The Hospital for Sick Children
The Hospital for Sick Children
Toronto, Canada10 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation | Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Precursor Cell Lymphoblastic Leukemia-Lymphoma, acute biphenotypic leukemia, acute leukemia of ambiguous lineage, acute myeloid leukemia, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoproliferative syndrome, mixed phenotype acute leukemia, myeloid leukemia, neoplasm | Recruiting | Phase 1 / Phase 2 | 2026-10-09 | NCT04065399 | |
| An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Abnormalities, Digestive System Diseases, bile duct disorder, biliary atresia, biliary tract disorder | Active, not recruiting | Phase 3 | 2026-10-01 | NCT05426733 | |
| A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT | DNA Virus Infections, Infections, adenoviridae infectious disease, viral infectious disease | Recruiting | Phase 3 | 2026-08-10 | NCT07387367 | |
| Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation | Digestive System Diseases, Medulloblastoma, Childhood, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, atypical teratoid rhabdoid tumor, brain disorder, central nervous system cancer, central nervous system disorder, digestive system disorder, embryonal tumor with multilayered rosettes, ependymoblastoma, epithelial neoplasm, glioma, hypertrophic pyloric stenosis, medulloblastoma, medulloepithelioma, mixed neoplasm, neoplasm, nervous system disorder, neuroblastoma, neuroepithelial neoplasm, pineal body neoplasm, pineoblastoma, primitive neuroectodermal tumor, pyloric stenosis, rhabdoid tumor, stomach disorder | Recruiting | Early phase 1 | 2026-07-14 | NCT06942039 | |
| Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorder | Active, not recruiting | Phase 3 | 2026-06-05 | NCT06460506 | |
| Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorder | Active, not recruiting | Phase 3 | 2026-05-28 | NCT05422222 | |
| Microbiome and Malnutrition in Pregnancy | Disease Attributes, Female Urogenital Diseases and Pregnancy Complications, Infant Malnutrition, Infant Nutrition Disorders, Infections, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, infectious disease, nutritional deficiency disease, nutritional disorder, parasitic infectious disease, pregnancy disorder | Active, not recruiting | Not stated | 2026-04-28 | NCT04992104 | |
| Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer | Disease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, central nervous system cancer, childhood malignant neoplasm, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, nervous system disorder, refractory malignant neoplasm | Recruiting | Phase 1 / Phase 2 | 2026-01-28 | NCT06208657 | |
| Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children | Long Bone Fractures | Active, not recruiting | Not stated | 2025-09-12 | NCT04207892 | |
| Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block | Arrhythmias, Cardiac, Cardiac Conduction System Disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrioventricular dissociation, cardiovascular disorder, heart disorder | Recruiting | Not stated | 2024-05-22 | NCT04559425 |