laminopathy
laminopathy
Explore linked clinical trials. Standard reference: MONDO:002110670 results · Page 1 of 3
Clinical trials
Swipe the table sideways for more columns.
| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dilatation, Pathologic, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-10-01 | NCT07137338 | |
| A Study Observing Disease Progression in a Patient With Hutchinson-Gilford Progeria Syndrome (HGPS) | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Nutritional and Metabolic Diseases, hereditary disease, inborn errors of metabolism, laminopathy, metabolic disease, progeroid syndrome | Not yet recruiting | Not stated | 2026-09-24 | NCT07839351 | |
| Observatoire Des Patients Atteints de Laminopathies et Emerinopathies (Observatory for PAtients With Laminopathies and Emerinopathies) | Autosomal Emery-Dreifuss Muscular Dystrophy, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Emery-Dreifuss Muscular Dystrophy 1, Emery-Dreifuss muscular dystrophy, Muscular Disorders, Atrophic, X-linked Emery-Dreifuss muscular dystrophy, X-linked disease, hereditary disease, laminopathy, muscle tissue disorder, muscular dystrophy, musculoskeletal system disorder, nervous system disorder, neuromuscular disease | Recruiting | Not stated | 2026-09-21 | NCT03058185 | |
| Observational Study of Natural History of BAG3 Gene Mutation-Associated Dilated Cardiomyopathy in Chinese Adults | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Not stated | 2026-09-16 | NCT07646600 | |
| Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Nutritional and Metabolic Diseases, Skin Diseases, Metabolic, Skin and Connective Tissue Diseases, congenital generalized lipodystrophy, familial partial lipodystrophy, hereditary disease, inborn errors of metabolism, laminopathy, lipodystrophy, metabolic disease, skin disorder | Recruiting | Phase 3 | 2026-09-11 | NCT07220785 | |
| Creating Stem Cells From a Progeria Patient's Blood to Test Candidate Treatments in the Lab | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Nutritional and Metabolic Diseases, hereditary disease, inborn errors of metabolism, laminopathy, metabolic disease, progeroid syndrome | Not yet recruiting | Not stated | 2026-09-10 | NCT07803432 | |
| RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases | Arrhythmias, Cardiac, Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Not stated | 2026-09-10 | NCT07491237 | |
| A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-09-04 | NCT07241104 | |
| Sexual Quality of Life in Female Patients With Lipodystrophy Syndromes or Turner's Syndrome: a Case-control Study | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Sex Chromosome Disorders, Skin Diseases, Metabolic, Skin and Connective Tissue Diseases, Turner syndrome, Urogenital Abnormalities, Urogenital Diseases, cardiovascular disorder, chromosomal disorder, congenital heart disease, disorder of sexual differentiation, endocrine system disorder, familial partial lipodystrophy, gonadal disorder, gonadal dysgenesis, heart disorder, hereditary disease, laminopathy, lipodystrophy, metabolic disease, sex chromosome disorder of sex development, skin disorder | Not yet recruiting | Not stated | 2026-09-02 | NCT07799012 | |
| Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, restrictive cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-02 | NCT05112237 | |
| An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-09-01 | NCT07426419 | |
| Study of the Progression of Chronic Cardiovascular Conditions | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ventricular Outflow Obstruction, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, familial dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, hypertensive disorder, hypertrophic cardiomyopathy, laminopathy, subvalvular aortic stenosis, vascular disorder | Recruiting | Not stated | 2026-08-12 | NCT07420907 | |
| Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, idiopathic cardiomyopathy, laminopathy | Recruiting | Not applicable | 2026-08-11 | NCT06920030 | |
| Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS) | Adnexal Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cysts, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Nutritional and Metabolic Diseases, Skin Diseases, Metabolic, Skin and Connective Tissue Diseases, Urogenital Diseases, endocrine system disorder, familial partial lipodystrophy, female reproductive system disorder, gonadal disorder, hereditary disease, laminopathy, lipodystrophy, metabolic disease, neoplasm, ovarian cyst, ovarian disorder, polycystic ovary syndrome, skin disorder | Recruiting | Not applicable | 2026-08-10 | NCT07412028 | |
| A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-08-07 | NCT07606274 | |
| MyocarditIRM-Génétique - Genetic Sub-study of the French Cohort of Acute Myocarditis Cases Diagnosed by MRI | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, acute myocarditis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Active, not recruiting | Not stated | 2026-07-21 | NCT07717073 | |
| Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Nutritional and Metabolic Diseases, Skin Diseases, Metabolic, Skin and Connective Tissue Diseases, familial partial lipodystrophy, hereditary disease, laminopathy, lipodystrophy, metabolic disease, skin disorder | Recruiting | Phase 3 | 2026-07-16 | NCT06679270 | |
| Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-07-14 | NCT06902896 | |
| the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 2 | 2026-07-09 | NCT07692256 | |
| Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-07-02 | NCT07516288 | |
| A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-06-26 | NCT06464588 | |
| Pediatric Cardiomyopathy Mutation Analysis | Cardiomegaly, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypertrophy, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, arrhythmogenic right ventricular cardiomyopathy, cardiomyopathy, cardiovascular disorder, congenital heart disease, dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, left ventricular noncompaction, restrictive cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-06-22 | NCT02432092 | |
| A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Active, not recruiting | Not stated | 2026-06-12 | NCT05981092 | |
| AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor | Arrhythmias, Cardiac, Atrial Remodeling, Cardiomegaly, Cardiotoxicity, Chemically-Induced Disorders, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Consciousness Disorders, Drug-Related Side Effects and Adverse Reactions, Infarction, Necrosis, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Syncope, Unconsciousness, Ventricular Dysfunction, Ventricular Dysfunction, Left, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, injury, ischemic disease, laminopathy, myocardial infarction, myocardial ischemia, nervous system disorder, radiation injury, vascular disorder | Recruiting | Not stated | 2026-06-01 | NCT06699056 | |
| Mainstreaming Genetic Testing for Non-Ischemic Cardiomyopathy in Western Canada | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Enrolling by invitation | Not applicable | 2026-05-08 | NCT07345338 |