First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228
First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228
Active, not recruiting · NCT05737628 · Registry updated 2026-01-16Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| First-in-human Dose Escalation and Expansion Study With the SIRPα-directed Monoclonal Antibody BYON4228 | Hemic and Lymphatic Diseases, Neoplasms by Histologic Type, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoma, lymphoproliferative syndrome, neoplasm | Active, not recruiting | Phase 1 | 2026-01-16 | NCT05737628 |
1 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Byondis B.V. | 3 |
12 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| ASST Spedali Civili Di Brescia | Brescia | Italy | 11 |
| Centro Integral Oncológico Clara Campal (CIOCC) Hospital Universitario HM Sanchinarro | Madrid | Spain | 1 |
| Hospital Universitari Vall d'Hebron | Barcelona | Spain | 45 |
| Institut Català d'Oncologia | Barcelona | Spain | 2 |
| Instituto Europeo di Oncologia | Milan | Italy | 5 |
| IRCCS Ospedale San Raffaele | Milan | Italy | 47 |
| Istituto di Candiolo - Fondazione del Piemonte per l'Oncologia - IRCCS | Candiolo | Italy | 2 |
| Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRCCS IRST | Ravenna | Italy | 1 |
| Radboud UMC | Nijmegen | Netherlands | 25 |
| The Christie NHS Foundation Trust | Manchester | United Kingdom | 40 |
| University Hospitals Plymouth NHS Trust | Plymouth | United Kingdom | 10 |
| Vrije Universiteit Medisch Centrum | Amsterdam | Netherlands | 2 |