University Hospital - London Health Sciences Centre | ClinicalTrials HQ

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Trial	Conditions	Status	Phase	Updated	More info	NCT ID
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity	CNS demyelinating autoimmune disease, Muscle Hypertonia, Muscle Spasticity, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autoimmune disease, autoimmune disorder of the nervous system, demyelinating disease, immune system disorder, multiple sclerosis, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder	Recruiting	Phase 2	2026-10-01		NCT06782490
The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal Transplantation	Delayed Graft Function, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, cardiovascular disorder, ischemia reperfusion injury, vascular disorder	Recruiting	Not applicable	2026-09-18		NCT07726134
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)	Nutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorder	Recruiting	Phase 1 / Phase 2	2026-09-11		NCT06351592
An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)	Nutritional and Metabolic Diseases, amyloidosis, metabolic disease, proteostasis deficiencies	Enrolling by invitation	Phase 3	2026-04-17		NCT05667493