subvalvular aortic stenosis
subvalvular aortic stenosis
Explore linked clinical trials. Standard reference: MONDO:0006987124 results · Page 1 of 5
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices | Ventricular Outflow Obstruction, Ventricular Outflow Obstruction, Left, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not applicable | 2026-10-09 | NCT07806149 | |
| Human Experimental Models of Pain (HEMP) | Acute Pain, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not applicable | 2026-10-09 | NCT07549490 | |
| Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository | Cardiomyopathy, Hypertrophic Obstructive, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Death, Death, Sudden, Death, Sudden, Cardiac, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, cardiac arrest, cardiomyopathy, cardiovascular disorder, familial hypertrophic cardiomyopathy, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-10-09 | NCT05100420 | |
| Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathy | Angina Pectoris, Arterial Occlusive Diseases, Chest Pain, Neurologic Manifestations, Pain, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, arteriosclerosis disorder, cardiomyopathy, cardiovascular disorder, coronary artery disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, myocardial ischemia, subvalvular aortic stenosis, vascular disorder | Not yet recruiting | Not applicable | 2026-10-08 | NCT07865364 | |
| A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Danon disease, Hypertrophy, Hypertrophy, Left Ventricular, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, X-linked disease, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, disorder of glycogen metabolism, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, inborn carbohydrate metabolic disorder, inborn errors of metabolism, intellectual disability, lysosomal storage disease, metabolic disease, nervous system disorder, subvalvular aortic stenosis | Recruiting | Phase 2 | 2026-10-06 | NCT06092034 | |
| BHB-1893 Versus Metoprolol for Symptomatic Obstructive Hypertrophic Cardiomyopathy | Cardiomyopathy, Hypertrophic Obstructive, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Phase 3 | 2026-10-02 | NCT07755904 | |
| A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-30 | NCT07107373 | |
| COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM) | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-30 | NCT06372457 | |
| Aficamten and Patient-Reported Outcomes in Real-World nHCM | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not stated | 2026-09-29 | NCT07846176 | |
| Evaluation of Mavacamten-Based Practice in Chinese Adults With Obstructive Hypertrophic Cardiomyopathy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not stated | 2026-09-29 | NCT07846059 | |
| Individualized Exercise Training in Hypertrophic Cardiomyopathy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not applicable | 2026-09-23 | NCT07835854 | |
| A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Phase 4 | 2026-09-16 | NCT06112743 | |
| The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Enrolling by invitation | Phase 4 | 2026-09-15 | NCT07103655 | |
| A Real-World Study on Hypertrophic Cardiomyopathy in Chinese Population | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-09-15 | NCT06775665 | |
| Gradual Tapering or Discontinuation of Beta-Blockers After Stabilization With Mavacamten Therapy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Not applicable | 2026-09-11 | NCT07815301 | |
| Mechanisms of Atrial Pathoelectrophysiology in HCM | Arrhythmias, Cardiac, Pathologic Processes, Pathological Conditions, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, atrial fibrillation, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-09-11 | NCT07454135 | |
| Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Not yet recruiting | Phase 4 | 2026-09-08 | NCT07807384 | |
| Study of LX2006 Gene Therapy in Friedreich Ataxia Cardiomyopathy | Cardiomegaly, Cardiomyopathies, Secondary, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Friedreich ataxia, Hypertrophy, Hypertrophy, Left Ventricular, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Spinocerebellar Degenerations, aortic valve disorder, aortic valve stenosis, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, cerebellar disorder, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, spinal cord disorder, subvalvular aortic stenosis | Recruiting | Phase 2 | 2026-09-02 | NCT07721025 | |
| Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, restrictive cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-02 | NCT05112237 | |
| A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy | Cardiomyopathy, Hypertrophic Obstructive, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Phase 3 | 2026-08-26 | NCT06481891 | |
| Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition | Arrhythmogenic Right Ventricular Dysplasia, Familial, 1, Tako-tsubo cardiomyopathy, Ventricular Dysfunction, Ventricular Dysfunction, Left, aortic valve disorder, aortic valve stenosis, cardiac sarcoidosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertensive heart disease, hypertrophic cardiomyopathy, myocarditis, subvalvular aortic stenosis | Recruiting | Not stated | 2026-08-26 | NCT06409585 | |
| A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Phase 3 | 2026-08-24 | NCT07021976 | |
| A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart failure, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-08-19 | NCT05489705 | |
| Stratification, Management, and Guidance of Hypertrophic Cardiomyopathy Patients Using Hybrid Digital Twin Solutions | aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-08-17 | NCT07131371 | |
| Study of the Progression of Chronic Cardiovascular Conditions | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ventricular Outflow Obstruction, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, familial dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, hypertensive disorder, hypertrophic cardiomyopathy, laminopathy, subvalvular aortic stenosis, vascular disorder | Recruiting | Not stated | 2026-08-12 | NCT07420907 |