Duke University Health System
Duke University Health System
Durham, North Carolina, United States31 results ยท Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, Undiagnosed Diseases, hereditary disease | Recruiting | Not stated | 2026-10-07 | NCT02450851 | |
| A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis | Cholangitis, Sclerosing, Digestive System Diseases, bile duct disorder, biliary tract disorder, cholangitis, primary sclerosing cholangitis | Recruiting | Phase 3 | 2026-10-01 | NCT07387549 | |
| Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX) | CNS demyelinating autoimmune disease, Infections, Neoplasms by Site, Neuroinflammatory Diseases, Paraneoplastic Syndromes, Nervous System, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, central nervous system disorder, central nervous system infectious disorder, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, myelitis, neoplasm, nervous system disorder, neurodegenerative disease, optic nerve disorder, optic neuritis, paraneoplastic syndrome, spinal cord disorder | Recruiting | Phase 3 | 2026-09-24 | NCT07100990 | |
| A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease | Cognition Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Huntington disease, basal ganglia disorder, brain disorder, central nervous system disorder, choreatic disease, cognitive disorder, dementia, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, psychiatric disorder | Recruiting | Phase 3 | 2026-09-22 | NCT07326709 | |
| A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome | Epilepsies, Myoclonic, Epilepsy, Generalized, Epileptic Syndromes, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, nervous system disorder, visual epilepsy | Recruiting | Phase 3 | 2026-09-15 | NCT04462770 | |
| Hepatic Resection for Metastatic Pancreatic Cancer | Digestive System Diseases, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, endocrine system disorder, malignant endocrine neoplasm, neoplasm, pancreas disorder, pancreatic neoplasm | Active, not recruiting | Not stated | 2026-08-27 | NCT02892305 | |
| Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke | Hemianopsia, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Quadrantanopsia, Sensation Disorders, Signs and Symptoms, blindness (disorder), brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, eye disorder, nervous system disorder, stroke disorder, vascular disorder, vision disorder | Not yet recruiting | Not applicable | 2026-08-24 | NCT06875206 | |
| OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events | Infarction, Necrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, coronary artery disorder, heart disorder, ischemic disease, myocardial infarction, myocardial ischemia, vascular disorder | Recruiting | Phase 3 | 2026-08-21 | NCT07136012 | |
| Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) | Abnormalities, Multiple, Arrhythmias, Cardiac, COVID-19, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Coronaviridae Infections, Down syndrome, Dyssomnias, Edema, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Hemic and Lymphatic Diseases, Hemorrhage, Infant, Newborn, Diseases, Infant, Premature, Diseases, Infections, Inflammation, Kawasaki disease, Lung Injury, Menorrhagia, Menstruation Disturbances, Neurobehavioral Manifestations, Neurologic Manifestations, Nidovirales infectious disease, Nutritional and Metabolic Diseases, Orthocoronavirinae infectious disease, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, Signs and Symptoms, Skin and Connective Tissue Diseases, Sleep Disorders, Intrinsic, Suppuration, Urogenital Diseases, Uterine Hemorrhage, Ventilator-Induced Lung Injury, Water-Electrolyte Imbalance, adrenal gland disorder, adrenal gland hyperfunction, adrenocortical insufficiency, attention deficit hyperactivity disorder, inattentive type, blood coagulation disease, bronchopulmonary dysplasia, cardiovascular disorder, cellulitis, chromosomal disorder, coagulation protein disease, connective tissue disorder, endocrine system disorder, female reproductive system disorder, heart disorder, heart failure, hematologic disorder, hemophilia A, hemorrhagic disease, hereditary disease, hyperaldosteronism, hyperphosphatemia, hypertensive disorder, inherited blood coagulation disorder, insomnia, intellectual disability, lung disorder, lymphatic system disorder, metabolic disease, nervous system disorder, neurodevelopmental disorder, oppositional defiant disorder, pediatric multisystem inflammatory disease, COVID-19 related, phosphorus metabolism disease, pneumonia, potassium deficiency disease, primary aldosteronism, psychiatric disorder, pulmonary arterial hypertension, pulmonary hypertension, respiratory system disorder, respiratory tract infectious disorder, skin disorder, skin disorder caused by infection, skin infection, skin vascular disease, sleep-wake disorder, uterine disorder, vascular disorder, vascular hemostatic disease, vasculitis, viral infectious disease, viral pneumonia | Recruiting | Not stated | 2026-08-21 | NCT04278404 | |
| A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart failure, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-08-19 | NCT05489705 | |
| Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy | BRCA1 Mutation; BRCA2 Mutation | Recruiting | Not applicable | 2026-08-04 | NCT06972719 | |
| Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease | common variable immunodeficiency, immune system disorder, inborn error of immunity, interstitial lung disease, lung disorder, respiratory system disorder | Recruiting | Phase 2 | 2026-07-22 | NCT04925375 | |
| Ferritin and Iron Burden in SAH sIRB | brain disorder, central nervous system disorder, cognitive disorder, dementia, nervous system disorder, psychiatric disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-07-20 | NCT03754725 | |
| Risk Stratification in Children With Concussion | Brain Concussion, Brain Injuries, Traumatic, Concussion, Mild, Craniocerebral Trauma, Head Injuries, Closed, Wounds, Nonpenetrating, brain disorder, brain injury, central nervous system disorder, injury, nervous system disorder, nervous system injury | Recruiting | Not stated | 2026-07-08 | NCT05825027 | |
| A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS) | Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder | Active, not recruiting | Phase 2 | 2026-07-07 | NCT06643481 | |
| Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs | Drug Resistant Epilepsy, brain disorder, central nervous system disorder, epilepsy, nervous system disorder | Recruiting | Not applicable | 2026-06-05 | NCT06545643 | |
| 5-SENSE Score Validation Study | Drug Resistant Epilepsy, brain disorder, central nervous system disorder, epilepsy, nervous system disorder | Enrolling by invitation | Not stated | 2026-06-05 | NCT06138808 | |
| IL-17 Blockade to Decrease irAEs (REPLAY) | Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, melanocytic neoplasm, melanoma, metastatic melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasm | Recruiting | Phase 1 | 2026-06-04 | NCT07237594 | |
| REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 | COVID-19, Coronaviridae Infections, Critical Illness, Disease Attributes, Infections, Nidovirales infectious disease, Orthocoronavirinae infectious disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, lung disorder, pneumonia, respiratory system disorder, respiratory tract infectious disorder, viral infectious disease, viral pneumonia | Recruiting | Not applicable | 2026-05-28 | NCT05218083 | |
| MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases | Brain Metastases, Neoplasms by Site, brain disorder, central nervous system cancer, central nervous system disorder, neoplasm, nervous system disorder | Active, not recruiting | Not applicable | 2026-05-06 | NCT04246879 | |
| Development & Validation of Preoperative Objective Physiological Evaluation | Cardiorespiratory Fitness | Recruiting | Not applicable | 2026-04-27 | NCT05092126 | |
| Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2) | Hemorrhage, Intracranial Hemorrhages, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Subarachnoid Hemorrhage, Aneurysmal, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, nervous system disorder, subarachnoid hemorrhage, vascular disorder | Not yet recruiting | Phase 1 / Phase 2 | 2026-03-25 | NCT07493577 | |
| The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial | Intensive Care Unit (ICU); Non-cardiac Surgical | Recruiting | Not stated | 2026-02-27 | NCT06895590 | |
| IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma | Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Uveal Neoplasms, eye disorder, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, ocular cancer, primitive neuroectodermal tumor, skin disorder, skin neoplasm, uveal disorder, uveal melanoma | Active, not recruiting | Phase 2 / Phase 3 | 2026-02-17 | NCT05987332 | |
| Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery | Kyphosis, Spinal Curvatures, bone disorder, musculoskeletal system disorder, scoliosis, vertebral column disorder | Recruiting | Not stated | 2026-02-17 | NCT04885244 |