | |
| Study of GI001 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma and B-Cell Acute Lymphoblastic Leukemia | B-cell acute lymphoblastic leukemia, B-cell neoplasm, B-cell non-Hodgkin lymphoma, Burkitt lymphoma, DNA Virus Infections, Epstein-Barr virus infection, Hemic and Lymphatic Diseases, Herpesviridae infectious disease, Infections, Neoplasms by Histologic Type, Tumor Virus Infections, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, viral infectious disease | Recruiting | Early phase 1 | 2026-10-07 | NCT07862010 | |
| Feasibility Study Evaluating the Safety and Effectiveness of Magnetic Bead Tracking System When Used With a Bionic External Prosthesis | Transtibial Amputation; Transtibial Amputee | Active, not recruiting | Early phase 1 | 2026-10-07 | NCT07195461 | |
| Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine | depressive disorder, major depressive disorder, mood disorder, psychiatric disorder | Recruiting | Early phase 1 | 2026-10-07 | NCT06788249 | |
| DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer | Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinoma | Active, not recruiting | Early phase 1 | 2026-10-07 | NCT02744053 | |
| Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis | Chemically-Induced Disorders, cannabis dependence, psychiatric disorder, substance-related disorder | Not yet recruiting | Early phase 1 | 2026-10-06 | NCT07694466 | |
| SMART 2D: Study of Montelukast's Effects on Renal and Cardiovascular Health in Adolescents and Young Adults With Type 2 Diabetes | Inflammation, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, diabetes mellitus, endocrine system disorder, glucose metabolism disease, metabolic disease, type 2 diabetes mellitus | Recruiting | Early phase 1 | 2026-10-06 | NCT07409714 | |
| CBTi for the Treatment of Insomnia in Type 1 Diabetes | Dyssomnias, Nutritional and Metabolic Diseases, Sleep Disorders, Intrinsic, autoimmune disease, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, insomnia, metabolic disease, nervous system disorder, psychiatric disorder, sleep-wake disorder, type 1 diabetes mellitus | Recruiting | Early phase 1 | 2026-10-06 | NCT07091318 | |
| OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma | Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, endocrine system disorder, malignant endocrine neoplasm, neoplasm, pancreas disorder, pancreatic neoplasm | Recruiting | Early phase 1 | 2026-10-06 | NCT07089940 | |
| Efficacy and Safety of Sanggua Tablets in the Treatment of Patients With Impaired Glucose Tolerance and Mild Type 2 Diabetes | Nutritional and Metabolic Diseases, diabetes mellitus, endocrine system disorder, glucose intolerance, glucose metabolism disease, hyperglycemia, metabolic disease, type 2 diabetes mellitus | Recruiting | Early phase 1 | 2026-10-06 | NCT06964620 | |
| Study Brain Mechanisms of Frustration With Magnetoencephalography in Healthy Volunteers | Irritability | Recruiting | Early phase 1 | 2026-10-06 | NCT06484088 | |
| Testosterone and Neural Function in Men With Spinal Cord Injury | central nervous system disorder, injury, nervous system disorder, nervous system injury, spinal cord disorder, spinal cord injury | Recruiting | Early phase 1 | 2026-10-06 | NCT06130449 |