ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Recruiting · NCT06430385 · Registry updated 2026-10-08Clinical trials
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| Trial | Conditions | Status | Phase | Updated | More info | NCT ID |
|---|---|---|---|---|---|---|
| ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS) | Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Neurobehavioral Manifestations, Neurologic Manifestations, Rett syndrome, X-linked disease, hereditary disease, inherited neurodegenerative disorder, intellectual disability, nervous system disorder | Recruiting | Phase 1 / Phase 2 | 2026-10-08 | NCT06430385 |
1 results · Page 1 of 1
Organizations
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| Organizations | Linked trials |
|---|---|
| Ionis Pharmaceuticals, Inc. | 22 |
12 results · Page 1 of 1
Research sites
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| Research sites | City | Country | Linked trials |
|---|---|---|---|
| Baylor College of Medicine | Houston | United States | 306 |
| Boston Children's Hospital | Boston | United States | 343 |
| British Columbia Children's Hospital | Vancouver | Canada | 1 |
| Children's Hospital of Philadelphia | Philadelphia | United States | 434 |
| CHU Dijon Bourgogne | Dijon | France | 12 |
| Gillette Children's Specialty Healthcare | Saint Paul | United States | 11 |
| Hospital Saint Joan de Deu | Barcelona | Spain | 1 |
| Kennedy Krieger | Baltimore | United States | 1 |
| Kepler University Hospital | Linz | Austria | 1 |
| Rady Children's Hospital | San Diego | United States | 52 |
| University of Colorado Hopsital - Anschutz Medical Campus | Aurora | United States | 1 |
| Vanderbilt University Medical Center | Nashville | United States | 427 |