HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome
HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome
Active, not recruiting · NCT05127226 · Registry updated 2026-08-20Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome | Abnormalities, Multiple, Angelman syndrome, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Imprinting Disorders, central nervous system disorder, chromosomal disorder, hereditary disease, movement disorder, nervous system disorder | Active, not recruiting | Phase 1 / Phase 2 | 2026-08-20 | NCT05127226 |
1 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Ionis Pharmaceuticals, Inc. | 22 |
11 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Azienda Ospedaliera Universitaria Pisana | Pisa | Italy | 13 |
| Boston Children's Hospital | Boston | United States | 20 |
| Colorado Children's Hospital Research Institute | Aurora | United States | 2 |
| Necker-Enfants Malades Hospital | Paris | France | 3 |
| Rady Children's Hospital | San Diego | United States | 52 |
| Rush University Medical Center | Chicago | United States | 283 |
| Sheba Medical Center | Ramat Gan | Israel | 25 |
| STRONG Group University of Oxford | Oxford | United Kingdom | 1 |
| Sydney Children's Hospital, Kids Cancer Centre | Randwick | Australia | 1 |
| Texas Children's Hospital | Houston | United States | 187 |
| University of North Carolina at Chapel Hill School of Medicine | Carrboro | United States | 3 |