The Children's Hospital of Philadelphia
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States62 results · Page 1 of 3
Clinical trials
Swipe the table sideways for more columns.
| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study | Bone Diseases, Developmental, Chronic Pain, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Kyphosis, Musculoskeletal Abnormalities, Neurologic Manifestations, Pain, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Postoperative Complications, Postoperative Pain, Signs and Symptoms, Spinal Curvatures, bone disorder, musculoskeletal system disorder, pectus excavatum, scoliosis, vertebral column disorder | Active, not recruiting | Not stated | 2026-10-08 | NCT02998138 | |
| Validation of Nanosensor Oxygen Measurement | Nutritional and Metabolic Diseases, inborn mitochondrial metabolism disorder, inborn mitochondrial myopathy, metabolic disease, muscle tissue disorder, musculoskeletal system disorder, nervous system disorder, neuromuscular disease | Recruiting | Phase 1 | 2026-10-07 | NCT06819683 | |
| Setrusumab vs Placebo for Osteogenesis Imperfecta | Bone Diseases, Developmental, Collagen Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Skin and Connective Tissue Diseases, bone disorder, connective tissue disorder, hereditary disease, musculoskeletal system disorder, osteochondrodysplasia, osteogenesis imperfecta | Active, not recruiting | Phase 2 / Phase 3 | 2026-10-06 | NCT05125809 | |
| A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Muscular Atrophy, Spinal, Type II, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spinal Muscular Atrophies of Childhood, central nervous system disorder, hereditary disease, inherited neurodegenerative disorder, motor neuron disorder, nervous system disorder, neurodegenerative disease, neuromuscular disease, proximal spinal muscular atrophy, spinal cord disorder, spinal muscular atrophy, spinal muscular atrophy, type III | Recruiting | Phase 2 | 2026-10-02 | NCT07047144 | |
| The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, Skin Abnormalities, Skin and Connective Tissue Diseases, arterial calcification of infancy, autosomal recessive hypophosphatemic rickets, autosomal recessive inherited pseudoxanthoma elasticum, cardiovascular disorder, connective tissue disorder, hematologic disorder, hemorrhagic disease, hereditary disease, hereditary skin disorder, hypophosphatemic rickets, autosomal recessive, 1, skin disorder, vascular disorder, vascular hemostatic disease | Active, not recruiting | Phase 1 | 2026-09-29 | NCT05734196 | |
| Effect of Patiromer in Children Under 12 Years of Age With High Blood Potassium Levels | Hyperkalemia, Nutritional and Metabolic Diseases, Water-Electrolyte Imbalance, metabolic disease | Recruiting | Phase 2 | 2026-09-25 | NCT05766839 | |
| Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals | Early-Onset Scoliosis Deformity of Spine | Active, not recruiting | Not applicable | 2026-09-24 | NCT04058561 | |
| Long-Term Follow-Up Study After Gene-Modified Cell Treatment in Kite Studies | Hemic and Lymphatic Diseases, Neoplasms by Site, autoimmune disease, hematologic disorder, hematopoietic and lymphoid system neoplasm, immune system disorder, neoplasm | Enrolling by invitation | Not stated | 2026-09-21 | NCT05041309 | |
| Molecular Basis of Food Allergy | Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, food allergy, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorder | Enrolling by invitation | Not stated | 2026-09-21 | NCT01832324 | |
| A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome | Epilepsies, Myoclonic, Epilepsy, Generalized, Epileptic Syndromes, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, nervous system disorder, visual epilepsy | Recruiting | Phase 3 | 2026-09-15 | NCT04462770 | |
| A Study to Compare the Long-term Outcomes After Two Different Anaesthetics | Chemically-Induced Disorders, nervous system disorder, poisoning, toxic encephalopathy | Active, not recruiting | Phase 3 | 2026-09-10 | NCT03089905 | |
| Study to Evaluate the Efficacy and Safety of BBP-418 (Ribitol) in Patients With Limb Girdle Muscular Dystrophy 2I (LGMD2I) | autosomal recessive limb-girdle muscular dystrophy type 2I | Active, not recruiting | Phase 3 | 2026-09-09 | NCT05775848 | |
| Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS Patients | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Hemic and Lymphatic Diseases, autoimmune disease, autoimmune lymphoproliferative syndrome, autoimmune lymphoproliferative syndrome type 1, hereditary disease, hypersplenism, immune system disorder, immunoproliferative disorder, lymphatic system disorder, lymphoproliferative syndrome, splenic disorder | Recruiting | Phase 2 | 2026-09-08 | NCT06730126 | |
| Observational Approach Versus Surgical Intervention for Stones | Calculi, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Kidney Calculi, Male Urogenital Diseases, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Urinary Calculi, Urogenital Diseases, kidney disorder, nephrolithiasis, urinary system disorder, urolithiasis | Recruiting | Not applicable | 2026-09-03 | NCT07718802 | |
| Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab | Atrophy, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Muscular Atrophy, Spinal, Type II, Neurologic Manifestations, Neuromuscular Manifestations, Pathological Conditions, Anatomical, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Spinal Muscular Atrophies of Childhood, central nervous system disorder, hereditary disease, inherited neurodegenerative disorder, motor neuron disorder, muscular atrophy, nervous system disorder, neurodegenerative disease, neuromuscular disease, proximal spinal muscular atrophy, spinal cord disorder, spinal muscular atrophy, spinal muscular atrophy, type III | Active, not recruiting | Phase 3 | 2026-09-01 | NCT05626855 | |
| HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI) | Congenital Hyperinsulinism, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, Nutritional and Metabolic Diseases, glucose metabolism disease, hyperinsulinism, hypoglycemia, metabolic disease, pancreas disorder | Active, not recruiting | Phase 2 | 2026-08-26 | NCT04732416 | |
| SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes | Nutritional and Metabolic Diseases, autoimmune disease, diabetes mellitus, endocrine system disorder, glucose metabolism disease, immune system disorder, metabolic disease, type 1 diabetes mellitus | Recruiting | Phase 2 | 2026-08-24 | NCT07187531 | |
| Parental Decision-Making for Children With Relapsed Neuroblastoma | Death, Neoplasms by Histologic Type, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, Neuroectodermal Tumors, Primitive, Peripheral, Pathologic Processes, Pathological Conditions, Signs and Symptoms, epithelial neoplasm, neoplasm, neuroblastoma, neuroepithelial neoplasm, primitive neuroectodermal tumor | Active, not recruiting | Not stated | 2026-08-20 | NCT02282735 | |
| A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG | Dyskinesias, Neurologic Manifestations, PMM2-congenital disorder of glycosylation, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, atactic disorder, non-human animal, nervous system disorder | Active, not recruiting | Phase 2 / Phase 3 | 2026-08-14 | NCT06892288 | |
| A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care | Digestive System Diseases, Eosinophilia, Hemic and Lymphatic Diseases, Hypersensitivity, Immediate, digestive system disorder, eosinophilic esophagitis, esophageal disorder, esophagitis, gastroenteritis, hematologic disorder, immune system disorder, leukocyte disorder | Active, not recruiting | Not stated | 2026-08-12 | NCT06693531 | |
| TReatment for ImmUne Mediated PathopHysiology | Brain Diseases, Metabolic, Digestive System Diseases, Hepatic Insufficiency, Nutritional and Metabolic Diseases, acute liver failure, brain disorder, central nervous system disorder, hepatic encephalopathy, liver disorder, liver failure, metabolic disease, nervous system disorder | Active, not recruiting | Phase 2 | 2026-08-12 | NCT04862221 | |
| A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy | Epileptic Encephalopathy | Recruiting | Phase 1 / Phase 2 | 2026-08-11 | NCT07227857 | |
| A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections | Abnormalities, Multiple, Barth syndrome, Bone Marrow Failure Disorders, Cardiovascular Abnormalities, Cohen syndrome, Congenital Abnormalities, Congenital Bone Marrow Failure Syndromes, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Cytopenia, Digestive System Diseases, Hemic and Lymphatic Diseases, Kostmann syndrome, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Nutritional and Metabolic Diseases, Shwachman-Diamond syndrome, X-linked disease, agranulocytosis, autoimmune disease, bone marrow disorder, cardiovascular disorder, congenital heart disease, exocrine pancreatic insufficiency, heart disorder, hematologic disorder, hereditary disease, immune system disorder, inborn errors of metabolism, leukocyte disorder, leukopenia, lipomatosis, metabolic disease, neutropenia, pancreas disorder | Recruiting | Phase 3 | 2026-08-06 | NCT06056297 | |
| The REPLACE Registry for Cholbam® (Cholic Acid) | Abnormalities, Multiple, Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Male Urogenital Diseases, Nutritional and Metabolic Diseases, Peroxisomal Disorders, Urogenital Diseases, Zellweger spectrum disorders, brain disorder, central nervous system disorder, hereditary disease, inborn disorder of bile acid synthesis, inborn errors of metabolism, kidney disorder, liver disorder, metabolic disease, nervous system disorder, urinary system disorder | Active, not recruiting | Not stated | 2026-07-31 | NCT03115086 | |
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hypercalciuria, Hypercalciuric Hypocalcemia, Familial, Hypocalcemia, Male Urogenital Diseases, Musculoskeletal Abnormalities, Nutritional and Metabolic Diseases, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Urogenital Diseases, Urological Manifestations, Water-Electrolyte Imbalance, calcinosis, calcium metabolic disease, endocrine system disorder, hypoparathyroidism, kidney disorder, metabolic disease, muscle tissue disorder, musculoskeletal system disorder, nephrocalcinosis, nephrolithiasis, nervous system disorder, neuromuscular disease, parathyroid gland disorder, urinary system disorder, urolithiasis | Active, not recruiting | Phase 3 | 2026-07-29 | NCT05680818 |