primary dysautonomia
primary dysautonomia
Explore linked clinical trials. Standard reference: MONDO:0021809252 results ยท Page 1 of 11
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Guanfacine and Cromolyn Sodium for POTS: The DBPOTS Trial | Cognition Disorders, Cognitive Dysfunction, Fatigue, Mental Fatigue, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, cognitive disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia, psychiatric disorder | Not yet recruiting | Early phase 1 | 2026-10-09 | NCT07757555 | |
| Open-Label Access to ATH434 for Patients Who Completed Study ATH434-201 in France | autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathy | Enrolling by invitation | Phase 2 | 2026-10-09 | NCT07729852 | |
| Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition | autonomic nervous system disorder, nervous system disorder, primary dysautonomia | Recruiting | Phase 4 | 2026-10-09 | NCT07468604 | |
| An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy | autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathy | Recruiting | Phase 2 | 2026-10-09 | NCT07197866 | |
| A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy | autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathy | Active, not recruiting | Phase 2 | 2026-10-09 | NCT06568237 | |
| Cardioneuroablation for Reflex Syncope and Exercise Capacity | Consciousness Disorders, Neurobehavioral Manifestations, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Syncope, Syncope, Vasovagal, Unconsciousness, autonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia | Active, not recruiting | Not applicable | 2026-10-09 | NCT06440291 | |
| NightWare and Cardiovascular Health in Veterans With PTSD | Inflammation, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Stress Disorders, Traumatic, acute stress disorder, autonomic nervous system disorder, cardiovascular disorder, nervous system disorder, post-traumatic stress disorder, primary dysautonomia, psychiatric disorder | Recruiting | Not applicable | 2026-10-08 | NCT06419959 | |
| Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual Trial | Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, synucleinopathy, tauopathy | Recruiting | Phase 1 / Phase 2 | 2026-10-07 | NCT07863180 | |
| Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations | Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Mast Cell Activation Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Connective and Soft Tissue, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, alpha-gal syndrome, autonomic nervous system disorder, bone marrow disorder, chronic myelomonocytic leukemia, connective tissue neoplasm, cutaneous mastocytosis, hematologic disorder, immune system disorder, leukemia, mastocytosis, myelodysplastic/myeloproliferative disease, myeloid leukemia, neoplasm, nervous system disorder, orthostatic intolerance, primary dysautonomia, skin disorder, skin neoplasm | Recruiting | Not stated | 2026-10-07 | NCT07143669 | |
| Inappropriate Sinus Tachycardia Registry | autonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia | Recruiting | Not stated | 2026-10-07 | NCT05107635 | |
| A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy | autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, primary dysautonomia, synucleinopathy | Active, not recruiting | Phase 2 | 2026-10-06 | NCT05923866 | |
| NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease | Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypotension, Orthostatic, Menkes disease, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, X-linked disease, autonomic nervous system disorder, brain disorder, cardiovascular disorder, central nervous system disorder, disorder of pilosebaceous unit, hereditary disease, hypotensive disorder, inborn errors of metabolism, inborn metal metabolism disorder, inherited neurodegenerative disorder, intellectual disability, metabolic disease, nervous system disorder, orthostatic intolerance, primary dysautonomia, skin disorder, vascular disorder | Recruiting | Phase 1 / Phase 2 | 2026-10-05 | NCT07398508 | |
| The Precision Mito- Mito Map COMPASS Study | Bacterial Infections and Mycoses, Borrelia infectious disease, Chronic Disease, Disease Attributes, Fatigue, Infections, Lyme disease, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, Signs and Symptoms, autonomic nervous system disorder, bacterial infectious disease, fibromyalgia, gram-negative bacterial infections, inborn mitochondrial metabolism disorder, metabolic disease, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease, orthostatic intolerance, post-treatment Lyme disease syndrome, primary dysautonomia, rheumatic disorder, spirochaetales infections, tick-borne infectious disease, vector-borne disease | Not yet recruiting | Not stated | 2026-10-02 | NCT07856121 | |
| Autonomic and Renal Contributions to Hypertension With ADT | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Male Urogenital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, autonomic nervous system disorder, cardiovascular disorder, hypertensive disorder, kidney disorder, male reproductive organ cancer, male reproductive system disorder, neoplasm, nervous system disorder, primary dysautonomia, prostate cancer, prostate disorder, urinary system disorder, vascular disorder | Recruiting | Phase 4 | 2026-09-30 | NCT07848828 | |
| Ceasing Alpha-blockers Early After Resection of the Prostate (The CLEAR Trial) | Genital Diseases, Hypotension, Orthostatic, Male Urogenital Diseases, Urogenital Diseases, autonomic nervous system disorder, benign prostatic hyperplasia, cardiovascular disorder, hypotensive disorder, male reproductive system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia, prostate disorder, vascular disorder | Not yet recruiting | Phase 4 | 2026-09-29 | NCT07846579 | |
| Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities? | autonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia | Recruiting | Not stated | 2026-09-29 | NCT06616363 | |
| Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome | Abnormalities, Multiple, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Down syndrome, Neurobehavioral Manifestations, Neurologic Manifestations, autonomic nervous system disorder, chromosomal disorder, hereditary disease, intellectual disability, nervous system disorder, primary dysautonomia | Recruiting | Phase 3 | 2026-09-28 | NCT07238465 | |
| Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, autonomic nervous system disorder, hepatic porphyria, hereditary coproporphyria, hereditary disease, hereditary skin disorder, liver disorder, metabolic disease, nervous system disorder, orthostatic intolerance, porphyria, porphyria due to ALA dehydratase deficiency, primary dysautonomia, skin disorder | Active, not recruiting | Not stated | 2026-09-28 | NCT05344599 | |
| Long COVID Immune Profiling | COVID-19, Chronic Disease, Coronaviridae Infections, Disease Attributes, Infections, Neurologic Manifestations, Nidovirales infectious disease, Orthocoronavirinae infectious disease, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Post-Infectious Disorders, RNA Virus Infections, Signs and Symptoms, autonomic nervous system disorder, long COVID-19, lung disorder, nervous system disorder, orthostatic intolerance, pneumonia, primary dysautonomia, respiratory system disorder, respiratory tract infectious disorder, viral infectious disease, viral pneumonia | Active, not recruiting | Not stated | 2026-09-25 | NCT06027255 | |
| RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome | autonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia | Not yet recruiting | Not applicable | 2026-09-24 | NCT07837804 | |
| fMRI in Postural Tachycardia Syndrome | autonomic nervous system disorder, nervous system disorder, orthostatic intolerance, primary dysautonomia | Active, not recruiting | Not applicable | 2026-09-24 | NCT04137757 | |
| Time-Domain Heart Rate Variability and QT Interval in Children With Epilepsy | Arrhythmias, Cardiac, Pathologic Processes, Pathological Conditions, Signs and Symptoms, autonomic nervous system disorder, brain disorder, cardiovascular disorder, central nervous system disorder, epilepsy, heart disorder, nervous system disorder, primary dysautonomia | Not yet recruiting | Not stated | 2026-09-22 | NCT07834983 | |
| First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD) | Cognition Disorders, Cognitive Dysfunction, Dyskinesias, Muscle Hypertonia, Muscle Rigidity, Neurologic Manifestations, Neuromuscular Manifestations, Parasomnias, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Tremor, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, mood disorder, movement disorder, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neurodegenerative disease, parkinsonian disorder, primary dysautonomia, psychiatric disorder, sleep-wake disorder, synucleinopathy | Recruiting | Phase 1 | 2026-09-21 | NCT07216066 | |
| VisMemoPD Protocol: an Observational Pilot Study on Spatial and Topographical Memory in Patients With Parkinson's Disease and Parkinsonism | Cognition Disorders, Cognitive Dysfunction, Mild Cognitive Impairment, Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, psychiatric disorder, synucleinopathy, tauopathy | Not yet recruiting | Not stated | 2026-09-18 | NCT07827963 | |
| Neurodegenerative Diseases Registry | Neurologic Manifestations, Ocular Motility Disorders, Parkinson disease, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, autonomic nervous system disorder, basal ganglia disorder, brain disorder, central nervous system disorder, cranial nerve neuropathy, eye disorder, movement disorder, multiple system atrophy, nervous system disorder, neurodegenerative disease, ophthalmoplegia, palsy, parkinsonian disorder, primary dysautonomia, progressive supranuclear palsy, synucleinopathy, tauopathy | Recruiting | Not stated | 2026-09-18 | NCT04472130 |