Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
Indianapolis, Indiana, United States38 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors | Adnexal Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Urogenital Diseases, Urogenital Neoplasms, endocrine system disorder, endometrium neoplasm, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, male reproductive organ cancer, male reproductive system disorder, malignant endocrine neoplasm, neoplasm, ovarian cancer, ovarian disorder, ovarian germ cell tumor, testicular cancer, testicular disorder, testicular germ cell tumor, uterine disorder | Recruiting | Phase 1 | 2026-10-09 | NCT06276491 | |
| Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer | Anal Cancer, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, anus disorder, anus neoplasm, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, rectal disorder, rectal neoplasm | Recruiting | Phase 2 | 2026-10-07 | NCT06493019 | |
| A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma | B-cell neoplasm, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, diffuse large B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm | Recruiting | Phase 3 | 2026-10-07 | NCT06091865 | |
| ASCVD Management Using CCTA in Prostate Cancer Patients on ADT | Arterial Occlusive Diseases, Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, arteriosclerosis disorder, cardiovascular disorder, coronary artery disorder, heart disorder, male reproductive organ cancer, male reproductive system disorder, myocardial ischemia, neoplasm, prostate cancer, prostate disorder, vascular disorder | Recruiting | Not applicable | 2026-10-05 | NCT05879913 | |
| Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, Uterine Cervical Neoplasms, cervix disorder, female reproductive system disorder, female reproductive system neoplasm, neoplasm, uterine disorder | Recruiting | Phase 4 | 2026-09-25 | NCT06952660 | |
| Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, carcinoma, clear cell renal carcinoma, epithelial neoplasm, kidney cancer, kidney disorder, neoplasm, renal cell carcinoma, urinary system disorder | Recruiting | Phase 2 | 2026-09-22 | NCT06863311 | |
| Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Pelvic Pain, Sexual Dysfunctions, Psychological, Signs and Symptoms, Urogenital Diseases, female reproductive system disorder, injury, male reproductive system disorder, physiological sexual disorder, psychiatric disorder, psychologic dyspareunia, radiation injury | Recruiting | Not applicable | 2026-09-18 | NCT06059586 | |
| Pilot Study of Hydroxychloroquine for the Treatment of AIMSS | Arthralgia, Neoplasms by Site, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Skin and Connective Tissue Diseases, arthropathy, breast cancer, breast disorder, breast neoplasm, musculoskeletal system disorder, neoplasm, skin disorder | Not yet recruiting | Phase 2 | 2026-09-17 | NCT07825454 | |
| Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC) | Cardiotoxicity, Chemically-Induced Disorders, Drug-Related Side Effects and Adverse Reactions, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, cardiovascular disorder, heart disorder, injury, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, radiation injury, respiratory system disorder, respiratory tract neoplasm | Recruiting | Phase 2 | 2026-09-15 | NCT07761910 | |
| Toci +/- SOC Chemo for Metastatic Triple Negative and ER-positive, HER2-negative Breast Cancers | Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinoma | Recruiting | Phase 2 | 2026-09-03 | NCT05846789 | |
| Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer | Extensive Stage Small Cell Lung Cancer | Active, not recruiting | Phase 2 | 2026-09-03 | NCT04699838 | |
| ATEMPT 2.0: Adjuvant T-DM1 vs TH | Neoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorder | Recruiting | Phase 2 | 2026-08-19 | NCT04893109 | |
| A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer | Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, respiratory system disorder, respiratory tract neoplasm, small cell lung carcinoma | Recruiting | Phase 2 | 2026-08-17 | NCT06095505 | |
| Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC) | Biliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, adenocarcinoma, bile duct cancer, bile duct disorder, bile duct neoplasm, biliary tract disorder, carcinoma, cholangiocarcinoma, epithelial neoplasm, neoplasm | Active, not recruiting | Phase 2 | 2026-08-17 | NCT06048133 | |
| ctHPVDNA in HPV Positive Squamous Cell Carcinoma of the Oropharynx | Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Otorhinolaryngologic Neoplasms, Pharyngeal Diseases, Stomatognathic Diseases, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, neoplasm, oropharynx squamous cell carcinoma, otorhinolaryngologic disease, squamous cell carcinoma | Recruiting | Not applicable | 2026-08-11 | NCT06915038 | |
| CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer | Head and Neck Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, lung disorder, lung neoplasm, neoplasm, non-small cell lung carcinoma, respiratory system disorder, respiratory tract neoplasm, squamous cell carcinoma | Active, not recruiting | Phase 1 / Phase 2 | 2026-08-10 | NCT02955290 | |
| Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer | Muscle Invasive Bladder Urothelial Carcinoma | Recruiting | Phase 2 | 2026-08-05 | NCT06809140 | |
| Letrozole in Uterine Leiomyosarcoma | leiomyosarcoma of the corpus uteri | Recruiting | Phase 2 | 2026-07-30 | NCT05649956 | |
| Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26) | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, endometrium neoplasm, female reproductive system disorder, female reproductive system neoplasm, neoplasm, uterine disorder | Active, not recruiting | Phase 3 | 2026-07-29 | NCT06486441 | |
| Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study | Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genitourinary Cancer, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, Urogenital Diseases, Urogenital Neoplasms, digestive system disorder, digestive system neoplasm, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, sarcoma, skin disorder, skin neoplasm, thoracic cancer | Not yet recruiting | Early phase 1 | 2026-07-15 | NCT07389525 | |
| ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) | cancer, neoplasm | Not yet recruiting | Not stated | 2026-07-15 | NCT06900296 | |
| Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer | Neoplasms by Site, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, lung disorder, lung neoplasm, neoplasm, respiratory system disorder, respiratory tract neoplasm, small cell lung carcinoma | Recruiting | Not stated | 2026-07-14 | NCT05889546 | |
| Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma | B-cell neoplasm, Disease Attributes, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, diffuse large B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, refractory malignant neoplasm | Recruiting | Phase 2 | 2026-07-10 | NCT05852717 | |
| Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases | Neoplasms by Site, Skin and Connective Tissue Diseases, brain disorder, breast cancer, breast disorder, breast neoplasm, central nervous system cancer, central nervous system disorder, neoplasm, nervous system disorder, skin disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-07-10 | NCT04711824 | |
| CD4CAR for CD4+ Leukemia and Lymphoma | Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, T-cell leukemia, T-cell non-Hodgkin lymphoma, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoma, lymphoproliferative syndrome, neoplasm | Recruiting | Phase 1 | 2026-06-24 | NCT03829540 |