A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Recruiting · NCT06051695 · Registry updated 2026-06-12Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression | Adnexal Diseases, Digestive System Diseases, Digestive System Neoplasms, Disease Attributes, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Histologic Type, Neoplasms by Site, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Recurrence, Thoracic Neoplasms, Urogenital Diseases, Urogenital Neoplasms, adenoma, bronchial neoplasm, bronchogenic carcinoma, cancer, colonic disorder, colonic neoplasm, colorectal adenocarcinoma, colorectal cancer, colorectal carcinoma, colorectal neoplasm, digestive system disorder, digestive system neoplasm, endocrine system disorder, epithelial neoplasm, female reproductive system disorder, female reproductive system neoplasm, gonadal disorder, intestinal disorder, lung cancer, lung disorder, lung neoplasm, malignant colon neoplasm, malignant endocrine neoplasm, malignant mesothelioma, malignant pancreatic neoplasm, mesothelial neoplasm, mesothelioma, neoplasm, non-small cell lung carcinoma, non-small cell squamous lung carcinoma, ovarian cancer, ovarian disorder, pancreas disorder, pancreatic neoplasm, pleural neoplasm, rectal cancer, rectal disorder, rectal neoplasm, respiratory system disorder, respiratory tract neoplasm | Recruiting | Phase 1 / Phase 2 | 2026-06-12 | NCT06051695 |
2 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| A2 Biotherapeutics Inc. | 5 |
| Tempus AI | 18 |
12 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Banner Health | Gilbert | United States | 6 |
| Fred Hutchinson Cancer Center | Seattle | United States | 250 |
| Mayo Clinic | Jacksonville | United States | 122 |
| Mayo Clinic Rochester | Rochester | United States | 133 |
| Moffitt Cancer Center | Tampa | United States | 2 |
| NYU Langone Medical Center | New York | United States | 32 |
| Stanford University | Stanford | United States | 213 |
| The Ohio State University Comprehensive Cancer Center | Columbus | United States | 29 |
| UCLA Medical Center | Los Angeles | United States | 4 |
| UCSD Moores Cancer Center | La Jolla | United States | 20 |
| Vanderbilt University Medical Center | Nashville | United States | 427 |
| Washington University | St Louis | United States | 182 |