Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
Recruiting · NCT05482893 · Registry updated 2026-09-28Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) | Biliary Tract Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Neoplasms by Site, biliary tract disorder, colonic disorder, colorectal cancer, colorectal neoplasm, digestive system disorder, digestive system neoplasm, intestinal disorder, neoplasm, pancreatic ductal adenocarcinoma, rectal disorder | Recruiting | Phase 1 / Phase 2 | 2026-09-28 | NCT05482893 |
2 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Merck Sharp & Dohme LLC | 650 |
| Phanes Therapeutics | 3 |
11 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| City of Hope (City of Hope National Medical Center, City of Hope Medical Center) | Duarte | United States | 15 |
| Dana-Farber Cancer Institute (DFCI) | Boston | United States | 4 |
| Duke Cancer Center | Durham | United States | 44 |
| MD Anderson Cancer Center, GI Medical Oncology Dept | Houston | United States | 1 |
| NEXT Oncology | Fairfax | United States | 31 |
| Norton Cancer Institute | Louisville | United States | 26 |
| Sarah Cannon Research Institute (SCRI) | Denver | United States | 3 |
| University of Iowa | Iowa City | United States | 284 |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh | United States | 4 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Madison | United States | 249 |
| Usc Norris Comprehensive Cancer Center | Los Angeles | United States | 67 |