A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
Active, not recruiting · NCT05736731 · Registry updated 2025-04-25Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression | Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Thoracic Neoplasms, bronchial neoplasm, bronchogenic carcinoma, cancer, colonic disorder, colorectal adenocarcinoma, colorectal cancer, colorectal carcinoma, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, intestinal disorder, lung disorder, lung neoplasm, malignant endocrine neoplasm, malignant pancreatic neoplasm, neoplasm, non-small cell lung carcinoma, non-small cell squamous lung carcinoma, pancreas disorder, pancreatic neoplasm, rectal disorder, respiratory system disorder, respiratory tract neoplasm | Active, not recruiting | Phase 1 / Phase 2 | 2025-04-25 | NCT05736731 |
2 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| A2 Biotherapeutics Inc. | 5 |
| Tempus AI | 18 |
8 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Banner Health | Gilbert | United States | 6 |
| Mayo Clinic Rochester | Rochester | United States | 133 |
| MD Anderson Cancer Center | Houston | United States | 589 |
| Moffitt Cancer Center | Tampa | United States | 2 |
| NYU Langone Medical Center | New York | United States | 32 |
| UCLA Medical Center | Los Angeles | United States | 4 |
| University of California San Diego | La Jolla | United States | 54 |
| Washington University | St Louis | United States | 182 |