ClinicalTrials HQ

Mayo Clinic Florida

Mayo Clinic Florida

Jacksonville, Florida, United States

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Clinical trials

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TrialConditionsStatusPhaseUpdatedMore infoNCT ID
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia GravisNeoplasms by Site, Paraneoplastic Syndromes, Nervous System, autoimmune disease, autoimmune disorder of the nervous system, immune system disorder, myasthenia gravis, neoplasm, nervous system disorder, neurodegenerative disease, neuromuscular disease, neuromuscular junction disease, paraneoplastic syndromeRecruitingPhase 1 / Phase 22026-10-09NCT06359041
Phase 1 Study of CLR 125 in Triple Negative Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast cancer, breast disorder, breast neoplasm, neoplasm, skin disorder, triple-negative breast carcinomaRecruitingPhase 12026-10-08NCT07311993
An Open-label Study of XEN1101 in EpilepsyNeurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Tonic-Clonic Seizures, brain disorder, central nervous system disorder, epilepsy, focal epilepsy, nervous system disorder, visual epilepsyEnrolling by invitationPhase 32026-10-08NCT05718817
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, nervous system disorder, visual epilepsyRecruitingPhase 32026-10-08NCT05716100
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizuresbrain disorder, central nervous system disorder, epilepsy, nervous system disorderRecruitingPhase 32026-10-08NCT05667142
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Skin and Connective Tissue Diseases, melanocytic neoplasm, melanoma, neoplasm, neuroendocrine neoplasm, primitive neuroectodermal tumor, skin disorder, skin neoplasmRecruitingPhase 32026-10-07NCT06246916
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)Frontotemporal Lobar Degeneration, Neurologic Manifestations, Nutritional and Metabolic Diseases, Ocular Motility Disorders, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, TDP-43 proteinopathy, amyotrophic lateral sclerosis, basal ganglia disorder, brain disorder, central nervous system disorder, cognitive disorder, corticobasal degeneration disorder, cranial nerve neuropathy, dementia, eye disorder, frontotemporal dementia, frontotemporal dementia with motor neuron disease, metabolic disease, motor neuron disorder, movement disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, ophthalmoplegia, palsy, proteostasis deficiencies, psychiatric disorder, spinal cord disorder, tauopathyRecruitingNot stated2026-10-07NCT04363684
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Diseaseidiopathic pulmonary fibrosis, interstitial lung disease, lung disorder, pulmonary fibrosis, respiratory system disorderEnrolling by invitationPhase 32026-10-06NCT04905693
SARC041: Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated LiposarcomaAdvanced Dedifferentiated LiposarcomaActive, not recruitingPhase 32026-10-05NCT04967521
A Phase 1 Study of the Safety and Tolerability of CTX-10726Digestive System Diseases, Digestive System Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Liver Neoplasms, Male Urogenital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, adenocarcinoma, benign urinary system neoplasm, carcinoma, endometrium neoplasm, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, hepatocellular carcinoma, kidney cancer, kidney disorder, liver disorder, neoplasm, renal cell carcinoma, urinary system disorder, uterine disorderRecruitingPhase 12026-10-02NCT07419841
Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss OutcomeBody Weight, Nutritional and Metabolic Diseases, Overweight, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, nutritional disorder, obesity disorder, overnutritionEnrolling by invitationNot stated2026-10-02NCT05408728
(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic MastocytosisMast Cell Activation Disorders, Mastocytosis, Systemic, Neoplasms by Histologic Type, Neoplasms, Connective and Soft Tissue, connective tissue neoplasm, immune system disorder, indolent systemic mastocytosis, mastocytosis, neoplasmActive, not recruitingPhase 22026-10-02NCT03731260
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic AmenorrheaFemale Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Menstruation Disturbances, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, amenorrhea, female infertility, female reproductive system disorder, functional hypothalamic amenorrhea, infertility disorderRecruitingPhase 22026-10-01NCT07235917
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast CancerNeoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorderRecruitingPhase 22026-10-01NCT06369285
OCS DCD Heart + CAP Continued Follow-UpHeart TransplantActive, not recruitingNot stated2026-09-29NCT05741723
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast CancerHER2 positive breast carcinoma, Neoplasms by Site, Skin and Connective Tissue Diseases, breast disorder, breast neoplasm, neoplasm, skin disorderActive, not recruitingPhase 32026-09-29NCT05132582
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsDigestive System Diseases, Digestive System Neoplasms, Disease Attributes, Esophageal Neoplasms, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Head and Neck Neoplasms, Male Urogenital Diseases, Neoplasm Metastasis, Neoplasms by Histologic Type, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, benign urinary system neoplasm, carcinoma, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, esophageal adenocarcinoma, esophageal disorder, esophageal squamous cell carcinoma, gastric adenocarcinoma, lung disorder, lung neoplasm, malignant endocrine neoplasm, malignant mesothelioma, malignant pancreatic neoplasm, mesothelial neoplasm, mesothelioma, neoplasm, pancreas disorder, pancreatic neoplasm, peritoneal mesothelioma, pleural mesothelioma, pleural neoplasm, respiratory system disorder, respiratory tract neoplasm, squamous cell carcinoma, squamous cell neoplasm, transitional cell carcinoma, urinary bladder cancer, urinary bladder disorder, urinary bladder neoplasm, urinary system disorderRecruitingPhase 12026-09-28NCT07277413
Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)CNS demyelinating autoimmune disease, Infections, Neoplasms by Site, Neuroinflammatory Diseases, Paraneoplastic Syndromes, Nervous System, acute transverse myelitis, autoimmune disease, autoimmune disorder of the nervous system, central nervous system disorder, central nervous system infectious disorder, cranial nerve neuropathy, demyelinating disease, eye disorder, immune system disorder, myelitis, neoplasm, nervous system disorder, neurodegenerative disease, optic nerve disorder, optic neuritis, paraneoplastic syndrome, spinal cord disorderRecruitingPhase 32026-09-24NCT07100990
Estimation of Biomechanical Aortic Wall Properties in Healthy and Aneurysmal Aortas Using Novel Imaging TechniquesAneurysm, abdominal aortic aneurysm, aortic aneurysm, aortic disorder, cardiovascular disorder, vascular disorderRecruitingNot applicable2026-09-24NCT02548546
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast CancerCarcinoma, Ductal, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Ductal, Lobular, and Medullary, Skin and Connective Tissue Diseases, adenocarcinoma, breast disorder, breast ductal adenocarcinoma, breast neoplasm, carcinoma, epithelial neoplasm, neoplasm, skin disorderRecruitingNot applicable2026-09-23NCT07214532
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple MyelomaMultiple Myeloma Refractory; Multiple Myeloma in RelapseRecruitingPhase 22026-09-21NCT07096778
Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)Chronic Disease, Craniocerebral Trauma, Disease Attributes, Hematoma, Hematoma, Subdural, Hematoma, Subdural, Chronic, Hemorrhage, Intracranial Hemorrhage, Traumatic, Intracranial Hemorrhages, Pathologic Processes, Pathological Conditions, Signs and Symptoms, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, injury, nervous system disorder, nervous system injury, vascular disorderRecruitingNot stated2026-09-21NCT06181994
International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)Aneurysm, brain aneurysm, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, intracranial arterial disease, nervous system disorder, vascular disorderRecruitingNot stated2026-09-21NCT06174727
A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)Digestive System Diseases, Digestive System Neoplasms, Neoplasm Metastasis, Neoplasms by Site, Neoplastic Processes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, endocrine system disorder, malignant endocrine neoplasm, neoplasm, pancreas disorder, pancreatic neoplasmRecruitingPhase 22026-09-18NCT07450859
Feasibility and Usability of a Chest-Strap Ambulatory ECG Monitor in Active Individuals in Comparison With a Traditional Ambulatory ECG Patch Monitor (MoMe ARC)Arrhythmias, Cardiac, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, heart disorderRecruitingNot stated2026-09-17NCT07772817