hereditary hemorrhagic telangiectasia
hereditary hemorrhagic telangiectasia
Explore linked clinical trials. Standard reference: MONDO:001918031 results ยท Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Phase 1b Study of TX002100 in Participants With Hematologic Support-Dependent Hereditary Hemorrhagic Telangiectasia (HHT) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Not yet recruiting | Phase 1 | 2026-10-07 | NCT07863609 | |
| Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriovenous hemangioma/malformation, cardiovascular disorder, disease, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Phase 1 / Phase 2 | 2026-10-05 | NCT07601425 | |
| Pregnancy in Women With Rare Multisystemic Vascular Diseases: COGRare5 Study | Abnormalities, Multiple, Bone Diseases, Developmental, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Marfan syndrome, Skin and Connective Tissue Diseases, arteriovenous hemangioma/malformation, bone disorder, cardiovascular disorder, central nervous system disorder, congenital heart disease, connective tissue disorder, heart disorder, hematologic disorder, hemorrhagic disease, hereditary disease, hereditary hemorrhagic telangiectasia, lymphatic system disorder, lymphedema, musculoskeletal system disorder, nervous system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not stated | 2026-09-28 | NCT04194619 | |
| Bevacizumab in the Treatment of HHT | hereditary hemorrhagic telangiectasia | Recruiting | Phase 2 | 2026-09-18 | NCT07828015 | |
| Body Donation in HHT | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not applicable | 2026-09-17 | NCT07826845 | |
| A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Phase 3 | 2026-09-17 | NCT07743671 | |
| A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epistaxis, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, nasal disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Phase 1 / Phase 2 | 2026-09-16 | NCT06659640 | |
| DIAG723 in Adults With Hereditary Hemorrhagic Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, lung disorder, pulmonary arterial hypertension, pulmonary hypertension, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Phase 1 / Phase 2 | 2026-09-08 | NCT07623525 | |
| Topical TOR-582 Treatment of Epistaxis in HHT | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epistaxis, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, nasal disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Not yet recruiting | Phase 1 | 2026-08-21 | NCT07667413 | |
| Institutional Registry of Haemorrhagic Hereditary Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not stated | 2026-07-30 | NCT01761981 | |
| Comprehensive HHT Outcomes Registry of the United States (CHORUS) | Arteriovenous Malformations, Cerebral, Cardiovascular Abnormalities, Central Nervous System Vascular Malformations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Epistaxis, Gastrointestinal Hemorrhage, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, arteriovenous hemangioma/malformation, arteriovenous malformations of the brain, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system malformation, cerebrovascular disorder, digestive system disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, intracranial arterial disease, nasal disorder, nervous system disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not stated | 2026-07-17 | NCT06259292 | |
| Prospective Study of Antiplatelet and Anticoagulation Therapy in Hereditary Haemorrhagic Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epistaxis, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, nasal disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not applicable | 2026-07-10 | NCT05641142 | |
| Bevacizumab In Hereditary Hemorrhagic Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Phase 2 | 2026-05-05 | NCT04404881 | |
| CHORUS - Comprehensive HHT Outcomes Registry of the United States (Formerly OUR HHT Registry) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, arteriovenous hemangioma/malformation, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Not stated | 2026-04-22 | NCT04150822 | |
| Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz) | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epistaxis, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, anemia, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, nasal disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Phase 2 / Phase 3 | 2026-03-19 | NCT03850964 | |
| Assess Safety and Efficacy of VAD044 in HHT Patients | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, arteriovenous hemangioma/malformation, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Phase 1 / Phase 2 | 2026-03-17 | NCT05406362 | |
| Quality of Life in Pediatric Participants With HHT | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Not yet recruiting | Not stated | 2026-03-16 | NCT07474428 | |
| Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) Patients | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epistaxis, Hemic and Lymphatic Diseases, Hemorrhage, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Signs and Symptoms, Respiratory, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, nasal disorder, otorhinolaryngologic disease, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Phase 2 | 2026-03-11 | NCT04976036 | |
| Efficacy and Tolerance of Treatment With Bevacizumab for Severe Liver Involvement With High Cardiac Output in Hereditary Hemorrhagic Telangiectasia Within the French Hereditary Hemorrhagic Telangiectasia Network | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, hypertensive disorder, lung disorder, pulmonary hypertension, respiratory system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Enrolling by invitation | Not stated | 2026-03-03 | NCT07445347 | |
| Non-Invasive Detection of Pulmonary Right-to-Left Shunts Using the SONAS Ultrasound Device | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Pulmonary Arteriovenous Fistulas, atrial septal defect, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, congenital heart disease, heart disorder, heart septal defect, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, ischemic stroke, nervous system disorder, patent foramen ovale, stroke disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not applicable | 2026-02-17 | NCT07414446 | |
| Institutional Registry of Rare Diseases | Abnormalities, Multiple, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cardiovascular Abnormalities, Ciliopathies, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cushing syndrome, Digestive System Abnormalities, Digestive System Diseases, Disease Attributes, Eosinophilia, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Gaucher disease, Hemic and Lymphatic Diseases, Hereditary Complement Deficiency Diseases, Hirschsprung disease, Hypersensitivity, Delayed, Hypersensitivity, Immediate, Immunoglobulin G4-Related Disease, Imprinting Disorders, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Lysosomal Storage Diseases, Nervous System, Male Urogenital Diseases, Mast Cell Activation Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Neoplasms, Germ Cell and Embryonal, Neoplasms, Multiple Primary, Neoplasms, Nerve Tissue, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Overweight, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Prader-Willi syndrome, Primary Immunodeficiency Diseases, Rare Diseases, Skin Abnormalities, Skin and Connective Tissue Diseases, Urogenital Abnormalities, Urogenital Diseases, Wilson disease, adrenal gland disorder, adrenal gland hyperfunction, adrenogenital syndrome, amyloidosis, angioedema, angiomatosis, aortic valve disorder, aortic valve stenosis, autoimmune disease, basal ganglia disorder, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, chromosomal disorder, colonic disorder, congenital adrenal hyperplasia, connective tissue neoplasm, demyelinating disease, digestive system disorder, disorder of sexual differentiation, ectodermal dysplasia syndrome, endocrine system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, gonadal disorder, heart disorder, heart valve disorder, hematologic disorder, hemorrhagic disease, hereditary angioedema, hereditary disease, hereditary hemorrhagic telangiectasia, hereditary neoplastic syndrome, hereditary skin disorder, hypertensive disorder, hypertrophic cardiomyopathy, immune system disorder, inborn error of immunity, inborn errors of metabolism, inborn metal metabolism disorder, inflammatory bowel disease, inherited neurodegenerative disorder, intellectual disability, intestinal disorder, leukocyte disorder, liver disorder, lung disorder, lymphatic system disorder, lymphoproliferative syndrome, lysosomal lipid storage disorder, lysosomal storage disease, malignant endocrine neoplasm, mastocytosis, megacolon, metabolic disease, movement disorder, multiple endocrine neoplasia, neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, neuroendocrine neoplasm, nutritional disorder, obesity disorder, overnutrition, paraganglioma, pheochromocytoma, primitive neuroectodermal tumor, proteostasis deficiencies, pulmonary hypertension, respiratory system disorder, sarcoidosis, skin disorder, skin vascular disease, sphingolipidosis, steroid inherited metabolic disorder, subvalvular aortic stenosis, telangiectasis, urticaria, vascular disorder, vascular hemostatic disease, vascular malformation, von Hippel-Lindau disease | Recruiting | Not stated | 2026-01-14 | NCT06573723 | |
| Immunological Effects of Iron Supplementation in HHT Disease | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, immune system disorder, inborn error of immunity, leukocyte disorder, leukopenia, lymphopenia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Recruiting | Not applicable | 2025-10-03 | NCT07111598 | |
| Cardiac Evaluation in Hereditary Hemorrhagic Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Not yet recruiting | Not stated | 2025-08-14 | NCT07101575 | |
| Quality of Life in Patients With Hemorrhagic Telangiectasia | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, cardiovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Enrolling by invitation | Not stated | 2025-03-30 | NCT06261333 | |
| Hereditary Hemorrhagic Telangiectasia and Neurovascular Manifestations, in the Danish HHT Database | Cardiovascular Abnormalities, Central Nervous System Vascular Malformations, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, arteriovenous hemangioma/malformation, arteriovenous malformations of the brain, brain disorder, cardiovascular disorder, central nervous system disorder, central nervous system malformation, cerebrovascular disorder, hematologic disorder, hemorrhagic disease, hereditary hemorrhagic telangiectasia, intracranial arterial disease, nervous system disorder, telangiectasis, vascular disorder, vascular hemostatic disease, vascular malformation | Active, not recruiting | Not stated | 2025-03-30 | NCT05933330 |