Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations
Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations
Active, not recruiting · NCT04641442 · Registry updated 2026-10-09Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations | Digestive System Diseases, X-linked lymphoproliferative disease due to XIAP deficiency, digestive system disorder, enterocolitis, gastroenteritis, intestinal disorder | Active, not recruiting | Phase 2 | 2026-10-09 | NCT04641442 |
1 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Novartis Pharmaceuticals | 432 |
8 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Bambino Gesu Hospital | Roma | Italy | 1 |
| Centrum detske revmatologie a autoinflamatornich onemocneni | Prague | Czechia | 1 |
| Children´s Hospital of Philadelphia | Philadelphia | United States | 1 |
| Cincinnati Children's Hospital | Cincinnati | United States | 66 |
| Great Ormond Street Hospital | London | United Kingdom | 38 |
| Seattle Children´s Hospital | Seattle | United States | 1 |
| Texas Children´s Hospital | Houston | United States | 1 |
| Ustav Imunologie 2 LF UK a FN Motol | Prague | Czechia | 1 |