National Institutes of Health
National Institutes of Health
Bethesda, Maryland, United States10 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome | B-cell chronic lymphocytic leukemia, Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, B-Cell, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Richter transformation, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoproliferative syndrome, neoplasm | Active, not recruiting | Phase 1 / Phase 2 | 2026-10-06 | NCT04623541 | |
| SPEARHEAD-3 Pediatric Study | Neoplasms by Histologic Type, Neoplasms, Bone Tissue, Neoplasms, Connective and Soft Tissue, Neoplasms, Fibrous Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, connective tissue neoplasm, epithelial neoplasm, fibrosarcoma, neoplasm, nerve sheath neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, neurofibroma, neurofibrosarcoma, neuromuscular disease, osteosarcoma, peripheral nervous system disorder, peripheral nervous system neoplasm, primitive neuroectodermal tumor, sarcoma, synovial sarcoma | Recruiting | Phase 1 / Phase 2 | 2026-08-11 | NCT05642455 | |
| A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors | Abdominal Neoplasms, Biliary Tract Neoplasms, DNA Virus Infections, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Epstein-Barr virus infection, Esophageal Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Genomic Instability, Head and Neck Neoplasms, Herpesviridae infectious disease, Infections, Male Urogenital Diseases, Microsatellite Instability, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Otorhinolaryngologic Neoplasms, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pharyngeal Diseases, Skin and Connective Tissue Diseases, Stomatognathic Diseases, Thoracic Neoplasms, Tumor Virus Infections, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, adenocarcinoma, basal cell carcinoma, basal cell neoplasm, benign urinary system neoplasm, biliary tract disorder, bronchial neoplasm, bronchogenic carcinoma, carcinoma, cervix disorder, colonic disorder, colorectal cancer, colorectal neoplasm, cutaneous neuroendocrine carcinoma, digestive system disorder, digestive system neoplasm, endometrium neoplasm, epithelial neoplasm, esophageal disorder, female reproductive system disorder, female reproductive system neoplasm, gastric neoplasm, human papilloma virus infection, infectious disease, intestinal disorder, lung disorder, lung neoplasm, melanocytic neoplasm, melanoma, nasopharyngeal disorder, nasopharyngeal neoplasm, neoplasm, neuroendocrine carcinoma, neuroendocrine neoplasm, non-small cell lung carcinoma, otorhinolaryngologic disease, polyomavirus infectious disease, primitive neuroectodermal tumor, rectal disorder, respiratory system disorder, respiratory tract neoplasm, sexually transmitted disease, skin disorder, skin neoplasm, small cell lung carcinoma, stomach disorder, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder, uterine disorder, viral infectious disease, viral sexually transmitted disease, vulva cancer, vulvar disease | Recruiting | Phase 1 / Phase 2 | 2026-08-11 | NCT05592626 | |
| Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome | Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Phelan-McDermid syndrome, Signs and Symptoms, autism spectrum disorder, intellectual disability, nervous system disorder, neurodevelopmental disorder, pervasive developmental disorder, psychiatric disorder | Active, not recruiting | Not stated | 2026-08-06 | NCT02461420 | |
| Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation | Infusion Reactions | Recruiting | Phase 2 | 2026-04-13 | NCT01656603 | |
| The LD Lync Study - Natural History Study of Lipodystrophy Syndromes | Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, Skin Diseases, Metabolic, Skin and Connective Tissue Diseases, lipodystrophy, metabolic disease, skin disorder | Recruiting | Not stated | 2026-03-19 | NCT03087253 | |
| Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms | Choroid Plexus Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Teratoid Rhabdoid Tumor, Typical Teratoid Rhabdoid Tumor, anaplastic astrocytoma, anaplastic ependymoma, anaplastic meningioma, anaplastic oligodendroglioma, anaplastic pleomorphic xanthoastrocytoma, astrocytoma (excluding glioblastoma), brain disorder, central nervous system cancer, central nervous system disorder, cerebral ventricle cancer, diffuse astrocytoma, diffuse midline glioma, H3 K27M-mutant, ependymoma, epithelial neoplasm, glioblastoma, glioma, gliomatosis cerebri, gliosarcoma, medulloblastoma, meningioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, oligodendroglioma, pilocytic astrocytoma, pineal body neoplasm, primitive neuroectodermal tumor, tumor of meninges, vascular cancer | Recruiting | Phase 1 | 2025-12-18 | NCT04541082 | |
| Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals | In-hospital Mortality; Non-COVID Deaths; Surge | Active, not recruiting | Not stated | 2025-04-29 | NCT06651645 | |
| X-linked Moesin Associated Immunodeficiency | Infections, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autoimmune disease, disease, immune system disorder, inborn error of immunity | Recruiting | Not stated | 2025-04-25 | NCT06278337 | |
| Open-Label Extension Study of DCCR in Patients With Prader-Willi Syndrome | Abnormalities, Multiple, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Imprinting Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Prader-Willi syndrome, chromosomal disorder, hereditary disease, intellectual disability, nervous system disorder, nutritional disorder, obesity disorder, overnutrition | Active, not recruiting | Phase 3 | 2025-04-02 | NCT05701774 |