Manchester University NHS Foundation Trust
Manchester University NHS Foundation Trust
Manchester, United Kingdom22 results · Page 1 of 1
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia | Dyslipidemias, Hypercholesterolemia, Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, hyperlipidemia, metabolic disease | Active, not recruiting | Not stated | 2026-09-30 | NCT04579367 | |
| Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide | Chronic Disease, Digestive System Diseases, Disease Attributes, Hepatitis D, Chronic, Hepatitis, Chronic, Infections, Pathologic Processes, Pathological Conditions, Signs and Symptoms, RNA Virus Infections, hepatitis, hepatitis D virus infection, liver disorder, viral hepatitis, viral infectious disease | Recruiting | Phase 2 / Phase 3 | 2026-09-10 | NCT07454837 | |
| A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants | Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Cerebral Small Vessel Diseases, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Fabry disease, Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Lysosomal Storage Diseases, Nervous System, Nutritional and Metabolic Diseases, X-linked disease, brain disorder, cardiovascular disorder, central nervous system disorder, cerebrovascular disorder, hereditary disease, inborn errors of metabolism, lysosomal lipid storage disorder, lysosomal storage disease, metabolic disease, nervous system disorder, sphingolipidosis, vascular disorder | Recruiting | Phase 3 | 2026-09-01 | NCT06904261 | |
| Study of WAL0921 in Patients With Glomerular Kidney Diseases | Diabetes Complications, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, IgA glomerulonephritis, Male Urogenital Diseases, Urogenital Diseases, autoimmune disease, diabetes mellitus, diabetic kidney disease, endocrine system disorder, glomerulonephritis, immune system disorder, kidney disorder, minimal change disease, nephritis, nephrosis, primary focal segmental glomerulosclerosis, urinary system disorder | Recruiting | Phase 2 | 2026-08-03 | NCT06466135 | |
| Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study | Arterial Occlusive Diseases, Chronic Disease, Chronic Limb-Threatening Ischemia, Disease Attributes, Pathologic Processes, Pathological Conditions, Signs and Symptoms, arteriosclerosis disorder, atherosclerosis, cardiovascular disorder, ischemic disease, peripheral arterial disease, peripheral vascular disease, vascular disorder | Active, not recruiting | Not stated | 2026-07-30 | NCT06149650 | |
| Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk | cardiovascular disorder, heart disorder, heart failure | Recruiting | Not applicable | 2026-07-28 | NCT07067658 | |
| Adalimumab Dose Adjustment for Pediatric Uveitis Treatment Trial | anterior uveitis, eye disorder, intermediate uveitis, panuveitis, uveal disorder, uveitis | Not yet recruiting | Phase 4 | 2026-07-13 | NCT07699107 | |
| Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH) | Bone Diseases, Developmental, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Dwarfism, Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Skin and Connective Tissue Diseases, achondroplasia, bone disorder, connective tissue disorder, cutaneous mucinosis, endocrine system disorder, hereditary disease, hereditary endocrine growth disease, inborn carbohydrate metabolic disorder, inborn errors of metabolism, lysosomal storage disease, metabolic disease, mucopolysaccharidosis, mucopolysaccharidosis type 4, musculoskeletal system disorder, osteochondrodysplasia | Recruiting | Phase 2 | 2026-07-13 | NCT07169279 | |
| A Novel, Regulated Gene Therapy (NGN-401) Study for Females With Rett Syndrome | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Rett syndrome, Signs and Symptoms, X-linked disease, hereditary disease, inherited neurodegenerative disorder, intellectual disability, nervous system disorder, neurodevelopmental disorder, psychiatric disorder | Active, not recruiting | Phase 3 | 2026-06-10 | NCT05898620 | |
| Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Sex Chromosome Disorders, X-linked disease, chromosomal disorder, fragile X syndrome, hereditary disease, inherited neurodegenerative disorder, intellectual disability, nervous system disorder | Active, not recruiting | Phase 2 / Phase 3 | 2026-05-27 | NCT03802799 | |
| Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial | Arterial Occlusive Diseases, Ventricular Outflow Obstruction, Ventricular Outflow Obstruction, Left, aortic valve disorder, aortic valve stenosis, arteriosclerosis disorder, cardiomyopathy, cardiovascular disorder, coronary artery disorder, heart disorder, heart valve disorder, hypertrophic cardiomyopathy, myocardial ischemia, subvalvular aortic stenosis, vascular disorder | Recruiting | Not applicable | 2026-05-22 | NCT07120776 | |
| Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases | Alport syndrome, Collagen Diseases, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Hemorrhage, IgA glomerulonephritis, Male Urogenital Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, Skin Manifestations, Skin and Connective Tissue Diseases, Urogenital Abnormalities, Urogenital Diseases, autoimmune disease, blood coagulation disease, cardiovascular disorder, connective tissue disorder, focal segmental glomerulosclerosis, glomerulonephritis, hematologic disorder, hemorrhagic disease, hereditary nephritis, immune system disorder, immunoglobulin A vasculitis, kidney disorder, macular corneal dystrophy, minimal change disease, nephritis, nephrosis, purpura, skin disorder, skin vascular disease, type III hypersensitivity disease, urinary system disorder, vascular disorder, vascular hemostatic disease, vasculitis | Recruiting | Phase 2 | 2026-05-12 | NCT05003986 | |
| Mothers Working to Prevent Early Stillbirth Study 20-28 | Death, Female Urogenital Diseases and Pregnancy Complications, Fetal Death, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Perinatal Death, Urogenital Diseases, pregnancy disorder, pregnancy disorder with abortive outcome | Recruiting | Not stated | 2026-02-27 | NCT06005272 | |
| DENTOFACIAL-PBT Stage 2 - Feasibility Study | Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Head and Neck Neoplasms, Neoplasms by Site, childhood malignant neoplasm, developmental disability, head and neck cancer, injury, neoplasm, neurodevelopmental disorder, psychiatric disorder, radiation injury | Enrolling by invitation | Not stated | 2026-01-26 | NCT07057284 | |
| Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole | Cough, Pathological Conditions, Signs and Symptoms, Respiration Disorders, Signs and Symptoms, Signs and Symptoms, Respiratory, idiopathic pulmonary fibrosis, interstitial lung disease, lung disorder, pulmonary fibrosis, respiratory system disorder | Recruiting | Phase 3 | 2025-12-22 | NCT04965298 | |
| CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG) | Dyslipidemias, Lipid Metabolism Disorders, Nutritional and Metabolic Diseases, hyperlipidemia, hypertriglyceridemia, metabolic disease | Active, not recruiting | Phase 3 | 2025-12-01 | NCT05681351 | |
| Validation of Sensors for Long-term Non-Invasive Fetal Monitoring | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases and Pregnancy Complications, Fetal Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Urogenital Diseases, fetal growth restriction, hereditary endocrine growth disease, pregnancy disorder | Recruiting | Not applicable | 2025-05-01 | NCT06952777 | |
| Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial | Chronic Disease, Disease Attributes, Hemic and Lymphatic Diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Myeloproliferative Disorders, Neoplasms by Histologic Type, Pathologic Processes, Pathological Conditions, Signs and Symptoms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, acute biphenotypic leukemia, acute leukemia of ambiguous lineage, acute myeloid leukemia, bone marrow disorder, chronic myelomonocytic leukemia, hematologic disorder, immune system disorder, immunoproliferative disorder, leukemia, lymphatic system disorder, lymphoid leukemia, lymphoproliferative syndrome, myelodysplastic syndrome, myelodysplastic/myeloproliferative disease, myeloid leukemia, neoplasm | Recruiting | Phase 2 | 2025-04-17 | NCT06355583 | |
| Gene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type IIIA | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Mucopolysaccharidosis III, Nutritional and Metabolic Diseases, Skin and Connective Tissue Diseases, connective tissue disorder, cutaneous mucinosis, hereditary disease, inborn carbohydrate metabolic disorder, inborn errors of metabolism, lysosomal storage disease, metabolic disease, mucopolysaccharidosis, mucopolysaccharidosis type 3A | Active, not recruiting | Phase 1 / Phase 2 | 2025-03-30 | NCT04201405 | |
| Methylated Biomarkers Predictive of Endometrial Cancer Risk | Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Genital Diseases, Neoplasms by Site, Urogenital Diseases, Urogenital Neoplasms, endometrium neoplasm, female reproductive system disorder, female reproductive system neoplasm, neoplasm, uterine disorder | Active, not recruiting | Not stated | 2025-01-30 | NCT06800677 | |
| UNICORNS: Uveitis in Childhood Prospective National Cohort Study | eye disorder, uveal disorder, uveitis | Active, not recruiting | Not stated | 2024-10-04 | NCT05385757 | |
| Cardiometabolic Health in First Time Pregnancy | Nutritional and Metabolic Diseases, Pathologic Processes, Pathological Conditions, Signs and Symptoms, cardiovascular disorder, diabetes mellitus, disease, endocrine system disorder, glucose metabolism disease, heart disorder, metabolic disease, syndromic disease | Recruiting | Not stated | 2024-04-09 | NCT05856318 |