ClinicalTrials HQ

University of Iowa Hospitals & Clinics

University of Iowa Hospitals & Clinics

Iowa City, Iowa, United States

31 results ยท Page 1 of 2

Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
An Open-Label Study of CTI-1601 in Subjects With Friedreich's AtaxiaCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Friedreich ataxia, Nutritional and Metabolic Diseases, Spinocerebellar Degenerations, brain disorder, central nervous system disorder, cerebellar disorder, hereditary disease, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, spinal cord disorderRecruitingPhase 22026-10-09NCT06447025
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)Chemically-Induced Disorders, Digestive System Diseases, alcohol-induced disorders, alcohol-related disorders, alcoholic hepatitis, alcoholic liver disease, hepatitis, liver disorder, substance-related disorderRecruitingPhase 32026-10-06NCT07428538
Strategy for Improving Stroke Treatment Responsebrain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, ischemic stroke, nervous system disorder, stroke disorder, vascular disorderRecruitingPhase 22026-10-02NCT05948566
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasmRecruitingPhase 32026-09-29NCT06881784
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in AgingCognition Disorders, Cognitive Decline, Cognitive Dysfunction, Mild Cognitive Impairment, cognitive disorder, psychiatric disorderRecruitingNot applicable2026-09-28NCT03954899
Survivorship of Attune Primary Total Knee Prosthesisarthritic joint disease, arthropathy, musculoskeletal system disorder, osteoarthritis, rheumatic disorderActive, not recruitingNot applicable2026-09-28NCT01754363
A Study of the Safety and Effectiveness of the Mentor Larger Size MemoryGel Ultra High Profile Breast Implants in Subjects Who Are Undergoing Primary Breast Reconstruction or Revision ReconstructionBreast Reconstruction; Revision Breast ReconstructionActive, not recruitingNot applicable2026-09-25NCT02724371
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trialcardiovascular disorder, heart disorder, heart valve disorder, tricuspid valve disorder, tricuspid valve insufficiencyRecruitingNot applicable2026-09-14NCT04097145
Conditioning SCID Infants Diagnosed Earlysevere combined immunodeficiencyActive, not recruitingPhase 22026-08-28NCT03619551
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary CholangitisDigestive System Diseases, Fibrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Pruritus, Signs and Symptoms, Skin Manifestations, Skin and Connective Tissue Diseases, bile duct disorder, biliary tract disorder, cholangitis, cholestasis, cirrhosis of liver, intrahepatic cholestasis, liver disorder, primary biliary cholangitis, skin disorderActive, not recruitingPhase 22026-08-25NCT05050136
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid LeukemiaHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, acute leukemia, acute myeloid leukemia, acute myeloid leukemia with mutated NPM1, hematologic disorder, hematopoietic and lymphoid system neoplasm, leukemia, myeloid leukemia, neoplasmRecruitingPhase 12026-08-20NCT06001788
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield TrialsStroke, Acute, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, ischemic stroke, nervous system disorder, stroke disorder, vascular disorderRecruitingNot stated2026-08-20NCT05338697
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trialcardiovascular disorder, heart disorder, heart valve disorder, mitral valve insufficiencyActive, not recruitingNot applicable2026-07-08NCT03706833
Antibiotic Prophylaxis in High-Risk Arthroplasty PatientsBody Weight, Chronic Disease, Chronic Kidney Diseases, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Urogenital Diseases, autoimmune disease, chronic renal failure syndrome, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, inflammatory disease, kidney disorder, kidney failure, metabolic disease, methicillin-resistant staphylococcus aureus infectious disease, nutritional disorder, obesity disorder, overnutrition, urinary system disorderEnrolling by invitationPhase 42026-07-06NCT04297592
The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)Brain Injuries, Traumatic, Charcot-Marie-Tooth disease type 1F, Craniocerebral Trauma, brain disorder, brain injury, central nervous system disorder, injury, nervous system disorder, nervous system injuryRecruitingNot stated2026-06-22NCT04855396
Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon CancersDigestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, colonic disorder, colonic neoplasm, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, malignant colon neoplasm, neoplasmRecruitingPhase 22026-06-12NCT05239546
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failurecardiovascular disorder, heart disorder, heart failure, hypertensive disorder, lung disorder, pulmonary hypertension, respiratory system disorder, vascular disorderRecruitingNot applicable2026-06-10NCT06526195
KO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsDigestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, bronchial neoplasm, bronchogenic carcinoma, carcinoma, colonic disorder, colorectal neoplasm, digestive system disorder, digestive system neoplasm, epithelial neoplasm, intestinal disorder, kidney cancer, kidney disorder, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, rectal disorder, renal cell carcinoma, respiratory system disorder, respiratory tract neoplasm, urinary system disorderRecruitingPhase 12026-06-08NCT06026410
CREST-2 Long-term Observational Extension StudyArterial Occlusive Diseases, brain disorder, cardiovascular disorder, carotid artery disorder, carotid stenosis, central nervous system disorder, cerebrovascular disorder, nervous system disorder, vascular disorderActive, not recruitingNot stated2026-05-28NCT05465122
Palbociclib and Pembrolizumab in SarcomaNeoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, neoplasm, sarcomaRecruitingPhase 12026-05-22NCT06113809
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, neoplasm, neuroepithelial neoplasm, primitive neuroectodermal tumorRecruitingPhase 32026-04-16NCT05580562
A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical TherapyArthropathy of KneeRecruitingNot applicable2026-03-25NCT04924205
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AMLHemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, acute myeloid leukemia, acute myeloid leukemia with mutated NPM1, hematologic disorder, hematopoietic and lymphoid system neoplasm, leukemia, myeloid leukemia, myeloid sarcoma, neoplasm, sarcomaRecruitingPhase 12026-03-13NCT05735184
Long-Term Follow-up StudyB-cell neoplasm, B-cell non-Hodgkin lymphoma, Blood Protein Disorders, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, acute myeloid leukemia, cardiovascular disorder, hematologic disorder, hematopoietic and lymphoid system neoplasm, hemorrhagic disease, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, monoclonal gammopathy, myeloid leukemia, neoplasm, non-Hodgkin lymphoma, plasma cell neoplasm, vascular disorder, vascular hemostatic diseaseEnrolling by invitationNot stated2026-03-12NCT05332054
Seleno-L Methionine (SLM)-Axitinib-PembrolizumabClear-cell metastatic renal cell carcinoma, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, carcinoma, clear cell renal carcinoma, epithelial neoplasm, kidney cancer, kidney disorder, neoplasm, renal cell carcinoma, urinary system disorderActive, not recruitingPhase 1 / Phase 22025-12-10NCT05363631