Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Active, not recruiting · NCT02962414 · Registry updated 2026-08-21Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Malformations of Cortical Development, Group I, Neoplasms, Multiple Primary, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, central nervous system malformation, cerebral cortical dysplasia, hamartoma, hereditary disease, hereditary neoplastic syndrome, inherited neurodegenerative disorder, neoplasm, nervous system disorder, neurocutaneous syndrome, neurodegenerative disease, tuberous sclerosis, visual epilepsy | Active, not recruiting | Phase 3 | 2026-08-21 | NCT02962414 |
1 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Novartis Pharmaceuticals | 432 |
14 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Atlantic Health Morristown MC | Morristown | United States | 1 |
| Childrens Hospital Of Philadelphia | Philadelphia | United States | 18 |
| Cinn Children Hosp Medical Center | Cincinnati | United States | 10 |
| Connecticut Childrens Medical Cntr | Hartford | United States | 1 |
| David Geffen School of Medicine at UCLA | Los Angeles | United States | 1 |
| Minnesota Epilepsy Group | Saint Paul | United States | 1 |
| Oregon Health Sciences University | Portland | United States | 33 |
| Rady Children s Hospital | San Diego | United States | 2 |
| Texas Childrens Hospital | Houston | United States | 12 |
| Texas Scottish Rite Hos for Child | Dallas | United States | 1 |
| TGen APNNA | Phoenix | United States | 1 |
| UCSF Benioff Children s Hospital | Oakland | United States | 2 |
| University of Chicago Medical Center | Chicago | United States | 152 |
| University of Colorado School of Medicine | Aurora | United States | 12 |