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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaBacterial Infections and Mycoses, Infections, Skin and Connective Tissue Diseases, Suppuration, bacterial infectious disease, hidradenitis, hidradenitis suppurativa, skin disease caused by bacterial infection, skin disorder, skin disorder caused by infection, sweat gland disorderRecruitingPhase 22026-10-09NCT07213973
HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLPCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, erythropoietic protoporphyria, hepatic porphyria, hereditary disease, hereditary skin disorder, liver disorder, metabolic disease, porphyria, skin disorderEnrolling by invitationPhase 2 / Phase 32026-10-09NCT05883748
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination TherapyCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorderActive, not recruitingPhase 32026-10-09NCT05444257
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut SyndromeCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Epileptic Syndromes, Lennox-Gastaut syndrome, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, hereditary disease, nervous system disorder, visual epilepsyRecruitingPhase 32026-10-09NCT05066217
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases NetworkCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rare Diseases, Undiagnosed Diseases, hereditary diseaseRecruitingNot stated2026-10-07NCT02450851
A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophyautonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathyActive, not recruitingPhase 22026-10-06NCT05923866
Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated CardiomyopathyNon-ischemic Dilated CardiomyopathyActive, not recruitingPhase 22026-09-29NCT04476901
A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathymultifocal motor neuropathyActive, not recruitingPhase 32026-09-22NCT06742190
Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R RecipientsFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Urogenital Diseases, kidney disorder, urinary system disorderRecruitingPhase 32026-09-21NCT06798909
A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1Disease Attributes, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, carcinoma, epithelial neoplasm, head and neck squamous cell carcinoma, neoplasm, squamous cell carcinomaActive, not recruitingPhase 2 / Phase 32026-09-21NCT04534205
A Comparative Effectiveness Study of Positive Airway Pressure (PAP) Therapy, Dental Device, and Atomoxetine-Oxybutynin for Treatment of Obstructive Sleep Apnea in AdultsApnea, Dyssomnias, Respiration Disorders, Sleep Disorders, Intrinsic, nervous system disorder, obstructive sleep apnea syndrome, respiratory system disorder, sleep apnea syndrome, sleep-wake disorderRecruitingPhase 42026-09-11NCT07679282
Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 TrialCognition Disorders, Cognitive Dysfunction, cognitive disorder, psychiatric disorderRecruitingPhase 22026-07-28NCT06601933
A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's DisorderCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Tourette syndrome, basal ganglia disorder, brain disorder, central nervous system disorder, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, neurodevelopmental disorder, psychiatric disorder, tic disorderActive, not recruitingPhase 32026-07-22NCT06021522
A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus NephritisFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Skin and Connective Tissue Diseases, Urogenital Diseases, autoimmune disease, connective tissue disorder, glomerulonephritis, immune system disorder, kidney disorder, lupus nephritis, nephritis, systemic lupus erythematosus, urinary system disorderActive, not recruitingPhase 32026-07-21NCT04221477
Nephrotic Syndrome Study NetworkFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Urogenital Diseases, autoimmune disease, focal segmental glomerulosclerosis, glomerulonephritis, immune system disorder, kidney disorder, macular corneal dystrophy, membranous glomerulonephritis, minimal change disease, nephritis, nephrosis, nephrotic syndrome, urinary system disorderRecruitingNot stated2026-06-10NCT01209000
Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A PatientsCongenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, blood coagulation disease, coagulation protein disease, hematologic disorder, hemophilia A, hemorrhagic disease, hereditary disease, inherited blood coagulation disorderRecruitingNot stated2026-06-02NCT03695978
A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic LymphomaB-cell neoplasm, Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, diffuse large B-cell lymphoma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, plasmablastic lymphomaRecruitingEarly phase 12026-06-01NCT04139304
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)prurigo nodularisActive, not recruitingPhase 32026-05-28NCT06516952
Chronic Subdural Hematoma Treatment With Embolization Versus Surgery StudyChronic Disease, Craniocerebral Trauma, Disease Attributes, Hematoma, Hematoma, Subdural, Hematoma, Subdural, Chronic, Hemorrhage, Intracranial Hemorrhage, Traumatic, Intracranial Hemorrhages, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, injury, nervous system disorder, nervous system injury, vascular disorderRecruitingNot applicable2026-05-22NCT06347796
Single or Repeated Intravenous Administration of umbiliCAl Cord Mesenchymal sTrOmal Cells in Ischemic Cardiomyopathycardiovascular disorder, heart disorder, myocardial ischemia, vascular disorderRecruitingPhase 22026-05-13NCT06145035
Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)Digestive System Diseases, Fibrosis, Pathologic Processes, Pathological Conditions, Signs and Symptoms, bile duct disorder, biliary tract disorder, cholestasis, cirrhosis of liver, intrahepatic cholestasis, liver disorder, primary biliary cholangitisActive, not recruitingPhase 32026-05-04NCT03301506
Spastic Paraplegia - Centers of Excellence Research NetworkCongenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Spastic Paraplegia Type 4, central nervous system malformation, hereditary disease, hereditary motor and sensory neuropathy, hereditary spastic paraplegia, hereditary spastic paraplegia 4, hereditary spastic paraplegia 5A, inherited neurodegenerative disorder, lateral sclerosis, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, polyneuropathyRecruitingNot stated2026-03-18NCT06553976
Trial of Ixazomib for Kaposi SarcomaDNA Virus Infections, Herpesviridae infectious disease, Infections, Kaposi's sarcoma, Neoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, neoplasm, sarcoma, vascular cancer, viral infectious diseaseRecruitingPhase 22026-02-27NCT04305691
Intermuscular Coherence as a Biomarker for ALSNutritional and Metabolic Diseases, TDP-43 proteinopathy, amyotrophic lateral sclerosis, central nervous system disorder, metabolic disease, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proteostasis deficiencies, spinal cord disorderRecruitingNot stated2026-02-09NCT05104710
A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus ErythematosusSkin and Connective Tissue Diseases, autoimmune disease, connective tissue disorder, immune system disorder, systemic lupus erythematosusActive, not recruitingPhase 32026-01-29NCT04961567