Cardiomegaly
Cardiomegaly
Explore linked clinical trials. Standard reference: MESH:M000995291 results · Page 1 of 4
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Danon disease, Hypertrophy, Hypertrophy, Left Ventricular, Neurobehavioral Manifestations, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, X-linked disease, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, disorder of glycogen metabolism, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, inborn carbohydrate metabolic disorder, inborn errors of metabolism, intellectual disability, lysosomal storage disease, metabolic disease, nervous system disorder, subvalvular aortic stenosis | Recruiting | Phase 2 | 2026-10-06 | NCT06092034 | |
| A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dilatation, Pathologic, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-10-01 | NCT07137338 | |
| Sodium Lowering Vascular Effects Trial | Cardiomegaly, Hypertrophy, Hypertrophy, Left Ventricular, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Ventricular Dysfunction, Ventricular Dysfunction, Left, cardiovascular disorder, heart disorder | Active, not recruiting | Not applicable | 2026-10-01 | NCT05388032 | |
| Can Exercise Electrocardiography Discriminate Hypertensive Heart Disease From Obstructive Coronary Artery Disease? A Multimodality Imaging Study | Cardiomegaly, Hypertrophy, Hypertrophy, Left Ventricular, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, heart disorder | Recruiting | Not stated | 2026-09-29 | NCT07847463 | |
| Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia | Cardiac Hypertrophy, Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dyskinesias, Friedreich ataxia, Hypertrophy, Neurologic Manifestations, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spinocerebellar Degenerations, atactic disorder, non-human animal, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, cerebellar disorder, heart disorder, hereditary disease, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, spinal cord disorder | Recruiting | Phase 1 | 2026-09-28 | NCT05302271 | |
| Observational Study of Natural History of BAG3 Gene Mutation-Associated Dilated Cardiomyopathy in Chinese Adults | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Not stated | 2026-09-16 | NCT07646600 | |
| Evaluation of the Efficacy of Diagnostic Support Algorithms in Chest X-rays- LuAna Trial | Cardiomegaly, Hypertrophy, Lung Injury, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Pleural Effusion, Thoracic Injuries, cardiovascular disorder, heart disorder, injury, lung disorder, pleural disorder, pneumothorax, pulmonary edema, respiratory system disorder | Recruiting | Not applicable | 2026-09-16 | NCT06686251 | |
| RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases | Arrhythmias, Cardiac, Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pathologic Processes, Pathological Conditions, Signs and Symptoms, atrial fibrillation, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Not stated | 2026-09-10 | NCT07491237 | |
| Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS | Cardiomegaly, Hypertrophy, Hypertrophy, Left Ventricular, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Ventricular Outflow Obstruction, aortic valve disorder, aortic valve stenosis, cardiovascular disorder, heart disorder, heart valve disorder | Active, not recruiting | Not applicable | 2026-09-10 | NCT03094143 | |
| A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-09-04 | NCT07241104 | |
| Study of LX2006 Gene Therapy in Friedreich Ataxia Cardiomyopathy | Cardiomegaly, Cardiomyopathies, Secondary, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Friedreich ataxia, Hypertrophy, Hypertrophy, Left Ventricular, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Spinocerebellar Degenerations, aortic valve disorder, aortic valve stenosis, brain disorder, cardiomyopathy, cardiovascular disorder, central nervous system disorder, cerebellar disorder, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, inborn mitochondrial metabolism disorder, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, spinal cord disorder, subvalvular aortic stenosis | Recruiting | Phase 2 | 2026-09-02 | NCT07721025 | |
| Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, restrictive cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-02 | NCT05112237 | |
| An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-09-01 | NCT07426419 | |
| Study of the Progression of Chronic Cardiovascular Conditions | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Ventricular Outflow Obstruction, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, familial dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, hypertensive disorder, hypertrophic cardiomyopathy, laminopathy, subvalvular aortic stenosis, vascular disorder | Recruiting | Not stated | 2026-08-12 | NCT07420907 | |
| Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular Lead | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, idiopathic cardiomyopathy, laminopathy | Recruiting | Not applicable | 2026-08-11 | NCT06920030 | |
| A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-08-07 | NCT07606274 | |
| Angiotensin Receptor Blocker After TAVR in Severe Aortic Stenosis With Left Ventricular Hypertrophy (ARBITAR) | Cardiomegaly, Hypertrophy, Hypertrophy, Left Ventricular, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Ventricular Outflow Obstruction, aortic valve disorder, aortic valve stenosis, cardiovascular disorder, heart disorder, heart valve disorder | Not yet recruiting | Phase 4 | 2026-07-29 | NCT07735130 | |
| Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy | Amyloid Neuropathies, Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypertrophy, Hypertrophy, Left Ventricular, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, amyloidosis, cardiovascular disorder, familial amyloid neuropathy, heart disorder, hereditary amyloidosis, hereditary disease, inborn errors of metabolism, inherited neurodegenerative disorder, metabolic disease, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, proteostasis deficiencies | Not yet recruiting | Not applicable | 2026-07-29 | NCT07734285 | |
| MyocarditIRM-Génétique - Genetic Sub-study of the French Cohort of Acute Myocarditis Cases Diagnosed by MRI | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, acute myocarditis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Active, not recruiting | Not stated | 2026-07-21 | NCT07717073 | |
| Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 / Phase 2 | 2026-07-14 | NCT06902896 | |
| the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 2 | 2026-07-09 | NCT07692256 | |
| Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart failure, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-07-02 | NCT07516288 | |
| A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM) | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, hereditary disease, laminopathy | Recruiting | Phase 1 | 2026-06-26 | NCT06464588 | |
| Pediatric Cardiomyopathy Mutation Analysis | Cardiomegaly, Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypertrophy, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, aortic valve disorder, aortic valve stenosis, arrhythmogenic right ventricular cardiomyopathy, cardiomyopathy, cardiovascular disorder, congenital heart disease, dilated cardiomyopathy, heart disorder, heart failure, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, left ventricular noncompaction, restrictive cardiomyopathy, subvalvular aortic stenosis | Recruiting | Not stated | 2026-06-22 | NCT02432092 | |
| AI-based Echocardiography for Detection of Cardiac Amyloidosis | Amyloid Neuropathies, Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hypertrophy, Hypertrophy, Left Ventricular, Nutritional and Metabolic Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Sprains and Strains, amyloidosis, cardiovascular disorder, familial amyloid neuropathy, heart disorder, hereditary amyloidosis, hereditary disease, inborn errors of metabolism, inherited neurodegenerative disorder, injury, metabolic disease, nervous system disorder, neurodegenerative disease, neuromuscular disease, peripheral nervous system disorder, proteostasis deficiencies | Not yet recruiting | Not applicable | 2026-06-12 | NCT07529860 |