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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)Geographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 2 / Phase 32026-09-30NCT06635148
ORACLE: A Long-term Follow-up Study to Evaluate the Safety of GT005 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration Treated in a Gyroscope-sponsored Antecedent StudyEye Diseases, Hereditary, Geographic Atrophy, Skin Abnormalities, Skin and Connective Tissue Diseases, connective tissue disorder, eye disorder, macular degeneration, primary anetoderma, retinal degeneration, retinal disorder, skin disorderEnrolling by invitationPhase 22026-09-28NCT05481827
Extension Study for the Port Delivery System With Ranibizumab (Portal)Neovascular Age-Related Macular DegenerationRecruitingPhase 32026-09-28NCT03683251
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure ParticipantsMacular Telangiectasia Type 2 (MacTel)RecruitingPhase 42026-09-25NCT06971939
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, autosomal recessive bestrophinopathy, eye disorder, hereditary disease, macular degeneration, retinal degeneration, retinal disorder, vitelliform macular dystrophy, vitelliform macular dystrophy 2RecruitingPhase 1 / Phase 22026-09-24NCT07185256
A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (GLOBALIGHT)Dry Age-related Macular DegenerationRecruitingNot stated2026-09-22NCT06351605
Hydrus® Microstent New Enrollment Post-Approval StudyGlaucoma, Primary Open Angle, eye disorder, glaucoma, ocular hypertension, open-angle glaucomaRecruitingNot applicable2026-09-22NCT04553523
ExCrossV Multi Site Trial for Vascularized High Risk KeratoplastyCorneal Transplant FailureRecruitingPhase 22026-09-21NCT06753916
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic AtrophyGeographic Atrophy, eye disorder, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 32026-09-18NCT06541704
A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)diabetic macular edemaActive, not recruitingPhase 32026-09-18NCT06491914
A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye ConditionsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Stargardt disease, eye disorder, hereditary disease, macular degeneration, retinal degeneration, retinal disorderRecruitingPhase 12026-09-16NCT07734064
NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular DegenerationEye Diseases, Hereditary, Metaplasia, Neovascularization, Pathologic, Pathologic Processes, Pathological Conditions, Signs and Symptoms, age-related macular degeneration, choroidal neovascularization, eye disorder, macular degeneration, optic choroid disorder, retinal degeneration, retinal disorder, uveal disorder, wet macular degenerationActive, not recruitingPhase 1 / Phase 22026-09-10NCT05984927
A Study to Learn How Stargardt-type Eye Conditions Progress in Children and AdultsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Eye Diseases, Hereditary, Stargardt disease, eye disorder, hereditary disease, macular degeneration, retinal degeneration, retinal disorderRecruitingNot stated2026-08-25NCT07425574
Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degenerationage-related macular degeneration, eye disorder, macular degeneration, retinal degeneration, retinal disorderActive, not recruitingPhase 1 / Phase 22026-07-27NCT02286089
A Prospective Longitudinal Analysis of Faricimab (Vabysmo 6mg) For Choroidal Neovascularization in Presumed Ocular Histoplasmosis SyndromePresumed Ocular HistoplasmosisRecruitingPhase 42026-07-10NCT07695298
A Phase 2 Open-label Study to Evaluate the Safety of Laruparetigene Zovaparvovec Administered Bilaterally in Male Participants With X-Linked Retinitis PigmentosaEye Diseases, Hereditary, eye disorder, retinal degeneration, retinal disorderActive, not recruitingPhase 22026-06-25NCT07174726
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degenerationeye disorder, macular degeneration, retinal degeneration, retinal disorder, wet macular degenerationRecruitingPhase 32026-04-16NCT07064759
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With XLRPEye Diseases, Hereditary, eye disorder, retinal degeneration, retinal disorderActive, not recruitingPhase 2 / Phase 32026-04-07NCT04850118
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular DegenerationNeovascular Age-related Macular DegenerationActive, not recruitingPhase 32025-06-17NCT06495918
A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)Eye Diseases, Hereditary, eye disorder, retinal degeneration, retinal disorderEnrolling by invitationPhase 22024-10-30NCT06275620
A Study Comparing Two Doses of AGTC-501 in Male Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (SKYLINE)Eye Diseases, Hereditary, eye disorder, retinal degeneration, retinal disorderActive, not recruitingPhase 22024-08-12NCT06333249
Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR MutationsEye Diseases, Hereditary, eye disorder, retinal degeneration, retinal disorderActive, not recruitingPhase 1 / Phase 22024-05-20NCT03316560