St. Louis Children's Hospital
St. Louis Children's Hospital
St Louis, Missouri, United States30 results · Page 1 of 2
Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Hemic and Lymphatic Diseases, Male Urogenital Diseases, Respiration Disorders, Urogenital Diseases, Vaso-Occlusive Crises, acute chest syndrome, acute kidney injury, anemia, familial hemolytic anemia, hematologic disorder, hemolytic anemia, hereditary disease, inherited hemoglobinopathy, kidney disorder, kidney failure, lung disorder, respiratory system disorder, sickle cell disease, urinary system disorder | Recruiting | Phase 2 | 2026-10-08 | NCT06699849 | |
| HCRN Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants | brain disorder, central nervous system disorder, hydrocephalus, nervous system disorder | Active, not recruiting | Not applicable | 2026-09-25 | NCT04177914 | |
| ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas | Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumor | Recruiting | Phase 2 | 2026-09-21 | NCT06838676 | |
| ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD | Brain Diseases, Metabolic, Brain Diseases, Metabolic, Inborn, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Lysosomal Storage Diseases, Nervous System, Nutritional and Metabolic Diseases, brain disorder, central nervous system disorder, disorder of glycogen metabolism, glycogen storage disease II, hereditary disease, inborn carbohydrate metabolic disorder, inborn errors of metabolism, lysosomal storage disease, metabolic disease, nervous system disorder | Active, not recruiting | Phase 3 | 2026-09-17 | NCT03911505 | |
| Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy | Cardiomegaly, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, aortic valve disorder, aortic valve stenosis, cardiomyopathy, cardiovascular disorder, dilated cardiomyopathy, heart disorder, heart valve disorder, hereditary disease, hypertrophic cardiomyopathy, laminopathy, restrictive cardiomyopathy, subvalvular aortic stenosis | Active, not recruiting | Not stated | 2026-09-02 | NCT05112237 | |
| PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma | Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Neuroectodermal Tumors, Primitive, brain disorder, brainstem cancer, central nervous system cancer, central nervous system disorder, diffuse intrinsic pontine glioma, epithelial neoplasm, glioma, malignant glioma, medulloblastoma, neoplasm, nervous system disorder, neuroepithelial neoplasm, primitive neuroectodermal tumor | Recruiting | Phase 2 | 2026-08-24 | NCT05096481 | |
| A-LiNK: Improving Outcomes in Autoimmune Liver Disease | Cholangitis, Sclerosing, Digestive System Diseases, Hepatic Insufficiency, Hepatitis, Chronic, autoimmune disease, autoimmune hepatitis, bile duct disorder, biliary tract disorder, cholangitis, chronic liver failure, hepatitis, immune system disorder, liver disorder, liver failure, primary sclerosing cholangitis | Recruiting | Not stated | 2026-08-19 | NCT05750498 | |
| TReatment for ImmUne Mediated PathopHysiology | Brain Diseases, Metabolic, Digestive System Diseases, Hepatic Insufficiency, Nutritional and Metabolic Diseases, acute liver failure, brain disorder, central nervous system disorder, hepatic encephalopathy, liver disorder, liver failure, metabolic disease, nervous system disorder | Active, not recruiting | Phase 2 | 2026-08-12 | NCT04862221 | |
| Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Epileptic Syndromes, Lennox-Gastaut syndrome, Neurologic Manifestations, Pathological Conditions, Signs and Symptoms, Signs and Symptoms, brain disorder, central nervous system disorder, epilepsy, hereditary disease, nervous system disorder, visual epilepsy | Recruiting | Not stated | 2026-08-06 | NCT05374824 | |
| COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Pulmonary Atresia, Ventricular Outflow Obstruction, aortic valve disorder, aortopulmonary window, cardiovascular disorder, congenital heart disease, heart disorder, heart septal defect, heart valve disorder, persistent truncus arteriosus, pulmonary valve insufficiency, pulmonary valve stenosis, tetralogy of fallot, transposition of the great arteries, vascular malformation | Recruiting | Not applicable | 2026-07-23 | NCT02744677 | |
| Safety Study of Viaskin® Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers) | Hypersensitivity, Immediate, Nut and Peanut Hypersensitivity, Peanut Hypersensitivity, allergic disease, food allergy, immune system disorder | Active, not recruiting | Phase 3 | 2026-07-22 | NCT07003919 | |
| A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Tourette syndrome, basal ganglia disorder, brain disorder, central nervous system disorder, hereditary disease, inherited neurodegenerative disorder, movement disorder, nervous system disorder, neurodegenerative disease, neurodevelopmental disorder, psychiatric disorder, tic disorder | Active, not recruiting | Phase 3 | 2026-07-22 | NCT06021522 | |
| ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND) | Respiration Disorders, adult acute respiratory distress syndrome, lung disorder, respiratory system disorder | Active, not recruiting | Not stated | 2026-07-14 | NCT05388708 | |
| Rethinking Early Airway Clearence Therapies | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorder | Not yet recruiting | Not applicable | 2026-07-10 | NCT07696338 | |
| Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorder | Recruiting | Not stated | 2026-07-08 | NCT04509050 | |
| Advanced SPinal Innovations With Robotics and Enabling Technology Registry | adolescent idiopathic scoliosis, bone disorder, idiopathic scoliosis, musculoskeletal system disorder, spondylolisthesis, spondylolysis, spondylosis, vertebral column disorder | Recruiting | Not stated | 2026-06-22 | NCT05071144 | |
| DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2) | Noonan syndrome 5, low grade glioma | Active, not recruiting | Phase 3 | 2026-05-14 | NCT05566795 | |
| HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN) | Pediatric Hydrocephalus | Recruiting | Not stated | 2026-05-14 | NCT00670735 | |
| AVATAR Anesthesia Alternative in Pediatric Radiotherapy: A Multi-Center Study | Anesthesia | Active, not recruiting | Not stated | 2026-04-13 | NCT03991156 | |
| Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children | Infections, Mononegavirales infectious disease, Paramyxoviridae infectious disease, Pneumovirus Infections, RNA Virus Infections, respiratory syncytial virus infectious disease, viral infectious disease | Recruiting | Phase 3 | 2026-02-09 | NCT05026749 | |
| COMPASSION S3 Post-Approval Study | Bites and Stings, Chemically-Induced Disorders, cardiovascular disorder, heart disorder, heart valve disorder, injury, poisoning, pulmonary valve insufficiency | Active, not recruiting | Not stated | 2026-02-03 | NCT04860765 | |
| Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial | Digestive System Diseases, Female Urogenital Diseases, Female Urogenital Diseases and Pregnancy Complications, Infections, Male Urogenital Diseases, Soft Tissue Infections, Urogenital Diseases, digestive system disorder, gastroenteritis, lung disorder, pneumonia, respiratory system disorder, respiratory tract infectious disorder, urinary system disorder, urinary tract infection | Recruiting | Not applicable | 2025-12-10 | NCT05471908 | |
| CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, Infant, Newborn, Diseases, cystic fibrosis, hereditary disease, lung disorder, pancreas disorder, respiratory system disorder | Active, not recruiting | Not stated | 2025-10-10 | NCT03350828 | |
| Quality of Pediatric Resuscitation in a Multicenter Collaborative | Cardiopulmonary Arrest, cardiac arrest, cardiovascular disorder, heart disorder | Recruiting | Not stated | 2025-10-02 | NCT02708134 | |
| ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent | Cardiovascular Abnormalities, Congenital Abnormalities, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, cardiovascular disorder, congenital heart disease, heart disorder, heart valve disorder, lung disorder, pulmonary valve insufficiency, respiratory system disorder, tetralogy of fallot | Active, not recruiting | Not applicable | 2025-09-25 | NCT03130777 |