Cleveland Clinic
Cleveland Clinic
Cleveland, Ohio, United States21 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. | cardiovascular disorder, heart disorder, heart failure, heart valve disorder, tricuspid valve disorder, tricuspid valve insufficiency | Not yet recruiting | Not applicable | 2026-10-09 | NCT06458907 | |
| Safety and Efficacy Study of Safusidenib in Participants With IDH1-Mutant Glioma Who Discontinued Vorasidenib Treatment Due to Progressive Disease | Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, epithelial neoplasm, glioma, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumor | Not yet recruiting | Phase 2 | 2026-09-22 | NCT07703436 | |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7497372 in Participants With Diabetic Macular Edema (DME) | diabetic macular edema | Active, not recruiting | Phase 1 | 2026-09-02 | NCT06847854 | |
| TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I) | cardiovascular disorder, heart disorder, heart failure, heart valve disorder, tricuspid valve disorder, tricuspid valve insufficiency | Active, not recruiting | Not applicable | 2026-08-28 | NCT06137807 | |
| SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance) | Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, astrocytoma (excluding glioblastoma), astrocytoma, IDH-mutant, grade 2, astrocytoma, IDH-mutant, grade 3, astrocytoma, IDH-mutant, grade 4, epithelial neoplasm, follicular lymphoma, glioblastoma, glioma, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm, neuroepithelial neoplasm, oligodendroglioma, primitive neuroectodermal tumor | Recruiting | Phase 3 | 2026-08-28 | NCT05303519 | |
| Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML | Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, acute myeloid leukemia, hematologic disorder, leukemia, myelodysplastic syndrome, myeloid leukemia, neoplasm | Recruiting | Phase 1 | 2026-08-25 | NCT06533761 | |
| A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer | Urothelial Cancer | Active, not recruiting | Phase 2 | 2026-07-28 | NCT05645692 | |
| Signatera Assessment in Early-Stage Endometrial Cancer | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, endometrium neoplasm, female reproductive system disorder, female reproductive system neoplasm, neoplasm, uterine disorder | Not yet recruiting | Not applicable | 2026-06-17 | NCT07339384 | |
| Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease | Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorder | Recruiting | Phase 2 | 2026-06-01 | NCT06875128 | |
| APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) | Chronic Disease, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, chronic renal failure syndrome, kidney disorder, kidney failure, urinary system disorder | Active, not recruiting | Not stated | 2026-05-26 | NCT03615235 | |
| I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer | Disease Attributes, Disease Progression, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Pathologic Complete Response, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, angiosarcoma, breast cancer, breast disorder, breast neoplasm, neoplasm, sarcoma, skin disorder, triple-negative breast carcinoma, vascular cancer | Recruiting | Phase 2 | 2026-05-06 | NCT01042379 | |
| A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis | Hemic and Lymphatic Diseases, Hypertrophy, Myeloproliferative Disorders, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Splenomegaly, anemia, blood platelet disease, bone marrow disorder, hematologic disorder, hemorrhagic disease, primary myelofibrosis | Active, not recruiting | Phase 3 | 2026-04-30 | NCT03165734 | |
| Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study) | primary central nervous system lymphoma | Active, not recruiting | Phase 2 | 2026-03-30 | NCT04947319 | |
| Developing MRI Technologies for Atrial Fibrillation | Arrhythmias, Cardiac, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, cardiovascular disorder, heart disorder | Enrolling by invitation | Not stated | 2026-03-23 | NCT07083115 | |
| A Prospective Comparative Study of Outcomes With Proton and Photon Radiation in Prostate Cancer | Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate cancer, prostate disorder | Active, not recruiting | Not applicable | 2026-03-09 | NCT03561220 | |
| REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients | cardiovascular disorder, heart disorder, pericarditis | Active, not recruiting | Not stated | 2026-02-17 | NCT04687358 | |
| Evolutionary Therapy for Rhabdomyosarcoma | Myosarcoma, Neoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, myomatous neoplasm, neoplasm, rhabdomyosarcoma, sarcoma | Active, not recruiting | Phase 2 | 2025-11-26 | NCT04388839 | |
| A Comparison of TULSA Procedure vs. Radical Prostatectomy in Participants With Localized Prostate Cancer | Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, male reproductive organ cancer, male reproductive system disorder, neoplasm, prostate adenocarcinoma, prostate cancer, prostate disorder | Active, not recruiting | Not applicable | 2025-08-17 | NCT05027477 | |
| A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy | Adnexal Diseases, Carcinoma, Ovarian Epithelial, Disease Attributes, Disease Progression, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Complete Response, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, Urogenital Neoplasms, carcinoma, endocrine system disorder, epithelial neoplasm, fallopian tube cancer, fallopian tube disorder, fallopian tube neoplasm, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, malignant endocrine neoplasm, neoplasm, ovarian cancer, ovarian disorder | Active, not recruiting | Phase 3 | 2025-06-24 | NCT03522246 | |
| AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM | cardiovascular disorder, heart disorder, heart failure | Recruiting | Not stated | 2025-03-26 | NCT06378632 | |
| APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study | Neurologic Manifestations, Paralysis, Unilateral, Vocal Cord, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Vocal Cord Paralysis, cranial nerve neuropathy, laryngeal disorder, nervous system disorder, otorhinolaryngologic disease, palsy, respiratory system disorder, vagus nerve disorder | Recruiting | Not applicable | 2025-02-06 | NCT05119842 |