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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
Pediatric Evaluation and Registry for Liver Cholestasis in CanadaAbnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1RecruitingNot stated2026-10-08NCT07411716
Long-Term SafEty and Clinical Outcomes of LivmArli in Patients in the United States (LEAP-US)Abnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1RecruitingNot stated2026-10-08NCT06193928
A Study of the Effectiveness, Safety and the Long-term Outcomes of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC) Who Take Odevixibat (Bylvay) in Chinaprogressive familial intrahepatic cholestasis type 1RecruitingNot stated2026-10-01NCT07588880
Odevixibat Outcomes in Patients With PFIC Versus an External Control Cohort (OvEC-PFIC)progressive familial intrahepatic cholestasis type 1Active, not recruitingNot stated2026-10-01NCT07497724
A Study of the Effectiveness, Safety and the Long-term Outcomes of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC) Who Take Odevixibat (Bylvay) in South Koreaprogressive familial intrahepatic cholestasis type 1RecruitingNot stated2026-10-01NCT07185919
Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome or Progressive Familial Intrahepatic Cholestasis in the European Union (LEAP-EU)Abnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Pathological Conditions, Signs and Symptoms, Pruritus, Signs and Symptoms, Skin Manifestations, Skin and Connective Tissue Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1, skin disorderRecruitingPhase 42026-06-23NCT07290257
Dental Dyschromia and Quality of Life in Early Prolonged HyperbilirubinemiaAbnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dental Diseases, Digestive System Abnormalities, Digestive System Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Stomatognathic Diseases, Tooth Discoloration, bile duct disorder, biliary atresia, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, hyperbilirubinemia, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1, tooth disorderRecruitingNot stated2026-05-12NCT06506734
DEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASEprogressive familial intrahepatic cholestasis type 1RecruitingNot applicable2026-03-27NCT07317193
A Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)Abnormalities, Multiple, Alagille syndrome, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, bile duct disorder, biliary tract disorder, cardiovascular disorder, cholestasis, congenital heart disease, hereditary disease, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1RecruitingNot stated2026-02-20NCT07293897
Prospective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)progressive familial intrahepatic cholestasis type 1RecruitingNot stated2025-01-24NCT06778174
Genotype-phenotype Relationship Between Cryptogenic Cholestasis and Familial Intrahepatic CholestasisDigestive System Diseases, bile duct disorder, biliary tract disorder, cholestasis, intrahepatic cholestasis, liver disorder, progressive familial intrahepatic cholestasis type 1RecruitingNot stated2025-01-17NCT06781242
NAtural Course and Prognosis of PFIC and Effect of Biliary Diversionprogressive familial intrahepatic cholestasis type 1Enrolling by invitationNot stated2025-01-17NCT03930810
Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancersprogressive familial intrahepatic cholestasis type 1RecruitingNot stated2025-01-16NCT06777914