Craniofacial Abnormalities
Craniofacial Abnormalities
Explore linked clinical trials. Standard reference: MESH:M0028956146 results · Page 1 of 6
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Clinical Genetics Branch Eligibility Screening Survey | Abnormalities, Multiple, Bone Marrow Failure Disorders, Congenital Abnormalities, Congenital Bone Marrow Failure Syndromes, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Costello syndrome, Craniofacial Abnormalities, DNA repair disease, Fanconi anemia, Hemic and Lymphatic Diseases, Infant, Newborn, Diseases, Legius syndrome, Li-Fraumeni syndrome, Musculoskeletal Abnormalities, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, Thoracic Neoplasms, anemia, aplastic anemia, bone marrow disorder, cardiofaciocutaneous syndrome, chordoma, hematologic disorder, hereditary disease, hereditary neoplastic syndrome, inherited aplastic anemia, lung neoplasm, melanocytic neoplasm, melanoma, metabolic disease, mixed neoplasm, musculoskeletal system disorder, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, pulmonary blastoma, respiratory tract neoplasm, skin disorder, skin neoplasm, susceptibility to familial cutaneous melanoma | Not yet recruiting | Not stated | 2026-10-09 | NCT07005297 | |
| French Registry of Children Treated With Norditropin® for Short Stature Associated With Noonan Syndrome | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Noonan syndrome, Skin and Connective Tissue Diseases, cardiovascular disorder, congenital heart disease, connective tissue disorder, heart disorder, musculoskeletal system disorder | Enrolling by invitation | Not stated | 2026-10-08 | NCT05308927 | |
| Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies | Abnormalities, Multiple, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Costello syndrome, Craniofacial Abnormalities, Legius syndrome, Musculoskeletal Abnormalities, Noonan syndrome, RASopathy, Skin and Connective Tissue Diseases, capillary malformation-arteriovenous malformation syndrome, cardiofaciocutaneous syndrome, cardiovascular disorder, congenital heart disease, connective tissue disorder, heart disorder, hereditary disease, musculoskeletal system disorder | Recruiting | Not stated | 2026-10-02 | NCT04888936 | |
| Natural History and Genetics of Food Allergy and Related Conditions | Abnormalities, Multiple, Aneurysm, Bone Diseases, Developmental, Camurati-Engelmann disease, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, Loeys-Dietz syndrome, Musculoskeletal Abnormalities, Skin Diseases, Eczematous, Skin and Connective Tissue Diseases, aortic aneurysm, aortic disorder, atopic eczema, bone disorder, cardiovascular disorder, dermatitis, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, food allergy, gastroenteritis, hematologic disorder, hereditary disease, hereditary skin disorder, immune system disorder, leukocyte disorder, musculoskeletal system disorder, osteochondrodysplasia, skin disorder, vascular disorder | Recruiting | Not stated | 2026-10-02 | NCT02504853 | |
| Natural History of Craniofacial Anomalies and Developmental Growth Variants | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dentofacial Deformities, Female Urogenital Diseases and Pregnancy Complications, Fetal Diseases, Jaw Abnormalities, Jaw Diseases, Mandibular Diseases, Maxillofacial Abnormalities, Musculoskeletal Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Prognathism, Retrognathia, Retrognathism, Stomatognathic Diseases, Stomatognathic System Abnormalities, Urogenital Diseases, fetal growth restriction, hereditary endocrine growth disease, musculoskeletal system disorder, pregnancy disorder | Recruiting | Not stated | 2026-10-01 | NCT02639312 | |
| Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders | Bone Diseases, Developmental, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dwarfism, Failure to Thrive, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Musculoskeletal Abnormalities, Noonan syndrome, Pathological Conditions, Signs and Symptoms, Sex Chromosome Disorders, Signs and Symptoms, Skin and Connective Tissue Diseases, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, bone disorder, cardiovascular disorder, chromosomal disorder, congenital heart disease, connective tissue disorder, disorder of sexual differentiation, endocrine system disorder, gonadal disorder, gonadal dysgenesis, heart disorder, hereditary disease, musculoskeletal system disorder, sex chromosome disorder of sex development | Recruiting | Phase 3 | 2026-09-30 | NCT07221851 | |
| Treatment for "Asymmetric Crying Facies" | Bell's palsy, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Crouzon syndrome, DNA Virus Infections, Herpesviridae infectious disease, Infections, Musculoskeletal Abnormalities, Stomatognathic Diseases, bone disorder, cranial nerve neuropathy, craniofacial microsomia, dysostosis, facial nerve disorder, mandibulofacial dysostosis, mouth disorder, musculoskeletal system disorder, nervous system disorder, viral infectious disease | Recruiting | Not applicable | 2026-09-28 | NCT07802639 | |
| Comparing 3D-Printed and Milled Titanium Plates in Jaw Surgery (Le Fort I): Accuracy and Operative Time | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dentofacial Deformities, Malocclusion, Malocclusion, Angle Class II, Maxillofacial Abnormalities, Musculoskeletal Abnormalities, Stomatognathic Diseases, Stomatognathic System Abnormalities, autosomal dominant prognathism, musculoskeletal system disorder, tooth disorder | Recruiting | Not applicable | 2026-09-25 | NCT07841067 | |
| Furlow With Buccinator and Fistula Formation | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Fistula, Jaw Abnormalities, Jaw Diseases, Maxillofacial Abnormalities, Mouth Abnormalities, Musculoskeletal Abnormalities, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Stomatognathic Diseases, Stomatognathic System Abnormalities, cleft palate, mouth disorder, musculoskeletal system disorder | Not yet recruiting | Not applicable | 2026-09-25 | NCT07840911 | |
| Frontal Reconstruction Without Orbital Advancement for Moderate Metopic Craniosynostosis | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Metopic Synostosis, Musculoskeletal Abnormalities, Trigonocephaly, Nonsyndromic, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Not yet recruiting | Not applicable | 2026-09-23 | NCT07837453 | |
| A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment | Bone Diseases, Developmental, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dwarfism, Musculoskeletal Abnormalities, Noonan syndrome, Skin and Connective Tissue Diseases, bone disorder, cardiovascular disorder, congenital heart disease, connective tissue disorder, endocrine system disorder, heart disorder, hereditary disease, musculoskeletal system disorder | Active, not recruiting | Phase 2 | 2026-09-23 | NCT06668805 | |
| Effects of Tummy Time Associated With Therapeutic Positioning in Premature Newborns With Cranial Asymmetry | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases and Pregnancy Complications, Musculoskeletal Abnormalities, Obstetric Labor Complications, Obstetric Labor, Premature, Plagiocephaly, Plagiocephaly, Nonsynostotic, Premature Birth, Urogenital Diseases, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, pregnancy disorder, synostosis | Not yet recruiting | Not applicable | 2026-09-18 | NCT07758426 | |
| Clinical Trial of a MEK Inhibitor for RASopathy-Associated Severe Infantile Hypertrophic Cardiomyopathy: Baby MERIT | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Musculoskeletal Abnormalities, Noonan syndrome, Skin and Connective Tissue Diseases, cardiovascular disorder, congenital heart disease, connective tissue disorder, heart disorder, heart failure, musculoskeletal system disorder | Not yet recruiting | Phase 3 | 2026-09-14 | NCT07817186 | |
| Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and Costs | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Metopic Synostosis, Musculoskeletal Abnormalities, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, synostosis | Recruiting | Not stated | 2026-09-11 | NCT06069479 | |
| Nebulized Bupivacaine Analgesia for Cleft Palate Repair | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Jaw Abnormalities, Jaw Diseases, Maxillofacial Abnormalities, Mouth Abnormalities, Musculoskeletal Abnormalities, Stomatognathic Diseases, Stomatognathic System Abnormalities, cleft palate, mouth disorder, musculoskeletal system disorder | Recruiting | Phase 3 | 2026-09-09 | NCT04928352 | |
| ASO Treatment for Syndromic Craniosynostoses | Apert syndrome, Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Crouzon syndrome, Limb Deformities, Congenital, Muenke syndrome, Musculoskeletal Abnormalities, Pfeiffer syndrome, Saethre-Chotzen syndrome, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, syndactyly, synostosis | Recruiting | Not stated | 2026-09-08 | NCT07535372 | |
| Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dentofacial Deformities, Maxillofacial Abnormalities, Musculoskeletal Abnormalities, Stomatognathic Diseases, Stomatognathic System Abnormalities, musculoskeletal system disorder | Recruiting | Not applicable | 2026-09-08 | NCT06494709 | |
| Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Jaw Abnormalities, Jaw Diseases, Mandibular Diseases, Maxillofacial Abnormalities, Musculoskeletal Abnormalities, Retrognathia, Stomatognathic Diseases, Stomatognathic System Abnormalities, bone disorder, bone resorption disease, musculoskeletal system disorder | Recruiting | Not applicable | 2026-09-01 | NCT07619846 | |
| PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cowden disease, Craniofacial Abnormalities, Malformations of Cortical Development, Group I, Musculoskeletal Abnormalities, Neoplasms, Multiple Primary, PTEN hamartoma tumor syndrome, autism, autism spectrum disorder, central nervous system malformation, cerebral cortical dysplasia, hamartoma, hereditary disease, hereditary neoplastic syndrome, macrocephaly-autism syndrome, megalencephaly, musculoskeletal system disorder, neoplasm, nervous system disorder, neurodevelopmental disorder, pervasive developmental disorder, psychiatric disorder | Recruiting | Not stated | 2026-08-31 | NCT06462430 | |
| Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation | Bone Diseases, Developmental, Brachycephaly, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Dyskinesias, Musculoskeletal Abnormalities, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Plagiocephaly, Plagiocephaly, Nonsynostotic, Signs and Symptoms, bone disorder, craniosynostosis, dysostosis, dystonic disorder, inherited torticollis, musculoskeletal system disorder, synostosis | Recruiting | Not applicable | 2026-08-31 | NCT05917678 | |
| A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer | Bone Diseases, Developmental, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Limb Deformities, Congenital, Male Urogenital Diseases, Musculoskeletal Abnormalities, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, benign urinary system neoplasm, bone disorder, craniosynostosis, dysostosis, musculoskeletal system disorder, neoplasm, syndactyly, synostosis, urinary bladder disorder, urinary bladder neoplasm, urinary system disorder | Active, not recruiting | Phase 1 | 2026-08-28 | NCT05567185 | |
| Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial | Abnormalities, Multiple, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Costello syndrome, Craniofacial Abnormalities, Legius syndrome, Musculoskeletal Abnormalities, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Noonan syndrome, Skin and Connective Tissue Diseases, cardiofaciocutaneous syndrome, cardiovascular disorder, congenital heart disease, connective tissue disorder, heart disorder, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, musculoskeletal system disorder, neoplasm, nerve sheath neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neurofibroma, neurofibromatosis, neurofibromatosis type 1, neuromuscular disease, peripheral nervous system disorder | Recruiting | Not applicable | 2026-08-24 | NCT05361811 | |
| A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9 | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Musculoskeletal Abnormalities, Noonan syndrome, Sex Chromosome Disorders, Skin and Connective Tissue Diseases, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, cardiovascular disorder, chromosomal disorder, congenital heart disease, connective tissue disorder, disorder of sexual differentiation, endocrine system disorder, gonadal disorder, gonadal dysgenesis, heart disorder, hereditary disease, musculoskeletal system disorder, sex chromosome disorder of sex development | Active, not recruiting | Phase 3 | 2026-08-13 | NCT05723835 | |
| Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME) | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Focal Cortical Dysplasia, Malformations of Cortical Development, Group I, Musculoskeletal Abnormalities, Neoplasms, Multiple Primary, central nervous system malformation, cerebral cortical dysplasia, hamartoma, hemimegalencephaly, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, megalencephaly, musculoskeletal system disorder, neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, tuberous sclerosis | Recruiting | Phase 1 / Phase 2 | 2026-08-10 | NCT07287202 | |
| Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Craniofacial Abnormalities, Jaw Abnormalities, Jaw Diseases, Maxillofacial Abnormalities, Mouth Abnormalities, Musculoskeletal Abnormalities, Stomatognathic Diseases, Stomatognathic System Abnormalities, cleft palate, mouth disorder, musculoskeletal system disorder | Recruiting | Not applicable | 2026-08-07 | NCT07752849 |